BIOSYNTHESIS OF HALOGENATED METABOLITES BY BACTERIA

Chloroperoxidase

1966 • 533 citations

Chloroperoxidase

1966 • 484 citations

AUREOMYCIN: A PRODUCT OF THE CONTINUING SEARCH FOR NEW ANTIBIOTICS

1948 • 480 citations

Bacterial dehalogenases: biochemistry, genetics, and biotechnological applications

1994 • 401 citations

Chloromycetin, a New Antibiotic From a Soil Actinomycete

1947 • 380 citations

Global control in Pseudomonas fluorescens mediating antibiotic synthesis and suppression of black root rot of tobacco.

1992 • 372 citations

Studies in the biochemistry of micro-organisms

1939 • 370 citations

Peroxidases from phaeophyceae: A vanadium(V)-dependent peroxidase from Ascophyllum nodosum

1984 • 344 citations

Stoffwechselprodukte von Mikroorganismen

1971 • 318 citations

Chemistry of Thyroxine

1927 • 315 citations

Biohalogenation Principles, Basic Roles and Applications

1987 • 288 citations

The Natural Production of Chlorinated Compounds

1994 • 266 citations

Methyl Chloride Transferase: a Carbocation Route for Biosynthesis of Halometabolites

1990 • 263 citations

Production and biological activity of rebeccamycin, a novel antitumor agent.

1987 • 246 citations

Secondary metabolites of the fluorescent pseudomonads

1979 • 236 citations

Interesting aspects of marine natural products chemistry

1977 • 235 citations

Pyrrolnitrin, a New Antibiotic Substance, Produced byPseudomonas

1964 • 222 citations

Halomethane from halide ion—a highly efficient fungal conversion of environmental significance

1985 • 215 citations

GENETICS AND BIOCHEMISTRY OF DEHALOGENATING ENZYMES

1994 • 199 citations

Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya.

1986 • 161 citations

Biotransformation of Halogenated Compounds

1991 • 161 citations

Cloning of Genes Involved in the Synthesis of Pyrrolnitrin from Pseudomonas fluorescens and Role of Pyrrolnitrin Synthesis in Biological Control of Plant Disease

1994 • 150 citations

The role of the chlorine substituents in the antibiotic vancomycin: preparation and characterization of mono- and didechlorovancomycin

1985 • 147 citations

Vanadium(V) as an essential element for haloperoxidase activity in marine brown algae: purification and characterization of a vanadium(V)-containing bromoperoxidase from Laminaria saccharina

1986 • 146 citations

Naturally occurring halogenated organic compounds.

1973 • 141 citations

Purification and some properties of 2-halobenzoate 1,2-dioxygenase, a two-component enzyme system from Pseudomonas cepacia 2CBS

1992 • 128 citations

Calicheamicins, a novel family of antitumor antibiotics. 3. Isolation, purification and characterization of calicheamicins .BETA.1Br, .GAMMA.1Br, .ALPHA.2I, .ALPHA.3I, .BETA.1I, .GAMMA.1I and .DELTA.1I.

1989 • 126 citations

Structure of nucleocidin. III. revised structure

1969 • 122 citations

Purification and characterization of a tetrachloro-p-hydroquinone reductive dehalogenase from a Flavobacterium sp

1992 • 120 citations

The bromoperoxidase from the lichen Xanthoria parietina is a novel vanadium enzyme

1987 • 119 citations

Refined X-ray Structures of Haloalkane Dehalogenase at pH 6·2 and pH 8·2 and Implications for the Reaction Mechanism

1993 • 117 citations

The metal-ion-free oxidoreductase from Streptomyces aureofaciens has an α/β hydrolase fold

1994 • 116 citations

Purification and properties of ovoperoxidase, the enzyme responsible for hardening the fertilization membrane of the sea urchin egg.

1984 • 115 citations

Cloning and Nucleotide Sequence of the Gene Responsible for Chlorination of Tetracycline

1995 • 112 citations

Purification and characterization of a novel bacterial non-heme chloroperoxidase from Pseudomonas pyrrocinia.

1988 • 100 citations

Pyrrolnitrin and phenazine production by Pseudomonas cepacia, strain 5.5B, a biocontrol agent of Rhizoctonia solani

1995 • 99 citations

Contribution of the Global Regulator Gene gacA to Persistence and Dissemination of Pseudomonas fluorescens Biocontrol Strain CHA0 Introduced into Soil Microcosms

1994 • 94 citations

Purification and properties of bromoperoxidase from Penicillus capitatus.

1981 • 77 citations

The non-haem chloroperoxidase from Pseudomonas fluorescens and its relationship to pyrrolnitrin biosynthesis

1996 • 76 citations

Stoffwechselprodukte von Mikroorganismen 73. Mitteilung [1] Chlorothricin und Des‐chlorothoricin

1969 • 74 citations

Pyrrolnitrin from Myxococcus fulvus (Myxobacterales).

