Cellular and Subcellular Mechanisms of Cardiac Pacemaker Oscillations

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Electric current flow in excitable cells

1976 • 1,353 citations

LXXXVIII.On “relaxation-oscillations”

1926 • 958 citations

CALCIUM-DEPENDENT POTASSIUM ACTIVATION IN NERVOUS TISSUES

1978 • 760 citations

Prediction of repetitive firing behaviour from voltage clamp data on an isolated neurone soma

1971 • 752 citations

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

1975 • 684 citations

Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres.

1978 • 638 citations

LXXII.The heartbeat considered as a relaxation oscillation, and an electrical model of the heart

1928 • 515 citations

The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres

1968 • 488 citations

Calcium release from the sarcoplasmic reticulum.

1977 • 428 citations

Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres.

1976 • 407 citations

Digitalis arrhythmias: Role of oscillatory afterpotentials

1977 • 332 citations

ION MOVEMENTS DURING NERVE ACTIVITY

1959 • 325 citations

Changes in the intracellular concentration of free calcium ions in a pace‐maker neurone, measured with the metallochromic indicator dye arsenazo III.

1978 • 224 citations

Excitation-Contraction Coupling of Isolated Cardiac Fibers with Disrupted or Closed Sarcolemmas: CALCIUM-DEPENDENT CYCLIC AND TONIC CONTRACTIONS

1972 • 219 citations

Comparative physiology of the cardiac pacemaker mechanism.

1978 • 207 citations

Analysis of cardiac pacemaker potential using a "voltage clamp" technique

1966 • 197 citations

The initiation of the heartbeat

1975 • 186 citations

RECTIFICATION AND INDUCTANCE IN THE SQUID GIANT AXON

1941 • 161 citations

The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres

1969 • 141 citations

Effects of extracellular potassium on ventricular automaticity and evidence for a pacemaker current in mammalian ventricular myocardium.

1977 • 135 citations

A time- and voltage-dependent potassium current in the rabbit sinoatrial node cell

1976 • 127 citations

Effects of Internal Divalent Cations on Voltage-Clamped Squid Axons

1974 • 110 citations

Oscillations in calcium-cyclic AMP control loops form the basis of pacemaker activity and other high frequency biological rhythms

1977 • 104 citations

The effects of tension on acetylstrophanthidin-induced transient depolarizations and aftercontractions in canine myocardial and Purkinje tissues.

1976 • 100 citations

Slow repetitive activity from fast conductance changes in neurons.

1978 • 75 citations

Die Entstehung von ?Nachkontraktionen? im Herzmuskel unter Einwirkung von Calcium und von Digitalisglykosiden in Abh�ngigkeit von der Reizfrequenz

1962 • 60 citations

Spontaneous tension oscillations in guinea-pig atrial trabeculae

1975 • 59 citations

E-C COUPLING STUDIES ON SKINNED CARDIAC FIBERS

1978 • 58 citations

Ionic mechanisms of pacemaker activity in cardiac Purkinje fibers.

1978 • 54 citations

Electrophysiologic correlates of the inotropic effects of Isoproterenol in canine myocardium

1975 • 53 citations

TONUS CHANGES IN CARDIAC MUSCLE AND THEIR SIGNIFICANCE FOR THE INITIATION OF IMPULSES

1943 • 47 citations

Sustained spontaneous activity of ranvier nodes induced by the combined actions of TEA and lack of calcium

1968 • 37 citations

Calcium metabolism and active tension in mechanically disaggregated heart muscle

1974 • 36 citations

Arrhythmic movements of myocardial cells in culture and their improvement with antiarrhythmic drugs

1976 • 35 citations

Electrical and mechanical events in depolarized cardiac muscle fibers during low sodium perfusion

1971 • 29 citations

Ursachen und Ausl�sungsbedingungen von Myokard-Kontraktionen ohne regul�res Aktionspotential

1963 • 28 citations

Requirements for spontaneous contractility in isolated adult mammalian heart muscle cells

1971 • 27 citations

The sinus node: Structure, function, and clinical relevance

1980 • 26 citations

Spontaneous contractions of cultured heart cells in high K+ media

1969 • 24 citations

Simultaneously Recorded Oscillations in Membrane Potential and Isometric Contractile Force from Cardiac Muscle

1968 • 24 citations

CALCIUM IONS AND MEMBRANE CURRENT CHANGES INDUCED BY DIGITALIS IN CARDIAC PURKINJE FIBERS*

1978 • 24 citations

Ca-action potentials and contractions of heart muscle in Na-free solutions. Influence of caffeine.

1972 • 22 citations

Pacemaker Current in Frog Atrium

1972 • 19 citations

After-Contractions and Restitution of Contractility in the Isolated Guinea-Pig Auricles

1966 • 18 citations

[CAUSES AND CONDITIONS OF RELEASE OF MYOCARDIAL CONTRACTIONS WITHOUT A REGULAR ACTION POTENTIAL].

1963 • 16 citations

Mechanical and Electrical Oscillations in Cardiac Muscle of the Turtle

1973 • 14 citations

DIGITALIS: INOTROPIC AND ARRHYTHMOGENIC EFFECTS ON MEMBRANE CURRENTS IN CARDIAC PURKINJE FIBERS

1978 • 13 citations

Die isometrische Kontraktion des Meerschweinchen-Papillarmuskels in Abh�ngigkeit von der Calciumkonzentration und der Temperatur

1963 • 13 citations

Membrane Currents Underlying Rhythmic Activity in Frog Sinus Venosus

1978 • 6 citations

Electro-mechanical noise in atrial muscle fibres of the carp

1977 • 5 citations

Photoelectric Demonstration of Ouabain-Induced Arrhythmias in Single Isolated Myocardial Cells and in Cell Clusters <I>In Vitro</I>

1977 • 5 citations

Low-potassium inotropy in cardiac muscle [proceedings].

1978 • 2 citations

Deleted Work

1955 • 0 citations