Compositional features of eukaryotic genomes for checking predicted genes

The comparative method in evolutionary biology

1992 • 5,093 citations

A Draft Sequence of the Rice Genome ( Oryza sativa L. ssp. indica )

2002 • 4,221 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Ab initio Gene Finding in Drosophila Genomic DNA

2000 • 1,095 citations

Molecular archaeology of the Escherichia coli genome

1998 • 937 citations

RefSeq and LocusLink: NCBI gene-centered resources

2001 • 899 citations

The Mosaic Genome of Warm-Blooded Vertebrates

1985 • 887 citations

Directional mutation pressure and neutral molecular evolution.

1988 • 872 citations

Analytic approaches to twin data using structural equation models

2002 • 739 citations

Isochores and the evolutionary genomics of vertebrates

2000 • 555 citations

The genome sequence and structure of rice chromosome 1

2002 • 555 citations

Compositional constraints and genome evolution

1986 • 451 citations

THE HUMAN GENOME: Organization and Evolutionary History

1995 • 375 citations

Integration of cytogenetic landmarks into the draft sequence of the human genome

2001 • 320 citations

The distribution of genes in the human genome

1991 • 255 citations

Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores

1995 • 246 citations

An analysis of eukaryotic genomes by density gradient centrifugation

1976 • 242 citations

An analysis of the bovine genome by Cs2SO4—Ag+ density gradient centrifugation

1973 • 210 citations

Interpolated Markov Models for Eukaryotic Gene Finding

1999 • 202 citations

The gene distribution of the human genome

1996 • 199 citations

Correlations between the compositional properties of human genes, codon usage, and amino acid composition of proteins

1991 • 173 citations

Directional mutation pressure, selective constraints, and genetic equilibria

1992 • 166 citations

The Major Components of the Mouse and Human Genomes

1981 • 158 citations

RiceGAAS: an automated annotation system and database for rice genome sequence

2002 • 135 citations

Localization of the gene-richest and the gene-poorest isochores in the interphase nuclei of mammals and birds

2002 • 132 citations

Misunderstandings about isochores. Part 1

2001 • 116 citations

CpG doublets, CpG islands and Alu repeats in long human DNA sequences from different isochore families

1998 • 113 citations

Segmental Duplications: What's Missing, Misassigned, and Misassembled—and Should We Care?: Figure 1.

2001 • 102 citations

Human Coding and Noncoding DNA: Compositional Correlations

1996 • 102 citations

The correlation of protein hydropathy with the base composition of coding sequences

1999 • 94 citations

Bivariate allometry: Interval estimation of the slopes of the ordinary and standardized normal major axes and structural relationship

1990 • 94 citations

The compositional evolution of vertebrate genomes

2000 • 91 citations

Identification of the gene-richest bands in human prometaphase chromosomes.

1999 • 84 citations

The gene-richest bands of human chromosomes replicate at the onset of the S-phase

1998 • 78 citations

A universal compositional correlation among codon positions

1992 • 75 citations

The compositional properties of human genes

1991 • 72 citations

Compositional mapping of chicken chromosomes and identification of the gene-richest regions.

2001 • 70 citations

The isochore patterns of mammalian genomes and their phylogenetic implications

1993 • 70 citations

A compact view of isochores in the draft human genome sequence

2002 • 69 citations

Gene density in the Giemsa bands of human chromosomes.

2000 • 59 citations

On the Nature of Theories: A Neurocomputational Perspective

1997 • 51 citations

The compositional patterns of the avian genomes and their evolutionary implications

1993 • 47 citations

Genes, isochores and bands in human chromosomes 21 and 22.

2001 • 38 citations

Compositional heterogeneity within and among isochores in mammalian genomes

2001 • 37 citations

The distribution of genes in the Drosophila genome

2000 • 34 citations

Single-copy sequence homology among the GC-richest isochores of the genomes from warm-blooded vertebrates

1994 • 29 citations

Compositional Correlations in the Chicken Genome

1999 • 24 citations

Diversity and Phylogenetic Implications of CsCl Profiles from Rodent DNAs

2000 • 21 citations

Isochore conservation between MHC regions on human chromosome 6 and mouse chromosome 17

2002 • 18 citations

Incorrectly predicted genes in rice?

2004 • 14 citations