1982 • 65 citations

Molecular cloning and sequencing of a non-haem bromoperoxidase gene from Streptomyces aureofaciens ATCC 10762

1992 • 64 citations

Isolation of the Toxic Principle in Acacia georginae

1961 • 63 citations

Chloroperoxidase-encoding gene from Pseudomonas pyrrocinia: sequence, expression in heterologous hosts, and purification of the enzyme

1993 • 63 citations

Metabolism of Tryptophans by Pseudomonas aureofaciens

1968 • 63 citations

Chloroperoxidase from Streptomyces lividans: isolation and characterization of the enzyme and the corresponding gene

1994 • 60 citations

Pyrroindomycins, novel antibiotics produced by Streptomyces rugosporus sp. LL-42D005. I. Isolation and structure determination.

1994 • 58 citations

Biosynthesis of fluorinated secondary metabolites by Streptomyces cattleya

1995 • 57 citations

Primary Structure and Characterization of the Vanadium Chloroperoxidase from the Fungus Curvularia inaequails

1995 • 57 citations

A comparison of different (vanadium) bromoperoxidases; the bromoperoxidase from Corallina pilulifera is also a vanadium enzyme

1989 • 56 citations

STRUCTURE OF A NEW ANTIBIOTIC, PYOLUTEORIN

1958 • 56 citations

Halogenation and Oxidation Reactions with Haloperoxidases

1994 • 56 citations

Detection of a new chloroperoxidase in Pseudomonas pyrrocinia

1986 • 52 citations

Purification and Properties of a Nonheme Bromoperoxidase fromStreptomyces aureofaciens

1987 • 52 citations

Formation of Pyrrolnitrin and 3‐(2‐Amino‐3‐chlorophenyl)pyrrole from 7‐Chlorotryptophan

1980 • 50 citations

Production and composition of phenylpyrrole metabolites prodcued by Pseudomonas cepacia

1990 • 50 citations

Bromoperoxidases from Penicillus capitatus, Penicillus lamourouxii and Rhipocephalus phoenix

1980 • 50 citations

The biosynthesis of brominated pyrrolnitrin derivatives by Pseudomonas aureofaciens.

1983 • 48 citations

Cloning of a second non-haem bromoperoxidase gene from Streptomyces aureofaciens ATCC 10762: sequence analysis, expression in Streptomyces lividans and enzyme purification

1994 • 46 citations

Biosynthesis of Tetracyclines. I. The Halide Metabolism of Streptomyces aureofaciens Mutants. The Preparation and Characterization of Tetracycline, 7-Chloro³⁶ -tetracycline and 7-Bromotetracycline

1959 • 46 citations

A catalytic triad is required by the non-heme haloperoxidases to perform halogenation

1995 • 46 citations

Biological Chlorination

1963 • 46 citations

New chlorinated nitro-pyrrole antibiotics, Pyrrolomycin A and B SE-2080 A and B.

1981 • 46 citations

The occurrence and metabolism of carbon—halogen compounds

1968 • 45 citations

Purification and Molecular and Catalytic Properties of Bromoperoxidase from Streptomyces phaeochromogenes

1985 • 44 citations

Purification, characterization and comparison of two non-haem bromoperoxidases from Streptomyces aureofaciens ATCC 10762

1991 • 44 citations

AN INTRODUCTION TO THE ORIGIN AND BIOCHEMISTRY OF MICROBIAL HALOMETABOLITES

1961 • 42 citations

Primary Structure and Characterization of the Vanadium Chloroperoxidase from the Fungus Curvularia inaequails

1995 • 41 citations

The Preparation and Spectral Characterization of 2-Haloindoles, 3-Haloindoles, and 2,3-Dihaloindoles

1986 • 41 citations

Isolation and Characterization of Streptomyces venezuelae Mutants Blocked in Chloramphenicol Biosynthesis

1985 • 41 citations

New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins.

1987 • 40 citations

EFFECT OF HALOGENS ON THE CHLORAMPHENICOL FERMENTATION

1958 • 37 citations

New Amino Acids from Streptomyces^*

1967 • 36 citations

Transductional analysis of chloramphenicol biosynthesis genes in Streptomyces venezuelae

1987 • 35 citations

The Biosynthesis of Nitro Compounds: The Enzymatic Oxidation to Pyrrolnitrin of Its Amino‐Substituted Precursor

1994 • 34 citations

A Metal‐Ion‐ and Cofactor‐independent Enzymatic Redox Reaction: Halogenation by Bacterial Nonheme Haloperoxidases

1991 • 33 citations

Biosynthesis of the Tetracyclines. VII.¹ 4-Hydroxy-6-methylpretetramid, an Intermediate Accumulated by a Blocked Mutant of Streptomyces aureofaciens²

1965 • 33 citations

Biosynthesis of the Tetracyclines

1965 • 33 citations

Conversion of 2-chloromaleylacetate in Alcaligenes eutrophus JMP134

1993 • 32 citations

Purification and some characteristics of a non-haem bromoperoxidase from Streptomyces aureofaciens

1988 • 31 citations

Synthesis of fluoroacetate from fluoride, glycerol, and beta-hydroxypyruvate by Streptomyces cattleya

1995 • 31 citations

A chlorinated phenylpyrrole antibiotic fromActinoplanes

1978 • 31 citations

Cloning, sequencing and disruption of a bromoperoxidase-catalase gene in Streptomyces venezuelae: evidence that it is not required for chlorination in chloramphenicol biosynthesis

1996 • 31 citations

Determination of 4‐chloroindoleacetic acid methyl ester in Vicieae species by gas chromatography‐mass spectrometry

1981 • 31 citations

Isolation and structural identification of nine avilamycins.

