Effects of spinal cholecystokinin receptor antagonists on morphine antinociception in a model of visceral pain in the rat.

Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity

1984 • 1,746 citations

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

1989 • 1,681 citations

Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemie myocardium

1985 • 994 citations

Two brain cholecystokinin receptors: implications for behavioral actions

1986 • 719 citations

Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat

1988 • 655 citations

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

1983 • 582 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas.

1992 • 398 citations

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin‐10 or antibodies to interleukin‐12

1996 • 358 citations

Potentiation of Opiate Analgesia and Apparent Reversal of Morphine Tolerance by Proglumide

1984 • 269 citations

Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat

1994 • 242 citations

Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint

1987 • 192 citations

Cholecystokinin and morphine analgesia: variations on a theme

1994 • 165 citations

Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide

1985 • 156 citations

Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation

1992 • 147 citations

The effect of carrageenan-induced inflammation on the sensitivity of unmyelinated skin nociceptors in the rat

1987 • 140 citations

Effects of kappa opioids in the inflamed rat colon

1999 • 138 citations

Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates

1985 • 136 citations

Sensitization of insensitive branches of C nociceptors in human skin.

1994 • 130 citations

A model of chronic pain in the rat: functional correlates of alterations in the activity of opioid systems

1987 • 116 citations

Increased release of immunoreactive cholecystokinin octapeptide by morphine and potentiation of μ-opioid analgesia by CCKB receptor antagonist L-365,260 in rat spinal cord

1993 • 108 citations

Co-localization of enkephalin and cholecystokinin in discrete areas of rat brain

1987 • 107 citations

Effects of kappa-opioid receptor agonists on responses to colorectal distension in rats with and without acute colonic inflammation.

1998 • 106 citations

Cholecystokinin as a factor in the enhanced potency of spinal morphine following carrageenin inflammation

1993 • 96 citations

Cholecystokinin B antagonists strongly potentiate antinociception mediated by endogenous enkephalins.

1994 • 90 citations

Ca2+ channel and adenylyl cyclase modulation by cloned mu-opioid receptors in GH3 cells.

1995 • 90 citations

Morphine-induced analgesia in the rat paw pressure test is blocked by CCK and enhanced by the CCK antagonist MK-329

1989 • 85 citations

Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception

1994 • 59 citations

Neuropeptide FF in the Rat Spinal Cord During Carrageenan Inflammation

1997 • 52 citations

The increase in morphine antinociceptive potency produced by carrageenan-induced hindpaw inflammation is blocked by naltrindole, a selective δ-opioid antagonist

1995 • 51 citations

Mobilization of calcium from intracellular stores as one of the mechanisms underlying the antiopioid effect of cholecystokinin octapeptide

1992 • 49 citations

Prevention of tolerance to the antinociceptive effects of systemic morphine by a selective cholecystokinin-B receptor antagonist in a rat model of peripheral neuropathy.

1997 • 46 citations

Naltrindole, an opioid δ antagonist, blocks the enhancement of morphine-antinociception induced by a CCKB antagonist in the rat

1994 • 45 citations

Cholecystokinin and its antagonist lorglumide respectively attenuate and facilitate morphine-induced inhibition of C-fiber evoked discharges of dorsal horn nociceptive neurons

1991 • 42 citations

Cholecystokinin and enkephalin in brain stem pain modulating circuits

1997 • 41 citations

Enhancement of morphine antinociception by a CCKB antagonist in mice is mediated via opioid delta receptors.

1996 • 39 citations

Visceral nociception: consequences, modulation and the future.

1995 • 34 citations

The effects of receptor selective opioid peptides on morphine-induced analgesia

1982 • 30 citations

Effect of CCK receptor antagonists on the antinociceptive, reinforcing and gut motility properties of morphine

1996 • 29 citations

Peripheral Opioid Analgesia: Mechanisms and Clinical Implications

1998 • 15 citations