The pathogenesis of choroidal neovascularization in patients with age-related macular degeneration.

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.

1989 • 1,282 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

1995 • 1,280 citations

Increased Vascular Endothelial Growth Factor Levels in the Vitreous of Eyes With Proliferative Diabetic Retinopathy

1994 • 1,269 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

1993 • 1,114 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization.

1995 • 1,021 citations

Age-related Macular Degeneration Histopathologic Studies

1993 • 747 citations

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1994 • 660 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman Primate

1996 • 638 citations

The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal diseases

1948 • 456 citations

Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases.

1995 • 425 citations

Essential Role of Growth Hormone in Ischemia-Induced Retinal Neovascularization

1997 • 394 citations

Detection of Vascular Endothelial Growth Factor Messenger RNA and Vascular Endothelial Growth Factor-like Activity in Proliferative Diabetic Retinopathy

1994 • 367 citations

Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor Are Present in Epiretinal and Choroidal Neovascular Membranes

1996 • 358 citations

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy.

1996 • 357 citations

The Beaver Dam Eye Study: The Relation of Age-related Maculopathy to Smoking

1993 • 333 citations

Relationship of Drusen and Abnormalities of the Retinal Pigment Epithelium to the Prognosis of Neovascular Macular Degeneration

1990 • 328 citations

Targeted Disruption of the FGF2 Gene Does Not Prevent Choroidal Neovascularization in a Murine Model

1998 • 324 citations

Foveolar choroidal blood flow in age-related macular degeneration.

1998 • 317 citations

Visual Results after Surgical Removal of Subfoveal Choroidal Neovascular Membranes

1994 • 312 citations

Midperipheral Fundus Involvement in Diabetic Retinopathy

1981 • 290 citations

Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells.

1987 • 286 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

1990 • 253 citations

Translocation of the Retina for Management of Subfoveal Choroidal Neovascularization II: A Preliminary Report in Humans

1998 • 239 citations

CLINICOPATHOLOGIC CORRELATION OF DRUSEN AND RETINAL PIGMENT EPITHELIAL ABNORMALITIES IN AGE-RELATED MACULAR DEGENERATION

2005 • 229 citations

A FUNDUS DYSTROPHY WITH UNUSUAL FEATURES (Late onset and dominant inheritance of a central retinal lesion showing oedema, haemorrhage and exudates developing into generalised choroidal atrophy with massive pigment proliferation)

1949 • 220 citations

Vascular endothelial growth factor expression in choroidal neovascularization in rats

1997 • 208 citations

Subretinal Neovascularization

1982 • 207 citations

Integrating with integrins.

1994 • 189 citations

Retinal Vascularization in Health and Disease

1957 • 189 citations

Role of hypoxia and extracellular matrix‐integrin binding in the modulation of angiogenic growth factors secretion by retinal pigmented epithelial cells

1999 • 167 citations

A New Model of Experimental Choroidal Neovascularization in the Rat

1989 • 164 citations

Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors.

1998 • 161 citations

Human Dermal Microvascular Endothelial Cells Produce Matrix Metalloproteinases in Response to Angiogenic Factors and Migration

1995 • 146 citations

Intravenous Infusion of Liposomal Benzoporphyrin Derivative for Photodynamic Therapy of Experimental Choroidal Neovascularization

1996 • 139 citations

Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.

1997 • 122 citations

CLINICOPATHOLOGIC CORRELATION OF CHOROIDAL NEOVASCULARIZATION DEMONSTRATED BY INDOCYANINE GREEN ANGIOGRAPHY IN A PATIENT WITH RETENTION OF GOOD VISION FOR ALMOST FOUR YEARS

1994 • 114 citations

Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.

1989 • 101 citations

A new model of subretinal neovascularization in the rabbit.

1995 • 82 citations

Expression of basic fibroblast growth factor mRNA in developing choroidal neovascularization

1996 • 75 citations

A Model of Subretinal Neovascularization in the Pigmented Rat

1989 • 73 citations

Sorsby's pseudoinflammatory macular dystrophy.

1981 • 71 citations

Integrin-dependent induction of early growth response genes in capillary endothelial cells

1996 • 66 citations

Insulin‐like Growth Factor I as an Angiogenic Agent In Vivo and In Vitro Studies

1993 • 61 citations

Neurotrophic Factors, Cytokines and Stress Increase Expression of Basic Fibroblast Growth Factor in Retinal Pigmented Epithelial Cells

1997 • 60 citations

Light-Induced Deposits in Bruch's Membrane of Protoporphyric Mice

1993 • 52 citations

Basic fibroblast growth factor experimentally induced choroidal angiogenesis in the minipig

1994 • 49 citations

Production of latent collagenase by human umbilical vein endothelial cells in response to angiogenic preparations

1985 • 38 citations

SUBRETINAL ENDOPHOTOCOAGULATION

1991 • 30 citations