The Future of Antifungal Therapy

A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation

1992 • 1,179 citations

Increase inCandida kruseiInfection among Patients with Bone Marrow Transplantation and Neutropenia Treated Prophylactically with Fluconazole

1991 • 957 citations

Antifungal and Surgical Treatment of Invasive Aspergillosis: Review of 2,121 Published Cases

1990 • 918 citations

Resistance of Candida species to fluconazole

1995 • 890 citations

Hospital-Acquired Candidemia

1988 • 835 citations

Candidemia in a Tertiary Care Hospital: Epidemiology, Risk Factors, and Predictors of Mortality

1992 • 698 citations

Disseminated Histoplasmosis in the Acquired Immune Deficiency Syndrome

1990 • 645 citations

Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis

1992 • 628 citations

Oral Azole Drugs as Systemic Antifungal Therapy

1994 • 583 citations

Disseminated Penicillium marneffei infection in Southeast Asia

1994 • 582 citations

Importance of Candida Species Other than C. albicans as Pathogens in Oncology Patients

1995 • 562 citations

NIAID mycoses study group multicenter trial of oral itraconazole therapy for invasive aspergillosis

1994 • 459 citations

Cryptococcal Meningitis in Patients with AIDS

1988 • 400 citations

Hepatic Candidiasis in Cancer Patients: The Evolving Picture of the Syndrome

1988 • 390 citations

Association of Torulopsis glabrata infections with fluconazole prophylaxis in neutropenic bone marrow transplant patients

1993 • 352 citations

Fluconazole Compared with Amphotericin B plus Flucytosine for Cryptococcal Meningitis in AIDS

1990 • 345 citations

A Randomized Trial Comparing Fluconazole with Clotrimazole Troches for the Prevention of Fungal Infections in Patients with Advanced Human Immunodeficiency Virus Infection

1995 • 324 citations

Pharmacokinetics of itraconazole following oral administration to normal volunteers

1988 • 285 citations

Efficacy of amphotericin B encapsulated in liposomes (AmBisome) in the treatment of invasive fungal infections in immunocompromised patients

1991 • 281 citations

Cryptococcal Meningitis and AIDS

1993 • 280 citations

Resistance of Candida albicans to Fluconazole During Treatment of Oropharyngeal Candidiasis in a Patient with AIDS: Documentation by In Vitro Susceptibility Testing and DNA Subtype Analysis

1994 • 271 citations

Liposomal and Lipid Formulations of Amphotericin B

1992 • 269 citations

Comparative and collaborative evaluation of standardization of antifungal susceptibility testing for filamentous fungi

1995 • 252 citations

Estimation of the Prevalence of Cryptococcal Infection Among Patients Infected with the Human Immunodeficiency Virus in New York City

1994 • 249 citations

Itraconazole treatment of disseminated histoplasmosis in patients with the acquired immunodeficiency syndrome

1995 • 240 citations

Infections Caused by Penicillium marneffei in China and Southeast Asia: Review of Eighteen Published Cases and Report of Four More Chinese Cases

1988 • 238 citations

Liposomal amphotericin B (AmBisome): safety data from a phase II/III clinical trial

1991 • 236 citations

Progressive disseminated histoplasmosis in patients with acquired immunodeficiency syndrome

1988 • 233 citations

Antibodies Elicited by a Cryptococcus neoformans-Tetanus Toxoid Conjugate Vaccine Have the Same Specificity as Those Elicited in Infection

1992 • 218 citations

Non-Candida fungal infections after bone marrow transplantation: Risk factors and outcome

1994 • 216 citations

Brain Abscess Following Marrow Transplantation: Experience at the Fred Hutchinson Cancer Research Center, 1984-1992

1994 • 211 citations

Elevated cerebrospinal fluid pressures in patients with cryptococcal meningitis and acquired immunodeficiency syndrome

1991 • 205 citations

Fluconazole Combined with Flucytosine for Treatment of Cryptococcal Meningitis in Patients with AIDS

