A Putative G Protein-Coupled Receptor, RDC1, Is a Novel Coreceptor for Human and Simian Immunodeficiency Viruses

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

The Molecular Biology of Leukocyte Chemoattractant Receptors

1994 • 1,224 citations

Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques

1985 • 929 citations

Genome organization and transactivation of the human immunodeficiency virus type 2

1987 • 842 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA

1968 • 706 citations

Expression cloning of new receptors used by simian and human immunodeficiency viruses

1997 • 692 citations

Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry

1999 • 688 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype

1997 • 609 citations

STRL33, A Novel Chemokine Receptor–like Protein, Functions as a Fusion Cofactor for Both Macrophage-tropic and T Cell Line–tropic HIV-1

1997 • 378 citations

Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry

1996 • 365 citations

Sequence of simian immunodeficiency virus from African green monkey, a new member of the HIV/SIV group

1988 • 336 citations

Restricted expression of human T-Cell leukemia-lymphoma virus (HTLV) in Transformed human umbilical cord blood lymphocytes

1983 • 332 citations

Identification of a Chemokine Receptor Encoded by Human Cytomegalovirus as a Cofactor for HIV-1 Entry

1997 • 309 citations

Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry

1997 • 307 citations

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection

1997 • 295 citations

CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

1997 • 264 citations

Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus

1991 • 257 citations

Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation

1990 • 253 citations

Characterization of HIV-1 neutralization escape mutants

1989 • 220 citations

Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1

1997 • 218 citations

Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor

1997 • 207 citations

The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1

1998 • 200 citations

Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells

1990 • 197 citations

A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5

1998 • 192 citations

Isolation and characterization of simian immunodeficiency virus from mandrills in Africa and its relationship to other human and simian immunodeficiency viruses

1988 • 163 citations

Host range mutant of human immunodeficiency virus type 1: modification of cell tropism by a single point mutation at the neutralization epitope in the env gene

1991 • 154 citations

Cloning of Human Genes Encoding Novel G Protein-Coupled Receptors

1994 • 151 citations

Cloning and expression of the human vasoactive intestinal peptide receptor.

1991 • 149 citations

Establishment and characterization of 10 cell lines derived from patients with adult T-cell leukemia.

1983 • 143 citations

Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion

1997 • 122 citations

Establishment of a New System for Determination of Coreceptor Usages of HIV Based on the Human Glioma NP-2 Cell Line

1999 • 117 citations

Human Immunodeficiency Virus and the Brain

1996 • 110 citations

Identification of the Chemokine Receptor TER1/CCR8 Expressed in Brain-Derived Cells and T Cells as a New Coreceptor for HIV-1 Infection

1998 • 89 citations

Primary SIVsm Isolates Use the CCR5 Coreceptor from Sooty Mangabeys Naturally Infected in West Africa: A Comparison of Coreceptor Usage of Primary SIVsm, HIV-2, and SIVmac

1998 • 85 citations

Use of a novel human immunodeficiency virus type 1 reporter virus expressing human placental alkaline phosphatase to detect an alternative viral receptor

1995 • 81 citations

Usage of the coreceptors CCR-5, CCR-3, and CXCR-4 by primary and cell line-adapted human immunodeficiency virus type 2

1997 • 76 citations

Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein

1997 • 71 citations

CD4-independent infection by human immunodeficiency virus type 2 strain ROD/B: the role of the N-terminal domain of CXCR-4 in fusion and entry

1997 • 50 citations

Isolation and characterization of human immunodeficiency virus type 1 variants infectious to brain-derived cells: detection of common point mutations in the V3 region of the env gene of the variants

1994 • 34 citations

A Novel Putative G Protein-Coupled Receptor Highly Expressed in Lung and Testis

1993 • 33 citations

The fine structure of human cerebral perivascular pericytes and juxtavascular phagocytes: their possible role in hydrocephalic edema resolution.

1990 • 28 citations

Isolation of human immunodeficiency virus from a Japanese hemophilia B patient with AIDS.

1987 • 27 citations

Characterization of the RDC1 gene which encodes the canine omolog of a proposed human VIP receptor Expression does not correlate with an increase in VIP binding sites

1992 • 25 citations

Clinical isolates of HIV-1 contain few pre-existing proteinase inhibitor resistance-conferring mutations

1995 • 18 citations

Detection of tryptase TL₂ and CD26 antigen in brain‐derived cells non‐permissive to T ‐cell line‐tropic human immunodeficiency virus type 1

1995 • 15 citations

Inhibition of Plating of Human T Cell Leukemia Virus Type I and Syncytium-Inducing Types of Human Immunodeficiency Virus Type 1 by Polycations

1997 • 13 citations