Thiamin and the Brain

SUBACUTE NECROTIZING ENCEPHALOMYELOPATHY IN AN INFANT

1951 • 761 citations

Wernicke's Encephalopathy

1985 • 428 citations

Abnormality of a Thiamine-Requiring Enzyme in Patients with Wernicke-Korsakoff Syndrome

1977 • 397 citations

Cytochrome c oxidase deficiency in leigh syndrome

1987 • 368 citations

The incidence of Wernicke's encephalopathy in Australia--a neuropathological study of 131 cases.

1983 • 343 citations

[6] Preparation of synaptic and nonsynaptic mitochondria from mammalian brain

1979 • 294 citations

Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces

1975 • 242 citations

Synthese des Vitamin A

1947 • 226 citations

The Effect of Thiamine Deficiency on the Activity of Erythrocyte Hemolysate Transketolase

1960 • 204 citations

The Genetic Heterogeneity of Lactic Acidosis: Occurrence of Recognizable Inborn Errors of Metabolism in a Pediatric Population with Lactic Acidosis

1980 • 169 citations

Cerebral glucose use measured with [14C]glucose labeled in the 1, 2, or 6 position

1985 • 168 citations

The role of thiamine in nervous tissue

1979 • 160 citations

Defective activation of the pyruvate dehydrogenase complex in subacute necrotizing encephalomyelopathy (leigh disease)

1979 • 146 citations

The neurology of aging

1983 • 135 citations

Biochemical Alterations in Thiamine Deficiency—Their Interpretation

1967 • 130 citations

Development of mitochondrial energy metabolism in rat brain

1977 • 127 citations

Low Energy Levels in Thiamine-Deficient Encephalopathy

1984 • 110 citations

The induction and reversibility of cerebral acidosis in thiamine deficiency

1984 • 99 citations

Ultrastructural features of early brain stem lesions of thiamine-deficient rats.

1968 • 96 citations

Clinical Chemistry of Thiamin

1983 • 94 citations

The effect of thiamine deficiency on the pyruvate decarboxylase system of the central nervous system

1965 • 91 citations

Kinetics of thiamine transport across the blood‐brain barrier in the rat.

1982 • 88 citations

Severe Acute Metabolic Acidosis (Acute Beriberi): An Avoidable Complication of Total Parenteral Nutrition

1985 • 79 citations

A new chromatographic method for the determination of thiamine and its mono-, di- and tri-phosphates in animal tissues

1961 • 78 citations

Enzyme‐inhibiting factor in subacute necrotizing encephalomyelopathy

1969 • 72 citations

Widespread neuroanatomical damage and learning deficits following chronic alcohol consumption or vitamin-B1 (thiamine) deficiency in rats

1983 • 72 citations

THE EFFECT OF THIAMINE DEFICIENCY ON THE ACETYLCOENZYMEA AND ACETYLCHOLINE LEVELS IN THE RAT BRAIN

1973 • 70 citations

Neurochemical pathology in Korsakoff's psychosis: Implications for other cognitive disorders

1984 • 66 citations

Thiamine intestinal transport

1972 • 64 citations

Transport in the Central Nervous System

1971 • 59 citations

The Rate of Utilization of Glucose Via Hexosemonophosphate Shunt in Brain

1983 • 59 citations

BERIBERI CAUSED BY ANTITHIAMIN FACTORS IN FOOD AND ITS PREVENTION*

1982 • 57 citations

CONTRIBUTION OF THE PENTOSE CYCLE TO THE METABOLISM OF GLUCOSE IN THE ISOLATED, PERFUSED BRAIN OF THE MONKEY

1970 • 57 citations

Malabsorption of Thiamin in Folate-deficient Rats

1974 • 57 citations

Observations on the Mechanism of Thiamine Hydrochloride Absorption in Man

1972 • 56 citations

Fine structure of the early changes in the vestibular nuclei of the thiamine-deficient rat.

1968 • 56 citations

Thiamine transport in the central nervous system

1976 • 56 citations

Pyruvate Decarboxylase Deficiency in Subacute Necrotizing Encephalomyelopathy

1981 • 53 citations

A study of partial thiamin restriction in human volunteers

1980 • 50 citations

Thiamine as an integral component of brain synaptosomal membranes.

1981 • 50 citations

SOME REGIONAL PATHOLOGIC AND METABOLIC CONSEQUENCES IN MOUSE BRAIN OF PYRITHIAMINE-INDUCED THIAMINE DEFICIENCY

1970 • 49 citations

Autoradiographic demonstration of loss of labeled indoleamine axons of the cerebellum in chronic diet-induced thiamine deficiency

1977 • 48 citations

Intermittent thiamine deficiency in the rhesus monkey. II. Evidence for memory loss

1983 • 47 citations

Thiamine deficiency in the cat leads to severe learning deficits and to widespread neuroanatomical damage

1982 • 44 citations

PRODUCTION OF ACETYLCHOLINE IN RAT BRAIN FOLLOWING THIAMINE DEPRIVATION AND TREATMENT WITH THIAMINE ANTAGONISTS¹²

1969 • 43 citations

Persisting nutritional neuropathy amongst former war prisoners.

1982 • 43 citations

Thiamine Release from Nerve Membranes by Tetrodotoxin

1969 • 42 citations

Thiamine‐responsive inborn errors of metabolism

1985 • 42 citations

Effects of Thiamin Deficiency on Acetylcholine Levels and Utilization in vivo in Rat Brain

1977 • 40 citations

Wernicke's encephalopathy after gastric partitioning for morbid obesity.