1986 • 31 citations

Purification and Properties of 4-Halobenzoate-Coenzyme A Ligase fromPseudomonas sp.CBS3

1992 • 29 citations

Pyrrolomycins F1,F2a,F2b and F3,new metabolites produced by the addition of bromide to the fermentation.

1983 • 28 citations

Purification, Properties and Immunological Detection of a Bromoperoxidase-Catalase from Streptomyces venezuelae and from a Chloramphenicol-nonproducing Mutant

1989 • 26 citations

Studies on the Biosynthesis of Antibiotics

1986 • 24 citations

Purification and properties of a non-haem chloroperoxidase fromSerratia marcescens

1995 • 23 citations

Isolation of the Bromo Analogues of Pyrrolnitrin from Pseudomonas pyrrolnitrica

1969 • 22 citations

Enzymatic chlorination using bacterial nonheme haloperoxidases

1994 • 22 citations

4-chlorothreonine, a herbicidal antimetabolite produced by streptomyces sp. OH-5093.

1994 • 21 citations

[54] Dichloromethane dehalogenase from Hyphomicrobium DM2

1990 • 20 citations

2'-Chloropentostatin: Discovery, fermentation and biological activity.

1985 • 20 citations

Purification and Partial Characterization of Multiple Bromoperoxidases from Streptomyces griseus

1988 • 20 citations

Production of Antibacterial Compounds Analogous to Chloramphenicol by an-Paraffin-grown Bacterium

1972 • 20 citations

Fluorocitrate in plants and food stuffs

1972 • 20 citations

Biosynthesis of the Tetracyclines. VIII.¹ Characterization of 4-Hydroxy-6-methylpretetramid²

1965 • 20 citations

Bacterial haloperoxidases and their role in secondary metabolism

1990 • 19 citations

Biosynthese von pyrrolnitrin - nachweis von 4-(2′-amino-3′-chlorphenyl)pyrrol-2-carbonsäure

1978 • 19 citations

Pyrrolnitrin: A New Mode of Tryptophan Metabolism

1967 • 16 citations

Biosynthese von pyrrolnitrin nachweis von 3-chloranthranilsaüre und 7-chlorindolessigsaure im kulturmedium von pseudomonas aureofaciens

1978 • 16 citations

The Metabolism of Tryptophan and 7-Chlorotryptophan inPseudomonas pyrrociniaandPseudomonas aureofaciens

1983 • 15 citations

Chloropolysporins A, B and C, novel glycopeptide antibiotics from Faenia interjecta sp. nov. III. Structure elucidation of chloropolysporins.

1987 • 15 citations

Production of Antibacterial Compounds Analogous to Chloramphenicol by a n-Paraffin-grown Bacterium

1972 • 15 citations

Studies on the Biosynthesis of Antibiotics1

1978 • 14 citations

(R-(Z))-4-amino-3-chloro-2-pentenedioic acid, a new antibiotic. Fermentation, isolation and characterization.

1984 • 13 citations

CP-54,883 a novel chlorine-containing polyether antibiotic produced by a new species of Actinomadura: Taxonomy of the producing culture, fermentation, physico-chemical and biological properties of the antibiotic.

1987 • 12 citations

Chlorocardicin, a monocyclic .BETA.-lactam from a Streptomyces sp. II. Isolation, physico-chemical properties and structure determination.

1985 • 11 citations

Isolation of the Bromo Analogues of Pyrrolnitrin fromPseudomonas pyrrolnitrica

1969 • 10 citations

A new antibiotic indisocin and N-methylindisocin.

1987 • 8 citations

Conserved Organization of Genes for Biosynthesis of Chlortetracycline inStreptomycesStrains

1995 • 7 citations

Purification and properties of a non-haem chloroperoxidase from

1995 • 6 citations

Biosynthesis of corynecins by Corynebacterium hydrocarboclastus: on the origin of the N-acyl group.

1976 • 6 citations

Chloropolysporins A, B and C, novel glycopeptide antibiotics from Faenia interjecta sp. nov. V. Comparative studies of the biological properties.

1987 • 4 citations

Pyrrolnitrin: A New Mode of Tryptophan Metabolism

1967 • 3 citations

Biochemical studies on Streptomyces aureofaciens. II. Ionic influences on the formation of chlortetracycline.

1962 • 2 citations

Biochemistry and genetics of chloramphenicol production

1983 • 1 citations