The Fate of Pancreatic Islets Transplanted into Diabetic Mice Is Dependent on Their Genetic Background

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Some statistical methods useful in circulation research.

1980 • 3,978 citations

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

1978 • 1,274 citations

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.

1983 • 466 citations

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability.

1985 • 292 citations

Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets

1978 • 287 citations

Inhibitory Effects of Interleukin 1 on Insulin Secretion, Insulin Biosynthesis, and Oxidative Metabolism of Isolated Rat Pancreatic Islets*

1987 • 278 citations

Diabetogenic Effect of Streptozotocin in the Rat During the Perinatal Period

1974 • 232 citations

Islet Secretion in a New Experimental Model for Non-insulin-dependent Diabetes

1981 • 232 citations

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA.

1985 • 196 citations

Genetic Influence of the Streptozotocin-induced Insulitis and Hyperglycemia

1977 • 153 citations

The genetics of diabetes susceptibility in mice

1989 • 134 citations

Experimental reduction of B‐cell mass: Implications for the pathogenesis of diabetes

1986 • 134 citations

Severe Diabetes Induced in Subtotally Depancreatized Dogs by Sustained Hyperglycemia

1988 • 113 citations

LARGE-SCALE PRODUCTION OF FETAL PORCINE PANCREATIC ISLETLIKE CELL CLUSTERS

1988 • 112 citations

Construction and selection of recombinant plasmids containing full-length complementary DNAs corresponding to rat insulins I and II.

1979 • 110 citations

Hexose metabolism in pancreatic islets. Feedback control of d-glucose oxidation by functional events

1988 • 105 citations

Effects of Hyperglycemia on Function of Isolated Mouse Pancreatic Islets Transplanted Under Kidney Capsule

1989 • 101 citations

Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets

1982 • 92 citations

Type II Diabetes, Glucose “Non-Sense,” and Islet Desensitization

1989 • 89 citations

Effect of genetic background on the capacity for islet cell replication in mice

1984 • 81 citations

Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus.

1990 • 76 citations

Impaired Insulin Secretion Associated With Near Normoglycemia: Study in Normal Rats With 96-h In Vivo Glucose Infusions

1987 • 73 citations

Molecular Mimicry Between Insulin and Retroviral Antigen p73: Development of Cross-Reactive Autoantibodies in Sera of NOD and C57BL/KsJ db/db Mice

1988 • 68 citations

Functional Characteristics of Rat Pancreatic Islets Maintained in Culture After Exposure to Human Interleukin 1

1988 • 60 citations

Quantitative Analysis of Pancreatic Proinsulin mRNA in Genetically Diabetic (db/db) Mice

1987 • 58 citations

Preferential Reduction of Insulin Production in Mouse Pancreatic Islets Maintained in Culture after Streptozotocin Exposure*

1988 • 57 citations

Evolution of Abnormal Insulin Secretory Responses During 48-h In Vivo Hyperglycemia

1988 • 56 citations

Long-term effects of glucose on insulin release and glucose oxidation by mouse pancreatic islets maintained in tissue culture

1974 • 53 citations

Blood flow measurements in autotransplanted pancreatic islets of the rat. Impairment of the blood perfusion of the graft during hyperglycemia.

1987 • 50 citations

Insulin Production and Glucose Metabolism in Isolated Pancreatic Islets of Rats With NIDDM

1988 • 50 citations

Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations

1988 • 49 citations

Glucose induces intracisternal type A retroviral gene transcription and translation in pancreatic beta cells.

1986 • 48 citations

Modulation of proinsulin messenger RNA after partial pancreatectomy in rats. Relationships to glucose homeostasis.

1985 • 47 citations

Interleukin-1 Inhibits Glucose-Modulated Insulin and Glucagon Secretion in Rat Islet Monolayer Cultures*

1988 • 45 citations

Effects of D-glucose, L-leucine, and 2-ketoisocaproate on Insulin mRNA Levels in Mouse Pancreatic Islets

1986 • 31 citations

Hexose metabolism in pancreatic islets stimulation by d-glucose of [2-3H]glycerol detritiation

1988 • 21 citations

Can desensitization of the B-cell to D-glucose be simulated in cultured pancreatic islets?

1987 • 18 citations

ANALYSIS OF DIFFERENTIAL SURVIVAL OF SYNGENEIC ISLETS TRANSPLANTED INTO HYPERGLYCEMIC C57BL/6J VERSUS C57BL/KsJ MICE

1987 • 17 citations

Sustained exposure of toxically damaged mouse pancreatic islets to high glucose does not increase β-cell dysfunction

1989 • 15 citations