Characterization of a neurologic disease induced by a polytropic murine retrovirus: evidence for differential targeting of ecotropic and polytropic viruses in the brain

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

1993 • 1,436 citations

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

1993 • 1,009 citations

Secretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1

1990 • 628 citations

Cytokine expression in the brain during the acquired immunodeficiency syndrome

1992 • 572 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

Clinical‐neuropathologic correlation in HIV‐associated dementia

1993 • 325 citations

A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice2

1973 • 200 citations

The Impact of Microglia-Derived Cytokines upon Gliosis in the CNS

1994 • 195 citations

The neurobiology of human immunodeficiency virus infections

1988 • 157 citations

Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-Recombinant viruses in mouse cells

1982 • 151 citations

Use of a focal immunofluorescence assay on live cells for quantitation of retroviruses: distinction of host range classes in virus mixtures and biological cloning of dual-tropic murine leukemia viruses

1985 • 133 citations

Production of monoclonal antibodies reactive with a denatured form of the friend murine leukemia virus gp70 envelope protein: Use in a focal infectivity assay, immunohistochemical studies, electron microscopy and western blotting

1991 • 121 citations

Hemolytic anemia and erythroleukemia, two distinct pathogenic effects of Friend MuLV: Mapping of the effects to different regions of the viral genome

1986 • 121 citations

Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus

1990 • 102 citations

Physical mapping of the paralysis-inducing determinant of a wild mouse ecotropic neurotropic retrovirus

1984 • 90 citations

A Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB

1990 • 86 citations

Different murine cell lines manifest unique patterns of interference to superinfection by murine leukemia viruses

1985 • 86 citations

Pathogenesis of the slow disease of the central nervous system associated with WM 1504 E virus. I. Relationship of strain susceptibility and replication to disease.

1977 • 80 citations

Murine retrovirus-induced spongiform encephalopathy: Productive infection of microglia and cerebellar neurons in accelerated CNS disease

1991 • 76 citations

Isolation of paralysis-inducing murine leukemia viruses from Friend virus passaged in rats

1984 • 69 citations

Spongiform polioencephalomyelopathy caused by a murine retrovirus. I. Pathogenesis of infection in newborn mice.

1980 • 64 citations

Moloney Murine Leukemia Virus Temperature-Sensitive Mutants: A Model for Retrovirus-Induced Neurologic Disorders

1990 • 63 citations

Retrovirus-induced spongiform myeloencephalopathy in mice: regional distribution of infected target cells and neuronal loss occurring in the absence of viral expression in neurons.

1991 • 54 citations

Viral determinants that control the neuropathogenicity of PVC-211 murine leukemia virus in vivo determine brain capillary endothelial cell tropism of the virus in vitro

1993 • 53 citations

Noninflammatory spongiform polioencephalomyelopathy caused by a neurotropic temperature-sensitive mutant of Moloney murine leukemia virus TB.

1986 • 52 citations

Cellular tropism and localization in the rodent nervous system of a neuropathogenic variant of Friend murine leukemia virus.

1992 • 52 citations

Murine retroviral neurovirulence correlates with an enhanced ability ofvirus to infect selectively, replicate in, and activate resident microglial cells.

1991 • 49 citations

Identification of the infected target cell type in spongiform myeloencephalopathy induced by the neurotropic Cas-Br-E murine leukemia virus

1993 • 47 citations

Kinetic analysis of spongiform neurodegenerative disease induced by a highly virulent murine retrovirus.

1994 • 47 citations

Characterization of a progressive neurodegenerative disease induced by a temperature-sensitive Moloney murine leukemia virus infection

1986 • 45 citations

Identification of a sequence in the unique 5' open reading frame of the gene encoding glycosylated Gag which influences the incubation period of neurodegenerative disease induced by a murine retrovirus

1994 • 45 citations

Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia

1995 • 44 citations

Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus

1990 • 38 citations

Wild Mouse Retrovirus: Pathogenesis

1990 • 30 citations

Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system

1993 • 24 citations

Prevention of retrovirus-induced neurological disease by infection with a nonneuropathogenic retrovirus

1995 • 11 citations

Ocular infection with a murine neurovirulent retrovirus does not cause retinal degeneration.

1992 • 3 citations