Complex Chromosome Exchanges Induced by Gamma Rays in Human Lymphocytes: An mFISH Study

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Karyotyping human chromosomes by combinatorial multi-fluor FISH

1996 • 1,265 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

The theory of dual radiation action

1974 • 638 citations

Classification and relationships of induced chromosomal structual changes.

1976 • 444 citations

AN ANALYSIS OF X-RAY INDUCED CHROMOSOMAL ABERRATIONS IN TRADESCANTIA

1940 • 411 citations

The mechanism of the induction by radiation of chromosome aberrations inTradescantia

1942 • 402 citations

Current status of cytogenetic procedures to detect and quantify previous exposures to radiation

1988 • 360 citations

CHROMOSOME ABERRATIONS INDUCED BY X-RAYS

1938 • 342 citations

A proposed system for scoring structural aberrations detected by chromosome painting

1995 • 290 citations

Actions of radiations on living cells. 2nd edition

1956 • 199 citations

Fish “painting” patterns resulting from complex exchanges

1994 • 190 citations

Rapid Human Chromosome Aberration Analysis Using Fluorescencein SituHybridization

1989 • 182 citations

Analysis of human lymphocyte cell cycle time in culture measured by sister chromatid differential staining

1977 • 169 citations

Frequencies of X-ray-induced Chromosome Translocations in Human Peripheral Lymphocytes as Detected byin SituHybridization Using Chromosome-specific DNA Libraries

1992 • 162 citations

Validation of Chromosome Painting as a Biodosimeter in Human Peripheral Lymphocytes Following Acute Exposure to Ionizing Radiationin Vitro

1993 • 150 citations

Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations

1991 • 148 citations

Radiation-induced Chromosome Aberrations Analysed by Two-colour Fluorescencein SituHybridization with Composite Whole Chromosome-specific DNA Probes and a Pancentromeric DNA Probe

1993 • 146 citations

Rapid metaphase and interphase detection of radiation‐induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization

1990 • 140 citations

Radiation-induced Chromosome Aberrations Analysed by Fluorescencein SituHybridization with a Triple Combination of Composite Whole Chromosome-specific DNA Probes

1992 • 131 citations

Analyzing Radiation-Induced Complex Chromosome Rearrangements by Combinatorial Painting¹

2001 • 130 citations

An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH)

1998 • 126 citations

Fluorescencein SituHybridization Detection of Chromosomal Aberrations in Human Lymphocytes: Applicability to Biological Dosimetry

1995 • 118 citations

Identification withGandRBanding of the Position of Breakage Points Induced in Human Chromosomes byin VitroX-irradiation

1976 • 114 citations

On the scoring of FISH-“painted” chromosome-type exchange aberrations

1994 • 105 citations

Ionizing Radiation Damage and Its Early Development in Chromosomes

1993 • 101 citations

The Rejoining of DNA Double-strand Breaks and a Model for the Formation of Chromosomal Rearrangements

1978 • 95 citations

Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected using fluorescence in situ hybridization

1996 • 88 citations

Radiation-Induced Damage, Repair and Exchange Formation in Different Chromosomes of Human Fibroblasts Determined by Fluorescence In Situ Hybridization

1994 • 87 citations

Using three-color chromosome painting to test chromosome aberration models.

1993 • 84 citations

Analysis for DNA-proportional Distribution of Radiation-induced Chromosome Aberrations in Various Triple Combinations of Human Chromosomes Using Fluorescencein SituHybridization

1994 • 82 citations

A Comparison of the Yields of Translocations and Dicentrics Measured Using Fluorescencein SituHybridization

1993 • 80 citations

Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe

1998 • 79 citations

Frequency and distribution studies of asymmetrical versus symmetrical chromosome aberrations

1982 • 78 citations

Estimating the True Frequency of X-ray-induced Complex Chromosome Exchanges Using Fluorescencein SituHybridization

1995 • 76 citations

Assignment of aberration breakpoints in banded chromosomes

1977 • 76 citations

Mechanisms of induction of chromosomal aberrations and their detection by fluorescence in situ hybridization

1996 • 74 citations

Estimate of true incomplete exchanges using fluorescence in situ hybridization with telomere probes

1998 • 69 citations

Rapid detection of radiation-induced chromosomal aberrations in lymphocytes and hematopoietic progenitor cells by mFISH

2000 • 63 citations

Validation of Chromosome Painting. II. A Detailed Analysis of Aberrations Following High Doses of Ionizing Radiationin Vitro

1995 • 59 citations

Estimation of minimal size of translocated chromosome segments detectable by fluorescence in situ hybridization

1997 • 58 citations

Frequency of Reciprocal Translocations and Dicentrics Induced in Human Blood Lymphocytes by X-irradiation as Determined by Fluorescencein SituHybridization

1993 • 57 citations

Radiation-induced breakpoint misrejoining in human chromosomes: random or non-random?

1999 • 51 citations

Visualization of Nonreciprocal Chromosome Exchanges in Irradiated Human Fibroblasts by Fluorescence In Situ Hybridization

1993 • 51 citations

Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblasts in vitro detected using FISH

1998 • 50 citations

The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage

1991 • 47 citations

X-ray Biological Dosimetry Performed by Selective Painting of Human Chromosomes 1 and 2

1995 • 46 citations

The 60Co gamma ray dose-response for chromosomal aberrations in human lymphocytes analysed by FISH; applicability to biological dosimetry

1999 • 45 citations

Mechanism of chromosome exchange formation in human fibroblasts: Insights from “chromosome painting”

1993 • 41 citations

Clustering of radiation-produced breaks along chromosomes: modelling the effects on chromosome aberrations

1999 • 38 citations

Theoretical predictions on the equality of radiation-produced dicentrics and translocations detected by chromosome painting

1996 • 37 citations

X-ray-induced simple, pseudosimple and complex exchanges involving two distinctly painted chromosomes

1999 • 35 citations

Analysis by FISH of the spectrum of chromosome aberrations induced by X-rays in G0 human lymphocytes and their fate through mitotic divisions in culture

1999 • 29 citations

Identification of X-ray-induced Complex Chromosome Exchanges Using Fluorescencein SituHybridization: A Comparison at Two Doses

1994 • 26 citations

Ultrasoft 1.5 keV Aluminum K X Rays Are Efficient Producers of Complex Chromosome Exchange Aberrations as Revealed by Fluorescence In Situ Hybridization

1996 • 22 citations

Radiation induced chromosome aberrations: some biophysical considerations

1998 • 12 citations