Continuous, on-line DNA sequencing using oligodeoxynucleotide primers with multiple fluorophores.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Fluorescence detection in automated DNA sequence analysis

1986 • 1,694 citations

Fluorescent Antibody Methods

1969 • 1,549 citations

A System for Rapid DNA Sequencing with Fluorescent Chain-Terminating Dideoxynucleotides

1987 • 852 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

Preparation of oligodeoxynucleotide-alkaline phosphatase conjugates and their use hybridization probes

1986 • 357 citations

The synthesis of oligonucleotides containing an aliphatic amino group at the 5′ terminus: synthesis of fluorescent DNA primers for use in DNA sequence analysis

1985 • 334 citations

Automated DNA sequencing: ultrasensitive detection of fluorescent bands during electrophoresis

1987 • 328 citations

Improvements of DNA sequencing gels

1981 • 269 citations

A non-radioactive automated method for DNA sequence determination

1986 • 243 citations

A Turning Point in Cancer Research: Sequencing the Human Genome

1986 • 230 citations

The plasmid cloning vector pBR325 contains a 482 base-pair-long inverted duplication

1981 • 213 citations

DNA sequencing with direct blotting electrophoresis.

1984 • 78 citations

System for DNA sequencing with resolution of up to 600 base pairs

1984 • 69 citations

Automated high-speed DNA sequencing

1987 • 64 citations

Current approaches to DNA sequencing

1987 • 10 citations