Regional, metabolic, and circadian specificity of lateral hypothalamic orexin A feeding stimulation

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The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

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Orexin A activates locus coeruleus cell firing and increases arousal in the rat

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Fos Expression in Orexin Neurons Varies with Behavioral State

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Guiding principles for research involving animals and human beings

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Orexin (Hypocretin) Neurons Contain Dynorphin

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The hypocretins: Setting the arousal threshold

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Melanin-Concentrating Hormone Acutely Stimulates Feeding, But Chronic Administration Has No Effect on Body Weight

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The lateral hypothalamic area revisited: Ingestive behavior

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Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity

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Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action1This study was presented in part at the 28th Annual Meeting of the Society for Neuroscience, Los Angeles, CA, in November 1998.1

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Feeding response to central orexins

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Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat

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The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems

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Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia

1999 • 274 citations

Neurochemical Characterization of Hypothalamic Cocaine—Amphetamine-Regulated Transcript Neurons

1999 • 264 citations

Protein distribution of the orexin-2 receptor in the rat central nervous system

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Orexin-induced food intake involves neuropeptide Y pathway

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Neurotransmitter Regulation of Cellular Activation and Neuropeptide Gene Expression in the Paraventricular Nucleus of the Hypothalamus

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Hypothalamic cocaine- and amphetamine-regulated transcript (CART) neurons: histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide Y

1999 • 255 citations

Orexin receptor‐1 (OX‐R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake

2002 • 234 citations

Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation

2001 • 220 citations

Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight

1999 • 215 citations

Hypoglycemia Activates Orexin Neurons and Selectively Increases Hypothalamic Orexin-B Levels

2001 • 211 citations

Insulin-induced hypoglycemia increases preprohypocretin (orexin) mRNA in the rat lateral hypothalamic area

1999 • 186 citations

Diurnal variation in orexin A immunoreactivity and prepro-orexin mRNA in the rat central nervous system

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Feeding and activity induced by orexin A in the lateral hypothalamus in rats

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Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats

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Glucosensing neurons do more than just sense glucose

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A Commentary on the Neurobiology of the Hypocretin/Orexin System

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Both corticotropin releasing factor and neuropeptide Y are involved in the effect of orexin (hypocretin) on the food intake in rats

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Effects of orexins on energy balance and thermoregulation

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Orexin/hypocretin neurons: chemical phenotype and possible interactions with melanin-concentrating hormone neurons

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Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus

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Hypocretin I in the lateral hypothalamus activates key feeding-regulatory brain sites

2000 • 66 citations

Orexin A Preferentially Excites Glucose-Sensitive Neurons in the Lateral Hypothalamus of the Rat In Vitro

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Hypothalamic orexin-A-immunpositive neurons express Fos in response to central glucopenia

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Mammalian and Drosophila Blood: JAK of All Trades?

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Effects of restricted feeding on the activity of hypothalamic Orexin (OX)-A containing neurons and OX2 receptor mRNA level in the paraventricular nucleus of rats

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Processing of photic information within the intergeniculate leaflet of the lateral geniculate body: Assessed by neuropeptide Y immunoreactivity in the suprachiasmatic nucleus of rats

1993 • 54 citations

Interactions of neuropeptide Y, hypocretin-I (orexin A) and melanin-concentrating hormone on feeding in rats

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Addendum

1998 • 53 citations

Daily changes of neuropeptide Y-like immunoreactivity in the suprachiasmatic nucleus of the rat

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Cortical arousal induced by microinjection of orexins into the paraventricular nucleus of the rat

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Regional effect of naltrexone in the nucleus of the solitary tract in blockade of NPY-induced feeding

2000 • 51 citations