High Field¹H-NMR Analysis of the 1:1 Intercalation Complex of the Antitumor Agent Mitoxantrone and the DNA Duplex [d(CpGpCpG)]₂

Complex formation between ethidium bromide and nucleic acids

1965 • 1,485 citations

An NMR technique for tracing out the carbon skeleton of an organic molecule

1981 • 451 citations

Doxorubicin - Anticancer Antibiotics

1981 • 402 citations

CARDIAC TOXICITY OF DAUNORUBICIN

1969 • 345 citations

Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones

1979 • 279 citations

Oximate ion promoted unblocking of oligonucleotide phosphotriester intermediates

1978 • 197 citations

Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids

1981 • 149 citations

Activity of a novel anthracenedione, 1,4-dihydroxy-5,8-bis(((2-[(2-hydroxyethyl)amino]ethyl)amino])-9,10-anthracenedione dihydrochloride, against experimental tumors in mice.

1979 • 148 citations

Nucleic acid geometry and dynamics

1980 • 131 citations

Phase I clinical investigation of 1,4-dihydroxy-5,8-bis (( (2-[(2-hydroxyethyl)amino]ethyl) amino))-9,10-anthracenedione dihydrochloride (NSC 301739), a new anthracenedione.

1980 • 122 citations

Action of dihydroxyanthraquinone on cell cycle progression and survival of a variety of cultured mammalian cells.

1980 • 112 citations

Phase I clinical trial of mitoxantrone: A new anthracenedione anticancer drug

1980 • 60 citations

DNA-Binding Specificity and RNA Polymerase Inhibitory Activity of Bis(aminoalkyl)anthraquinones and Bis(methylthio)vinylquinolinium Iodides

1982 • 52 citations

Synthesis complete¹H assignments and conformations of the self-complementary hexadeoxyribonucleotide [d(CpGpApTpCpG)]₂and its fragments by high field NMR

1984 • 40 citations

Damage to the intrinsic cardiac neurones by rubidomycin (daunorubicin).

1969 • 36 citations

Activity of a novel anthracenyl bishydrazone, 9,10-anthracenedicarboxyaldehyde Bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] dihydrochloride, against experimental tumors in mice.

1982 • 33 citations

Molecular pharmacology of the anthracycline drug 9,10-anthracenedicarboxaldehyde bis[(4,5-dihydro-1 H-imidazol-2-yl)hydrazone] dihydrochloride (Cl 216,942).

1982 • 29 citations

Adriamycin-induced compaction of isolated chromatin

1982 • 22 citations