Oligomeric Structure of the Human EphB2 Receptor SAM Domain

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

MOLMOL: A program for display and analysis of macromolecular structures

1996 • 7,169 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

1994 • 1,211 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.

1990 • 1,013 citations

Crystal structure of cyclin-dependent kinase 2

1993 • 946 citations

Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 • 851 citations

A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia

1997 • 810 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.

1995 • 738 citations

A Novel Putative Tyrosine Kinase Receptor Encoded by the eph Gene

1987 • 430 citations

Switching Signals On or Off by Receptor Dimerization

1998 • 428 citations

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

1998 • 423 citations

Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement

1997 • 347 citations

Improved Structure Refinement Through Maximum Likelihood

1996 • 341 citations

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

1995 • 329 citations

SAM as a protein interaction domain involved in developmental regulation

1997 • 299 citations

The novel activation of ABL by fusion to an ets-related gene, TEL.

1995 • 289 citations

The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-dependent signaling pathways

1996 • 285 citations

SnB: crystal structure determination via shake-and-bake

1994 • 280 citations

Protein–protein interaction at crystal contacts

1995 • 261 citations

Phase combination and cross validation in iterated density-modification calculations

1996 • 250 citations

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFRbeta oncoprotein

1997 • 220 citations

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

1998 • 202 citations

Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps

1995 • 187 citations

Molecular Cloning of a Novel Diacylglycerol Kinase Isozyme with a Pleckstrin Homology Domain and a C-terminal Tail Similar to Those of the EPH Family of Protein-tyrosine Kinases

1996 • 163 citations

CNK, a RAF-Binding Multidomain Protein Required for RAS Signaling

1998 • 162 citations

Ligand Activation of ELK Receptor Tyrosine Kinase Promotes Its Association with Grb10 and Grb2 in Vascular Endothelial Cells

1996 • 145 citations

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site

1998 • 139 citations

A Domain Shared by the Polycomb Group Proteins Scm and ph Mediates Heterotypic and Homotypic Interactions

1997 • 139 citations

Function of the Eph-related kinase rtk1 in patterning of the zebrafish forebrain

1996 • 113 citations

The Drosophila Polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein

1996 • 107 citations

[31] Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

1997 • 102 citations

Multiple Regulatory Domains on the Byr2 Protein Kinase

1997 • 82 citations

The SAM domain of polyhomeotic, RAE28, and Scm mediates specific interactions through conserved residues

1998 • 67 citations

Identification of new partner chromosomes involved in fusions with theETV6 (TEL) gene in hematologic malignancies

1998 • 50 citations