Activation of a vmp pseudogene in Borrella hermsii: an alternate mechanism of antigenic variation during relapsing fever

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

Isolation and cultivation of Lyme disease spirochetes.

1984 • 1,554 citations

Hybridization of nucleic acids immobilized on solid supports

1984 • 1,357 citations

On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletions

1982 • 690 citations

X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I

1978 • 419 citations

Linear Plasmids of the Bacterium Borrelia burgdorferi Have Covalently Closed Ends

1987 • 379 citations

Antigenic variation of Borrelia hermsii.

1982 • 322 citations

Molecular analysis of linear plasmid‐encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi

1989 • 317 citations

Enhanced protein thermostability from designed mutations that interact with α-helix dipoles

1988 • 290 citations

Specific-primer-directed DNA sequencing

1986 • 264 citations

Homology requirements for recombination in Escherichia coli.

1985 • 255 citations

Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii

1985 • 246 citations

POLYMERASE CHAIN REACTION STRATEGY

1992 • 225 citations

Variable major proteins of Borrellia hermsii.

1982 • 223 citations

Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesions

1992 • 219 citations

The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid

1993 • 208 citations

DNA transformation leads to pilin antigenic variation in Neisseria gonorrhoeae

1988 • 188 citations

Antigenic variation is associated with DNA rearrangements in a relapsing fever borrelia

1985 • 174 citations

ANTIGENIC VARIATION OF A RELAPSING FEVER BORRELIA SPECIES

1990 • 174 citations

Reassortment of pilin genes in Neisseria gonorrhoeae occurs by two distinct mechanisms

1989 • 167 citations

Improved hybridization assays employing tailed oligonucleotide probes: A direct comparison with 5′-end-labeled oligonucleotide probes and nick-translated plasmid probes

1985 • 161 citations

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments

1989 • 159 citations

Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization.

1992 • 155 citations

Linear plasmids of Borrelia burgdorferi have a telomeric structure and sequence similar to those of a eukaryotic virus

1991 • 153 citations

Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi

1992 • 138 citations

Linear- and circular-plasmid copy numbers in Borrelia burgdorferi

1992 • 135 citations

Genetic mechanisms of bacterial antigenic variation.

1988 • 123 citations

Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit

1986 • 116 citations

Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii.

1990 • 115 citations

The relapsing fever agent Borrelia hermsii has multiple copies of its chromosome and linear plasmids.

1992 • 113 citations

Variable antigen genes of the relapsing fever agent Borrelia hermsii are activated by promoter addition

1991 • 107 citations

A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae.

1991 • 106 citations

Variable major proteins of Borrelia hermsii. Epitope mapping and partial sequence analysis of CNBr peptides.

1985 • 89 citations

Silent pilin genes of Neisseria gonorrhoeae MS11 and the occurrence of related hypervariant sequences among other gonococcal isolates

1992 • 82 citations

DEVELOPMENTALLY REGULATED GENE REARRANGEMENTS IN PROKARYOTES

1992 • 82 citations

Subtelomeric expression regions of Borrelia hermsii linear plasmids are highly polymorphic

1992 • 80 citations

The variable antigens Vmp7 and Vmp21 of the relapsing fever bacterium Borrelia hermsii are structurally analogous to the VSG proteins of the African trypanosome

1990 • 76 citations

Antigenic variation in African trypanosomes

1992 • 63 citations

Experimental Infection of the Mouse Brain by a Relapsing Fever Borrelia Species: A Molecular Analysis

1993 • 50 citations

Isolation and characterization of Escherichia coli mutants with altered rates of deletion formation.

1991 • 44 citations

Detection of Plasmodium Falciparum in Blood Using DNA Hybridization

1985 • 43 citations

Cloning of 18S and 25S rDNAs from the pathogenic fungus Cryptococcus neoformans

1989 • 42 citations

The role of direct oligonucleotide repeats in gonococcal pilin gene variation

1990 • 41 citations

A Proposed Mechanism for Promoter-Associated DNA Rearrangement Events at a Variant Surface Glycoprotein Gene Expression Site

1992 • 39 citations

Intragenic recombination and a chimeric outer membrane protein in the relapsing fever agent Borrelia hermsii

1993 • 35 citations

A proposed mechanism for promoter-associated DNA rearrangement events at a variant surface glycoprotein gene expression site.

1992 • 21 citations

THE EFFECT OF NONHOMOLOGOUS DNA SEQUENCES ON INTERPLASMIDIC RECOMBINATION

1984 • 7 citations