Pooling Research Results: Benefits and Limitations of Meta-Analysis

Bias in meta-analysis detected by a simple, graphical test

1997 • 47,526 citations

Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials

1995 • 5,696 citations

Empirical Evidence of Bias

1995 • 5,260 citations

Improving the quality of reporting of randomized controlled trials. The CONSORT statement

1996 • 3,395 citations

Publication bias in clinical research

1991 • 3,034 citations

Improving the Quality of Reporting of Randomized Controlled Trials

1996 • 2,811 citations

Quantitative Synthesis in Systematic Reviews

1997 • 2,428 citations

A Comparison of Results of Meta-analyses of Randomized Control Trials and Recommendations of Clinical Experts

1992 • 1,451 citations

Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklists

1995 • 1,323 citations

Meta-Analyses of Randomized Controlled Trials

1987 • 1,278 citations

Review papers : The statistical basis of meta-analysis

1993 • 1,221 citations

Discrepancies between Meta-Analyses and Subsequent Large Randomized, Controlled Trials

1997 • 1,207 citations

Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

1992 • 1,132 citations

The Medical Review Article: State of the Science

1987 • 859 citations

Publication bias: the case for an international registry of clinical trials.

1986 • 750 citations

The Cochrane Collaboration

1995 • 698 citations

Do Certain Countries Produce Only Positive Results? A Systematic Review of Controlled Trials

1998 • 678 citations

Summing up evidence: one answer is not always enough

1998 • 671 citations

Effect of the Statistical Significance of Results on the Time to Completion and Publication of Randomized Efficacy Trials

1998 • 628 citations

Invited Commentary: Ecologic Studies—Biases, Misconceptions, and Counterexamples

1994 • 479 citations

Practical methodology of meta‐analyses (overviews) using updated individual patient data

1995 • 472 citations

Cholesterol lowering and mortality: the importance of considering initial level of risk.

1993 • 431 citations

The Cochrane Collaboration. Preparing, maintaining, and disseminating systematic reviews of the effects of health care

1995 • 381 citations

Large Trials vs Meta-analysis of Smaller Trials

1996 • 337 citations

Assessing possible hazards of reducing serum cholesterol

1994 • 316 citations

Issues in Comparisons Between Meta-analyses and Large Trials

1998 • 251 citations

An empirical study of the possible relation of treatment differences to quality scores in controlled randomized clinical trials

1990 • 250 citations

Predictive ability of meta-analyses of randomised controlled trials

1995 • 232 citations

An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials

1998 • 213 citations

Discordance between Meta-analyses and Large-Scale Randomized, Controlled Trials: Examples from the Management of Acute Myocardial Infarction

1995 • 129 citations

Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis

1998 • 126 citations

Clinical Efficacy of High-Dose Acyclovir in Patients with Human Immunodeficiency Virus Infection: A Meta-Analysis of Randomized Individual Patient Data

1998 • 116 citations

The impact of high-risk patients on the results of clinical trials

1997 • 112 citations

Keynote addresses. Meta‐analysis: Reconciling the results of independent studies

1995 • 86 citations

Meta-analysis: Science or religion?

1989 • 54 citations

Caution: should we be treating HIV infection early?

1998 • 50 citations

Uncontrolled Pearls, Controlled Evidence, Meta-Analysis and the Individual Patient☆

1998 • 23 citations

Relationship Between Event Rates and Treatment Effects in Clinical Site Differences Within Multicenter Trials

1999 • 9 citations

Evaluation of guidelines for initiation of highly active antiretroviral therapy in a longitudinal cohort of HIV-infected individuals

1998 • 9 citations