Maitotoxin and P2Z/P2X₇purinergic receptor stimulation activate a common cytolytic pore

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

1996 • 1,703 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

1997 • 1,218 citations

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

1995 • 988 citations

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

1994 • 924 citations

The Permeabilizing ATP Receptor, P2X7

1997 • 486 citations

Hetero-oligomeric Assembly of P2X Receptor Subunits

1999 • 411 citations

Pore dilation of neuronal P2X receptor channels

1999 • 408 citations

ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes.

1987 • 407 citations

Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds

1999 • 355 citations

Extracellular ATP as a trigger for apoptosis or programmed cell death.

1991 • 342 citations

The Mammalian Degenerin MDEG, an Amiloride-sensitive Cation Channel Activated by Mutations Causing Neurodegeneration in Caenorhabditis elegans

1996 • 317 citations

The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans

1990 • 304 citations

The Shape of Cell Death

1997 • 302 citations

The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role.

1995 • 251 citations

Mechanisms of Cell Death Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Acute Excitotoxic Necrosis and Delayed Apoptosis

1997 • 250 citations

Characterization of the Bradykinin-stimulated Calcium Influx Pathway of Cultured vascular Endothelial Cells

1989 • 224 citations

Characterization of Recombinant Human P2X₄ Receptor Reveals Pharmacological Differences to the Rat Homologue

1997 • 220 citations

Isoquinolines as Antagonists of the P2X₇Nucleotide Receptor: High Selectivity for the Human versus Rat Receptor Homologues

1998 • 218 citations

Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line.

1996 • 190 citations

Different Sensitivities to pH of ATP-Induced Currents at Four Cloned P2X Receptors

1997 • 181 citations

Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes.

1994 • 168 citations

Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X₇receptors

1998 • 157 citations

Modulation of P2X7 nucleotide receptor expression by pro- and anti-inflammatory stimuli in THP-1 monocytes

1998 • 149 citations

Maitotoxin: A unique pharmacological tool for research on calcium-dependent mechanisms

1990 • 144 citations

ATP-induced pore formation in the plasma membrane of rat peritoneal mast cells.

1990 • 120 citations

Molecular characterization and pharmacological properties of the human P2X3 purinoceptor

1997 • 105 citations

Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X₇channel

1998 • 103 citations

Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases

1999 • 91 citations

Maitotoxin activates a nonselective cation channel and a P2Z/P2X₇-like cytolytic pore in human skin fibroblasts

1999 • 68 citations

Apoptosis and cell death in neuronal cells: where does Ca2+ fit in?

1998 • 57 citations

Maitotoxin activates a nonselective cation channel and stimulates Ca2+ entry in MDCK renal epithelial cells.

1994 • 51 citations

Selective stimulation of Ca2+ flux in cells by maitotoxin

1992 • 45 citations

Maitotoxin (MTX) activates a nonselective cation channel in Xenopus laevis oocytes

1998 • 45 citations

Maitotoxin-elicited calcium influx in cultured cells

1995 • 45 citations

Characterization of Excitatory Amino Acid Neurotoxicity in N‐methyl‐D‐aspartate Receptor‐deficient Mouse Cortical Neuronal Cells

1996 • 28 citations

Characterization of the maitotoxin-induced calcium influx pathway from human skin fibroblasts

1997 • 22 citations

Maitotoxin-induced myocardial cell injury: Calcium accumulation followed by ATP depletion precedes cell death

1990 • 22 citations

Maitotoxin-induced liver cell death involving loss of cell ATP following influx of calcium

1989 • 17 citations

Maitotoxin, a novel activator of mediator release from human basophils, induces large increases in cytosolic calcium resulting in histamine, but not leukotriene C4, release.

1992 • 8 citations

Suckers from the Apple Tree

1870 • 4 citations