Serum Iodothyronines in the Human Fetus and the Newborn: Evidence for an Important Role of Placenta in Fetal Thyroid Hormone Homeostasis¹

Maternal and Fetal Thyroid Function

1994 • 687 citations

The role of thyroid hormones in prenatal and neonatal neurological development--current perspectives

1993 • 661 citations

Ontogenesis of Hypothalamic-Pituitary-Thyroid Function and Metabolism in Man, Sheep, and Rat

1977 • 384 citations

Maturation of the Secretion of Thyroid Hormone and Thyroid-Stimulating Hormone in the Fetus

1991 • 379 citations

Thyroid Hormone Metabolism

1994 • 268 citations

A Radioimmunoassay for Measurement of 3,3′, 5′-Triiodothyronine (Reverse T3)

1974 • 248 citations

Acute release of thyrotropin in the newborn

1969 • 234 citations

Detection of thyroid hormones in human embryonic cavities during the first trimester of pregnancy.

1993 • 232 citations

Type 2 iodothyronine deiodinase is highly expressed in human thyroid.

1996 • 200 citations

Human Placenta Is an Active Site of Thyroxine and 3,3',5-Triiodothyronine Tyrosyl Ring Deiodination*

1981 • 142 citations

Type II and type III deiodinase activity in human placenta as a function of gestational age.

1996 • 140 citations

Serum Triiodothyronine and Thyroxine in the Neonate and the Acute Increases in These Hormones Following Delivery

1973 • 128 citations

Fetal and Maternal Thyroid Hormones

1987 • 109 citations

Maternal to fetal thyroxine transmission in the human term placenta is limited by inner ring deiodination.

1996 • 97 citations

A radioimmunoassay for measurement of 3,5,3'-triiodothyronine sulfate: studies in thyroidal and nonthyroidal diseases, pregnancy, and neonatal life.

1992 • 92 citations

Sulfation Preceding Deiodination of Iodothyronines in Rat Hepatocytes

1983 • 88 citations

Alterations in Tissue Thyroxine-5′-Monodeiodinating Activity in Perinatal Period*

1978 • 85 citations

Thyroxine administration to infants of less than 30 weeks' gestational age does not increase plasma triiodothyronine concentrations

1993 • 79 citations

Decreased Outer Ring Monodeiodination of Thyroxine and Reverse Triiodothyronine in the Fetal and Neonatal Rat*

1978 • 79 citations

Umbilical Cord Cutting Triggers Hypertriiodothyroninemia and Nonshivering Thermogenesis in the Newborn Lamb

1976 • 64 citations

Thyroxine Inner Ring Monodeiodinating Activity in Fetal Tissues of the Rat

1988 • 60 citations

The development of a radioimmunoassay for reverse triiodothyronine sulfate in human serum and amniotic fluid.

1993 • 34 citations

Metabolism of sulfoconjugated thyroid hormone derivatives in developing sheep

1994 • 34 citations

Increased Plasma 3,5,3'-Triiodothyronine Sulfate in Rats with Inhibited Type I Iodothyronine Deiodinase Activity, as Measured by Radioimmunoassay*

1989 • 31 citations

Study of serum 3,5,3′-triiodothyronine sulfate concentration in patients with systemic non-thyroidal illness

1996 • 29 citations

A study of metabolism of deaminated and sulfoconjugated iodothyronines by rat placental iodothyronine 5-monodeiodinase.

1992 • 28 citations

A radioimmunoassay for measurement of thyroxine sulfate.

1993 • 28 citations

A study of the serum 3,5,3'-triiodothyronine sulfate concentration in normal and hypothyroid fetuses at various gestational stages.

1993 • 26 citations

Development of the hypothalamic-pituitary-thyroid axis in humans

1996 • 25 citations

3,5,3'-Triiodothyronine (T3) sulfate: a major metabolite in T3 metabolism in man.

1994 • 22 citations

Evaluation of L-thyroxine replacement therapy in children with congenital hypothyroidism

1991 • 22 citations

Serum thyroid hormones and tissue 5'-monodeiodinase activity in acutely thyroidectomized newborn lambs

1986 • 20 citations

A radioimmunoassay of rat type I iodothyronine 5'-monodeiodinase.

1992 • 19 citations

Phenylalanine kinetics in human adipose tissue.

1996 • 18 citations

Evidence that the human placental 5-monodeiodinase is a phospholipid-requiring enzyme.

1992 • 10 citations

The mechanism of low serum T3 in the fetus: hepatic T4-5'-monodeiodinase versus tissue sulfhydryl content--a clarification.

1986 • 6 citations