1984 • 37 citations

Normal levels of acetyl coenzyme A and of acetylcholine in the brains of thiamin‐deficient rats¹

1975 • 35 citations

CHEMICAL AND CLINICAL FINDINGS IN BERI-BERI WITH SPECIAL REFERENCE TO VITAMIN B<sub>1</sub> DEFICIENCY<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1936 • 35 citations

SO-CALLED BREAST MILK INTOXICATION

1934 • 35 citations

Necrotizing Encephalomyelopathy of Leigh: Neuropathological Findings in 8 Cases

1970 • 34 citations

RICE AND BERI-BERI:

1907 • 33 citations

ANTITHIAMINS OF PLANT ORIGIN: THEIR CHEMICAL NATURE AND MODE OF ACTION

1982 • 33 citations

THE FLUORESCENT MICROSCOPIC LOCALIZATION OF THIAMINE IN NERVOUS TISSUE

1968 • 31 citations

Cerebellar degeneration in thiamine-deficient rats.

1970 • 30 citations

THE QUANTITATIVE HISTOCHEMICAL DISTRIBUTION OF THIAMINE IN NORMAL RAT BRAIN*

1959 • 30 citations

Kinetic Studies of Mouse Brain Transketolase

1982 • 28 citations

Faecal thiaminase in clinically normal sheep associated with outbreaks of polioencephalomalacia

1977 • 28 citations

TRANSKETOLASE VARIANT ENZYMES AND BRAIN DAMAGE

1985 • 27 citations

GABA-transaminase and glutamic acid decarboxylase changes in the brain of rats treated with pyrithiamine

1985 • 26 citations

Experimentally induced thiamine deficiency in beagle dogs: pathologic changes of the central nervous system.

1986 • 25 citations

THE HEXOSE MONOPHOSPHATE PATHWAY IN ETHYLNITROSOUREA INDUCED TUMORS OF THE NERVOUS SYSTEM

1978 • 24 citations

Infantile beriberi presenting as subacute necrotizing encephalomyelopathy

1987 • 24 citations

BRAIN LIPID COMPOSITION OF IMMATURE THIAMINE‐DEFICIENT AND UNDERNOURISHED RATS¹

1975 • 24 citations

THE ROLE OF THIAMIN IN MAPLE SYRUP URINE DISEASE*

1982 • 23 citations

THE HISTORY OF THIAMINE

1962 • 21 citations

NEUROMUSCULAR AND GANGLIONIC BLOCKING ACTION OF THIAMINE AND ITS DERIVATIVES

1958 • 19 citations

Leigh's necrotizing encephalopathy with pyruvate carboxylase deficiency.

1983 • 19 citations

MECHANISM OF ACTION OF THIAMINE DIPHOSPHATE IN ENZYMIC REACTIONS*

1962 • 19 citations

Local cerebral glucose utilization in the symptomatic thiamine‐deficient rat

1982 • 19 citations

THE AXOPLASMIC TRANSPORT OF THIAMINE IN RAT SCIATIC NERVE

1973 • 18 citations

Increased axonal transport in peripheral nerves of thiamine-deficient rats

1987 • 18 citations

Blood pyruvic and α-ketoglutaric acids in thiamine deficiency

1965 • 17 citations

Thiamine deficiency encephalopathy in the developing rat

1974 • 16 citations

Biogenesis of Cocarboxylase in Escherichia coli

1972 • 16 citations

PROBLEMS OF THIAMINE DEFICIENCY STATES AND THEIR AMELIORATION

1962 • 13 citations

Catecholamine accumulation in tissues of thiamine-deficient rats after inhibition of monoamine oxidase

1970 • 13 citations

DIFFERENTIAL DETERMINATION OF THIAMINE AND ITS PHOSPHATES, HYDROXYETHYLTHIAMINE AND PYRITHIAMINE, IN RAT BRAIN

1973 • 11 citations

The etiology of beri-beri

2012 • 9 citations

Effect of diet-induced thiamine deficiency on visceral DNA synthesis and tissue composition

1976 • 9 citations

The effect of thiamine deficiency in rats and pigeons on the content of materials with acetylcholine-like activity in brain, heart and skeletal muscle.

1966 • 9 citations

EXPERIENCE IN THE ETIOLOGY AND PREVENTION OF THIAMINE DEFICIENCY IN THE PHILIPPINE ISLANDS

1962 • 8 citations

Beriberi and Scurvy

1915 • 7 citations

Axonal transport of thiamine in frog sciatic nerves in vitro

1983 • 6 citations

elevated thiamine levels in SIDS, non-SIDS, and adults: Postmortem artifact

1984 • 6 citations

A biochemical and immunohistochemical study of central serotonin nerves in rats with chronic thiamine deficiency

1983 • 6 citations

STUDIES ON ENZYMATIC SYNTHESIS OF COCARBOXYLASE IN ANIMAL TISSUE:IV. EFFECT OF METALLIC IONS, VARIOUS NUCLEOTIDES AND THIAMINE DERIVATIVES ON THIAMINOKINASE FROM RAT LIVER

1960 • 5 citations

High incidence of subclinical hypovitaminosis of B1 among university students founds by a field study in Ehime, Japan.

1981 • 3 citations

Thiamine non‐responsive intermittent branched‐chain ketoaciduria in a laotian child

1986 • 1 citations