1994 • 203 citations

Prevention of Relapse of Histoplasmosis with Itraconazole in Patients with the Acquired Immunodeficiency Syndrome

1993 • 202 citations

Coccidioidomycosis during Human Immunodeficiency Virus Infection

1990 • 191 citations

Progress in the Diagnosis and Management of Aspergillosis in Bone Marrow Transplantation: 13 Years' Experience

1993 • 190 citations

The Emerging Role of Fusarium Infections in Patients with Cancer

1988 • 189 citations

Risk Factors for Fungal Infection in Patients with Malignant Hematologic Disorders: Implications for Empirical Therapy and Prophylaxis

1994 • 184 citations

Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity

1991 • 182 citations

Interaction of Azoles with Rifampin, Phenytoin, and Carbamazepine: In Vitro and Clinical Observations

1992 • 181 citations

LIPOSOMAL AMPHOTERICIN B PREVENTS INVASIVE FUNGAL INFECTIONS IN LIVER TRANSPLANT RECIPIENTS

1995 • 178 citations

The Effect of Ketoconazole on Amphotericin B in a Model of Disseminated Aspergillosis

1985 • 175 citations

Nosocomial Acquisition of Candida albicans: An Epidemiologic Study

1993 • 175 citations

Prophylactic Intravenous Amphotericin B in Neutropenic Autologous Bone Marrow Transplant Recipients

1992 • 171 citations

Diagnosis and Successful Treatment of Fusariosis in the Compromised Host

1988 • 165 citations

Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B

1994 • 140 citations

Clinical use of liposomal and lipid-complexed amphotericin B

1994 • 139 citations

Mechanisms and clinical impact of antifungal drug resistance

1994 • 134 citations

Cytokine treatment of central nervous system infection: efficacy of interleukin-12 alone and synergy with conventional antifungal therapy in experimental cryptococcosis

1994 • 133 citations

Fluconazole resistance due to energy-dependent drug efflux in Candida glabrata

1995 • 131 citations

The Triazole Antifungal Agents: A Review of Itraconazole and Fluconazole

1990 • 129 citations

Azole Therapy for Trichosporonosis: Clinical Evaluation of Eight Patients, Experimental Therapy for Murine Infection, and Review

1992 • 128 citations

Role of Granulocyte-Macrophage Colony-Stimulating Factor as Adjuvant Therapy for Fungal Infection in Patients with Cancer

1993 • 122 citations

Combination therapy of murine invasive candidiasis with fluconazole and amphotericin B

1995 • 116 citations

Phase I Study of Amphotericin B Colloidal Dispersion for the Treatment of Invasive Fungal Infections after Marrow Transplant

1996 • 115 citations

Infectious Complications in Adults with Bone Marrow Transplantation and T-Cell Depletion of Donor Marrow

1986 • 112 citations

Long-Term Amphotericin B Therapy for Disseminated Histoplasmosis in Patients with the Acquired Immunodeficiency Syndrome (AIDS)

1989 • 104 citations

Disseminated Infection with Fusarium in Recipients of Bone Marrow Transplants

1991 • 99 citations

In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin

1992 • 94 citations

Multiple dose pharmacokinetics of an oral solution of itraconazole in autologous bone marrow transplant recipients

1994 • 93 citations

In vitro activity of itraconazole against fluconazole-susceptible and -resistant Candida albicans isolates from oral cavities of patients infected with human immunodeficiency virus

1994 • 90 citations

In vitro evaluation of combination of fluconazole and flucytosine against Cryptococcus neoformans var. neoformans

1995 • 84 citations

Combined therapy with fluconazole and flucytosine in murine cryptococcal meningitis

1991 • 80 citations

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

1995 • 80 citations

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis

1994 • 71 citations

Safety of liposomal amphotericin B (AmBisome) in 187 transplant recipients treated with cyclosporin.

