Co-secretion of carboxypeptidase H and insulin from isolated rat islets of Langerhans

A Flexible System of Enzymatic Analysis

1972 • 4,133 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Fluorometric quantification of DNA in cells and tissue

1983 • 445 citations

A New in Vitro Model for the Study of Pancreatic A and B Cells*

1985 • 345 citations

Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins

1989 • 341 citations

Enkephalin convertase: purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules.

1982 • 283 citations

Purification and characterization of enkephalin convertase, an enkephalin-synthesizing carboxypeptidase.

1983 • 265 citations

Endocrine Pancreas: Three-Dimensional Reconstruction Shows Two Types of Islets of Langerhans

1979 • 236 citations

Requirement for calcium ion in insulin secretion by the perfused rat pancreas

1968 • 186 citations

The biosociology of pancreatic B cells

1987 • 164 citations

Identification of Proinsulin and C-Peptide in Human Serum by a Specific Immunoassay

1970 • 164 citations

Protein Transport by the Pancreas

1975 • 161 citations

The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing

1987 • 143 citations

The stimulus-secretion coupling of glucose-induced insulin release. Effect of exogenous pyruvate on islet function

1978 • 140 citations

Enzymes of glucose metabolism in normal mouse pancreatic islets

1970 • 114 citations

Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents

1989 • 113 citations

Secretion and Regulation of Two Biosynthetic Enzyme Activities, Peptidyl-Glycineα-Amidating Monooxygenase and a Carboxypeptidase, by Mouse Pituitary Corticotropic Tumor Cells*

1984 • 101 citations

Carboxypeptidase activity in the insulin secretory granule

1983 • 98 citations

Islet cell analysis and purification by light scatter and autofluorescence

1982 • 97 citations

Proteolytic conversion of proinsulin into insulin. Identification of a Ca2+-dependent acidic endopeptidase in isolated insulin-secretory granules

1987 • 69 citations

Secretory granules

1984 • 38 citations

(Met)enkephalin and carboxypeptidase processing enzyme are co-released from chromaffin cells by cholinergic stimulation

1985 • 23 citations

Radiometric assay for carboxypeptidase H (EC 3.4.17.10) and other carboxypeptidase B-like enzymes

1989 • 16 citations