Cytotoxic T-Lymphocyte Antigen-4 Gene Polymorphisms and Human T-Cell Lymphotrophic Virus-1 Infection: Their Associations with Hashimoto's Thyroiditis in Japanese Patients

CTLA-4 Gene Polymorphism at Position 49 in Exon 1 Reduces the Inhibitory Function of CTLA-4 and Contributes to the Pathogenesis of Graves’ Disease

2000 • 508 citations

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

1995 • 426 citations

CTLA4 Alanine-17 Confers Genetic Susceptibility to Graves’ Disease and to Type 1 Diabetes Mellitus¹

1997 • 408 citations

Lymphoproliferation in CTLA-4–Deficient Mice Is Mediated by Costimulation-Dependent Activation of CD4 + T Cells

1997 • 405 citations

HUMAN T CELL LEUKEMIA VIRUS TYPE I (HTLV-I) AND HUMAN DISEASES

1997 • 395 citations

CTLA4 Alanine-17 Confers Genetic Susceptibility to Graves' Disease and to Type 1 Diabetes Mellitus

1997 • 270 citations

Codon 17 Polymorphism of the Cytotoxic T Lymphocyte Antigen 4 Gene in Hashimoto’s Thyroiditis and Addison’s Disease1

1997 • 242 citations

The Causes of Autoimmune Thyroid Disease*

1989 • 209 citations

The Role of CTLA‐4 in the Regulation and Initiation of T‐Cell Responses

1996 • 208 citations

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population

1995 • 203 citations

CTLA4 promoter and exon 1 dimorphisms in multiple sclerosiso

1999 • 164 citations

The Development of Graves’ Disease and theCTLA-4Gene on Chromosome 2q33¹

1999 • 154 citations

Association of CTLA-4 Gene A-G Polymorphism (IDDM12 Locus) With Acute-Onset and Insulin-Depleted IDDM as Well as Autoimmune Thyroid Disease (Graves' Disease and Hashimoto's Thyroiditis) in the Japanese Population

1998 • 147 citations

CTLA4 Gene Polymorphism Confers Susceptibility to Graves' Disease in Japanese

1997 • 139 citations

Codon 17 Polymorphism of the Cytotoxic T Lymphocyte Antigen 4 Gene in Hashimoto's Thyroiditis and Addison's Disease

1997 • 130 citations

Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways?

1999 • 128 citations

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.

2000 • 113 citations

The Development of Graves' Disease and the CTLA-4 Gene on Chromosome 2q33

1999 • 102 citations

CTLA‐4, a Negative Regulator of T‐Lymphocyte Activation

1996 • 91 citations

No evidence for allelic association of a human CTLA‐4 promoter polymorphism with autoimmune thyroid disease in either population‐based case–control or family‐based studies

1998 • 68 citations

HTLV‐I infection in patients with autoimmune thyroiditis (Hashimoto's thyroiditis)

1992 • 65 citations

Linkage Analysis of Candidate Genes in Autoimmune Thyroid Disease: 1. Selected Immunoregulatory Genes

1998 • 64 citations

Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onset and autoimmune thyroid disease.

2000 • 62 citations

No Major Role for the CTLA-4 Gene in the Association of Autoimmune Thyroid Disease With IDDM

1998 • 58 citations

Association of HLA Antigen and Restriction Fragment Length Polymorphism of T Cell Receptor β- Chain Gene with Graves' Disease and Hashimoto's Thyroiditis*

1989 • 47 citations

Association of HTLV‐I with autoimmune thyroiditis in patients with adult T‐cell leukaemia (ATL) and in HTLV‐I carriers

1996 • 37 citations