Phase I study of multiple dose intramuscularly administered recombinant gamma interferon.

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

1983 • 1,918 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

CELLULAR RESISTANCE TO INFECTION

1962 • 1,422 citations

Alpha Interferon for Induction of Remission in Hairy-Cell Leukemia

1984 • 833 citations

Expression of human immune interferon cDNA in E. coli and monkey cells

1982 • 703 citations

Evidence that types I and II interferons have different receptors

1981 • 511 citations

Leukocyte Interferon-Induced Tumor Regression in Human Metastatic Breast Cancer, Multiple Myeloma, and Malignant Lymphoma

1980 • 503 citations

Convenient assay for interferons

1981 • 486 citations

Recombinant Leukocyte A Interferon: Pharmacokinetics, Single-Dose Tolerance, and Biologic Effects in Cancer Patients

1982 • 381 citations

Leukocyte interferon-induced myeloid cytoreduction in chronic myelogenous leukemia

1983 • 337 citations

Renal cell carcinoma: antitumor effects of leukocyte interferon.

1983 • 320 citations

Differential efficacies of human type I and type II interferons as antiviral and antiproliferative agents.

1980 • 286 citations

Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation.

1984 • 276 citations

Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons

1984 • 260 citations

γ-Interferon is one of several direct B cell-maturing lymphokines

1984 • 237 citations

Mechanisms of fever induced by recombinant human interferon.

1984 • 228 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

Pharmacokinetics, single-dose tolerance, and biological activity of recombinant gamma-interferon in cancer patients.

1985 • 185 citations

Interferon induced in human leukocytes by mitogens: production, partial purification and characterization

1980 • 137 citations

THYMUS-DERIVED LYMPHOCYTES PRODUCE AN IMMUNOLOGICALLY SPECIFIC MACROPHAGEARMING FACTOR

1972 • 128 citations

Immunological characterization of homosexual males.

1983 • 108 citations

Gamma interferon (IFN gamma) and IFN alpha/beta suppress murine myeloid colony formation (CFU-C)N: magnitude of suppression is dependent upon level of colony-stimulating factor (CSF).

1982 • 107 citations

Interferons: biochemical, cell growth inhibitory, and immunological effects.

1981 • 103 citations

ANTIBODIES TO HUMAN LEUCOCYTE INTERFERONS IN CANCER PATIENTS

1983 • 103 citations

Human Leukocyte Interferon to Control Thrombocytosis in Chronic Myelogenous Leukemia

1983 • 91 citations

Pharmacokinetic study of partially pure gamma-interferon in cancer patients.

1984 • 74 citations

Towards tumor therapy with interferons, part II. Interferons: in vivo effects

1980 • 63 citations

Serum lysozyme: an index of macrophage function.

1979 • 52 citations

Effect of the recreational agent isobutyl nitrite on human peripheral blood leukocytes and on in vitro interferon production.

1983 • 33 citations

Two monoclonal antibodies (OKIa1 and OKT10) for the study of the final B cell maturation.

1982 • 27 citations

Leukocyte subset analysis and related immunological findings in acquired immunodeficiency disease syndrome (AIDS) and malignancies.

1983 • 23 citations

A phase I study of recombinant interferon gamma administered by s.c. injection three times per week in patients with solid tumours

1987 • 23 citations