Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia.

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

2013 • 2,504 citations

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

1986 • 2,118 citations

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1990 • 1,756 citations

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1991 • 1,108 citations

Electrolyte solutions

1970 • 785 citations

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

1990 • 706 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

1990 • 576 citations

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

1991 • 550 citations

Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.

1984 • 532 citations

Cystic fibrosis: a disease in electrolyte transport

1990 • 510 citations

Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

1991 • 508 citations

Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia.

1991 • 373 citations

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin.

1981 • 369 citations

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

1990 • 340 citations

Structural Analysis of a Human Intestinal Epithelial Cell Line

1987 • 193 citations

Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule

1990 • 136 citations

Epithelial properties of human colonic carcinoma cell line Caco-2: effect of secretagogues

1985 • 133 citations

Histamine and inositol phosphate accumulation in endothelium: cAMP and a G protein

1989 • 83 citations

Vesicle Recycling and Cell-Specific Function in Kidney Epithelial Cells

1989 • 33 citations

Back to the chloride channel

1991 • 17 citations

Staphylococcus aureus alpha-toxin permeabilizes the basolateral membrane of a Cl(-)-secreting epithelium

1992 • 15 citations

Vesicle Recycling And Cell-Specific Function In Kidney Epithelial Cells

1989 • 2 citations