Identification of More than One Mutation in the Hepatitis B Virus Polymerase Gene Arising during Prolonged Lamivudine Treatment
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Abstract
References (14)
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements.
1989 • 1,195 citations
A Preliminary Trial of Lamivudine for Chronic Hepatitis B Infection
1995 • 820 citations
Rapid Changes in Human Immunodeficiency Virus Type 1 RNA Load and Appearance of Drug-Resistant Virus Populations in Persons Treated with Lamivudine (3TC)
1995 • 524 citations
Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine
1996 • 470 citations
Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation
1997 • 456 citations
Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudinein vivo
1996 • 454 citations
Lamivudine prophylaxis against reinfection in liver transplantation for hepatitis B cirrhosis
1996 • 398 citations
High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase
1993 • 320 citations
Lamivudine resistance inimmunocompetent chronic hepatitis B
1997 • 276 citations
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine
1993 • 234 citations
Quantitation of human immunodeficiency virus type 1 RNA in cell free seminal plasma: comparison of NASBA™ with Amplicor™ reverse transcription-PCR amplification and correlation with quantitative culture
1996 • 107 citations
Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (−)-2′,3′-dideoxy-3′-thiacytidine
1995 • 84 citations
Generation of duck hepatitis B virus polymerase mutants through site-directed mutagenesis which demonstrate resistance to lamivudine [(--)-beta-L-2', 3'-dideoxy-3'-thiacytidine] in vitro
1996 • 68 citations
New nucleoside analogues for chronic hepatitis B.
1995 • 55 citations