Mechanism of protein folding

Are there pathways for protein folding?

1968 • 1,496 citations

Carp Muscle Calcium-binding Protein

1973 • 1,359 citations

Structural patterns in globular proteins

1976 • 1,286 citations

The structure and action of proteins

1969 • 741 citations

Structure of crystalline α-chymotrypsin

1972 • 675 citations

The formation and stabilization of protein structure

1972 • 372 citations

Folding of Polypeptide Chains in Proteins: A Proposed Mechanism for Folding

1971 • 309 citations

Molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-Å resolution

1975 • 266 citations

A High Resolution Structure of an Inhibitor Complex of the Extracellular Nuclease of Staphylococcus aureus

1971 • 264 citations

Acquisition of Three-Dimensional Structure of Proteins

1973 • 248 citations

A model of myoglobin self-organization

1975 • 207 citations

Experimental Free Energy and Enthalpy of Formation of the α Helix¹

1966 • 146 citations

The amino acid sequence of γ-crystallin (fraction II) from calf lens

1972 • 119 citations

The Amino-Acid Sequence of Trout-Testis Histone H1

1977 • 105 citations

On the rate‐determining step for helix propagation in the helix–coil transition of polypeptides in solution

1975 • 76 citations

A theory of protein molecule self-organization

1976 • 75 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. II. Characterization of the Host Polymers and Application of the Host-Guest Technique to Random Poly(hydroxypropylglutamine-co-hydroxybutylglutamine)

1971 • 74 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. IV. Alanine Parameters from Random Poly(hydroxypropylglutamine-co-L-alanine)

1972 • 74 citations

Structural Rules for Globular Proteins

1977 • 63 citations

Potentiometric titration of poly‐<scp>L</scp>‐lysine: the coil‐to‐β transition

1971 • 60 citations

Helix‐coil stability constants for the naturally occurring amino acids in water. XII. Asparagine parameters from random poly(hydroxybutylglutamine‐co‐<scp>L</scp>‐asparagine)

1977 • 57 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. III. Glycine Parameters from Random Poly(hydroxybutylglutamine-co-glycine)

1971 • 56 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. VI. Leucine Parameters from Random Poly(hydroxypropylglutamine-co-L-leucine) and Poly(hydroxybutylglutamine-co-L-leucine)

1972 • 54 citations

Helix–coil transition of poly‐<scp>L</scp>‐arginine: A comparison with other basic polypeptides

1969 • 54 citations

Helix-Coil Stability Constants for the Naturally Occuring Amino Acids in Water. X. Tyrosine Parameters from Random Poly(hydroxypropylglutamine-co-L-tyrosine)

1976 • 52 citations

Kinetics and thermodynamics of the α helix ⇄ β transconformation of poly(L-lysine) and L-leucine copolymers. Compensation phenomenon

1973 • 52 citations

Theory of protein molecule self‐organization. II. A comparison of calculated thermodynamic parameters of local secondary structures with experiments

1977 • 48 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. IX. Glutamic Acid Parameters from Random Poly(hydroxybutylglutamine-co-L-glutamic acid)

1975 • 47 citations

Helix-Coil Stability for the Naturally Occurring Amino Acids in Water. VIII. Valine Parameters from Random Poly(hydroxypropylglutamine-co-L-valine) and Poly(hydroxybutylglutamine-co-L-valine)

1973 • 46 citations

Conformational studies on copolymers of hydroxypropyl-L-glutamine and L-leucine. Circular dichroism studies

1972 • 45 citations

Conformational studies on copolymers ofL-leusine andL-leucine: Circular dichroism and potentiometric titration studies

1972 • 44 citations

Thermodynamic parameters of helix-coil transitions in polypeptide chains

1972 • 42 citations

Theory of protein molecule self‐organization. I. Thermodynamic parameters of local secondary structures in the unfolded protein chain

1977 • 38 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. 15. Arginine Parameters from Random Poly(hydroxybutylglutamine-co-L-arginine)

1977 • 34 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. V. Serine Parameters from Random Poly(hydroxybutylglutamine-co-L-serine)

1972 • 33 citations

Secondary Structure of Poly-<scp>l</scp>-arginine and Its Derivatives

1969 • 33 citations

Stability of the helical conformation of random <scp>L</scp>‐alanine–<scp>L</scp>‐lysine copolymers in aqueous solution

1970 • 32 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino in Water. VII Phenylalanine Parameters from Random Poly(hydroxypropylglutamine-co-L-L-phenylalanine)

1973 • 29 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. 16. Aspartic Acid Parameters from Random Poly(hydroxybutylglutamine-co-L-aspartic acid)

1977 • 28 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. 11. Lysine Parameters from Random Poly(hydroxybutylglutamine-co-L-lysine)

1976 • 24 citations

Helix‐coil stability constants for the naturally occuring amino acids in water. XIV. Methionine parameters from random poly(hydroxypropylglutamine,<scp>L</scp>‐Methionine)

1977 • 22 citations

Potentiometric and Microcalorimetric Determination of the Termodynamic Parameters of the Order-Disorder Transition of Poly(L-histidine) in Aqueous Solution

1972 • 20 citations

Thermodynamic Parameters for the Intramolecular Disordered-to-β Transition of Poly(Ltyrosine) in Aqueous Solution

1976 • 17 citations

The random coil → β transition of copolymers of <scp>L</scp>‐lysine and <scp>L</scp>‐valine: Potentiometric titration and circular dichroism studies

1975 • 17 citations

Kinetic study of the rapid reaction between amylose and iodine

1969 • 11 citations

The random coil → β transition of copolymers of <scp>L</scp>‐lysine and <scp>L</scp>‐isoleucine: Potentiometric titration and circular dichroism studies

1977 • 10 citations

Potentiometric Titration and the Stability of Helical Conformation of L-Alanine-L-glutamic Acid Copolymers in Aqueous Solution

1967 • 9 citations

Correction - On the Ring-Opening Polymerization of Methylenecyclobutane

1972 • 2 citations