Spaceflight results in reduced mRNA levels for tissue-specific proteins in the musculoskeletal system

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Aviat space environ med

1992 • 5,078 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Inhibition of Bone Formation During Space Flight

1978 • 468 citations

Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.

1981 • 438 citations

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

1986 • 398 citations

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

1989 • 357 citations

Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats

1990 • 238 citations

The Temporal Response of Bone to Unloading*

1986 • 224 citations

Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading

1988 • 214 citations

Multiple ribosomal RNA cleavage pathways in mammalian cells

1981 • 190 citations

Structure of a full-length cDNA clone for the preproα2(I) chain of human type I procollagen. Comparison with the chicken gene confirms unusual patterns of gene conservation

1988 • 132 citations

Effects of Simulated Weightlessness on Bone Mineral Metabolism

1984 • 126 citations

The effects of immobilization on bone histomorphometry in rats

1986 • 101 citations

Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity.

1992 • 90 citations

Bone histomorphometric comparison of rat tibial metaphysis after 7-day tail suspension vs. 7-day spaceflight.

1991 • 81 citations

Effects of Spaceflight on Structural and Material Strength of Growing Bone

1983 • 80 citations

Loading‐related reorientation of bone proteoglycan in vivo. Strain memory in bone tissue?

1988 • 73 citations

Metabolic and morphologic properties of single muscle fibers in the rat after spaceflight, Cosmos 1887

1990 • 63 citations

Effects of spaceflight on rat humerus geometry, biomechanics, and biochemistry

1990 • 55 citations

Spaceflight Results in Formation of Defective Bone

1985 • 52 citations

Skeletal response to dietary calcium in a rat model simulating weightlessness

1986 • 48 citations

Bone maturation and quality of bone material in rats flown on the space shuttle 'Spacelab-3 Mission'.

1986 • 45 citations

Effect of microgravity on metabolic enzymes of individual muscle fibers

1990 • 41 citations

Absence of a growth hormone effect on rat soleus atrophy during a 4-day spaceflight

1993 • 40 citations

Report of the ad Hoc committee on nomenclature and standards for bone proteins and growth factors

1986 • 37 citations

Maturation of bone and dentin matrices in rats flown on the Soviet biosatellite Cosmos 1887

1990 • 35 citations

The effect of testosterone on skeletal muscle development and protein synthesis in rabbits.

1976 • 31 citations

Qualitative defects in natural killer cell function in ia osteopetrotic rats

1992 • 11 citations