Antitumor effects of synthetic VEGF-receptor binding antagonist, VGA1155.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (19)
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
2004 • 10,779 citations
The Biology of Vascular Endothelial Growth Factor
1997 • 4,359 citations
A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer
2003 • 2,723 citations
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
2003 • 1,939 citations
Molecular and biological properties of vascular endothelial growth factor
1999 • 1,174 citations
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.
1999 • 1,044 citations
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
2002 • 879 citations
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
2003 • 860 citations
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.
2000 • 848 citations
Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation.
2000 • 827 citations
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer.
2003 • 634 citations
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.
2000 • 501 citations
Clinical Experience with Angiogenesis Signaling Inhibitors: Focus on Vascular Endothelial Growth Factor (VEGF) Blockers
2002 • 268 citations
ZD4190: an orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy.
2000 • 195 citations
Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules.
1989 • 125 citations
Regional Effects of an Antivascular Endothelial Growth Factor Receptor Monoclonal Antibody on Receptor Phosphorylation and Apoptosis in Human 253J B-V Bladder Cancer Xenografts
2004 • 55 citations
Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses
1989 • 42 citations
A novel low molecular weight antagonist of vascular endothelial growth factor receptor binding: VGA1155.
2003 • 23 citations
VGA1155, a novel binding antagonist of VEGF, inhibits angiogenesis in vitro and in vivo.
2004 • 15 citations