1994 • 66 citations

Disseminated Fusarium solani infection

1995 • 61 citations

Sterol composition of Cryptococcus neoformans in the presence and absence of fluconazole

1994 • 60 citations

Coccidioidomycosis among Persons with AIDS in the United States

1995 • 58 citations

Tissue distribution and bioactivity of amphotericin B administered in liposomes to cancer patients

1991 • 58 citations

Prophylactic use of liposomal amphotericin B (AmBisome) against fungal infections: a randomized trial in bone marrow transplant recipients.

1993 • 57 citations

Chitin biosynthesis in Candida albicans grown in vitro and in vivo and its inhibition by nikkomycin Z

1992 • 56 citations

New Methods of Delivery of Amphotericin B

1993 • 54 citations

Plasma itraconazole concentrations in neutropenic patients after repeated high-dose treatment

1992 • 53 citations

In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373

1995 • 52 citations

Prevention of relapse of histoplasmosis with fluconazole in patients with the acquired immunodeficiency syndrome

1994 • 50 citations

In vitro antifungal and fungicidal spectra of a new pradimicin derivative, BMS-181184

1995 • 49 citations

Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo

1992 • 49 citations

Efficacy of D0870 compared with those of itraconazole and amphotericin B in two murine models of invasive aspergillosis

1995 • 46 citations

Protective effect of human granulocyte colony stimulating factor (hG‐CSF) on Candida, infections in normal and immunosuppressed mice

1991 • 44 citations

In vitro and in vivo antifungal activities of D0870, a new triazole agent

1993 • 41 citations

Antifungal Activity of Recombinant Human Macrophage Colony-Stimulating Factor in Models of Acute and Chronic Candidiasis in the Rat

1994 • 41 citations

In vitro and in vivo antifungal activities of BMY-28864, a water-soluble pradimicin derivative

1991 • 40 citations

Successful treatment of aTrichosporon beigelii septicemia in a granulocytopenic patient with amphotericin B and granulocyte colony-stimulating factor

1994 • 38 citations

Interactions of amphotericin B and SCH 39304 in the treatment of experimental murine candidiasis: lack of antagonism of a polyene-azole combination

1991 • 38 citations

Stimulation of granulopoiesis by high-dose recombinant human granulocyte colony-stimulating factor in children with aplastic anemia and very severe neutropenia

1994 • 38 citations

Bloodstream Infection due to Trichosporon beigelii in a Burn Patient: Case Report and Review of Therapy

1995 • 38 citations

Pulmonary toxicity during infusion of liposomal amphotericin B in two patients with acute leukemia

1995 • 35 citations

Treatment of murine cryptococcal meningitis with an SCH 39304-amphotericin B combination

1991 • 28 citations

SAPERCONAZOLE IN THE TREATMENT OF SYSTEMIC AND SUBCUTANEOUS MYCOSES

1992 • 26 citations

Saperconazole therapy of murine disseminated candidiasis: efficacy and interactions with amphotericin B

1994 • 26 citations

Fluconazole and Amphotericin B Antifungal Therapies Do Not Negate the Protective Effect of Endogenous Tumor Necrosis Factor in a Murine Model of Fatal Disseminated Candidiasis

1995 • 25 citations

Granulocyte Transfusion Therapy

1994 • 25 citations

Effectiveness of an Oral Triazole for Opportunistic Mold Infections in Patients with Cancer: Experience with SCH 39304

1993 • 23 citations

In vitro and in vivo activities of SCH 42427, the active enantiomer of the antifungal agent SCH 39304

1992 • 22 citations

Efficacy of SCH 39304 in treatment of experimental invasive aspergillosis

1991 • 22 citations

Lipid-based amphotericin B in the treatment of cryptococcosis

1994 • 21 citations

Activities of D0870, a novel triazole, against Candida lusitaniae and Trichosporon beigelii in experimental murine infections

1995 • 18 citations

In vitro activity of a new antifungal triazole, D0870, against Candida albicans isolates from oral cavities of patients infected with human immunodeficiency virus

1994 • 14 citations

Treatment of coccidioidomycosis with SCH 39304

1994 • 11 citations