Two functionally distinct 4-aminopyridine-sensitive outward K+ currents in rat atrial myocytes.

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

Multiple potassium–channel components are produced by alternative splicing at the Shaker locus in Drosophila

1988 • 495 citations

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

1990 • 461 citations

Transient outward current prominent in canine ventricular epicardium but not endocardium.

1988 • 442 citations

Heteromultimeric channels formed by rat brain potassium-channel proteins

1990 • 409 citations

Comparison of potassium currents in rabbit atrial and ventricular cells.

1988 • 382 citations

Multiple products of the drosophila Shaker gene may contribute to potassium channel diversity

1988 • 324 citations

Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain

1990 • 317 citations

A rapid technique for the isolation and purification of adult cardiac muscle cells having respiratory control and a tolerance to calcium

1976 • 305 citations

Characterization of two distinct depolarization-activated K+ currents in isolated adult rat ventricular myocytes.

1991 • 295 citations

Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle.

1990 • 276 citations

4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers.

1979 • 257 citations

Heteropolymeric potassium channels expressed in xenopus oocytes from cloned subunits

1990 • 247 citations

Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart.

1991 • 244 citations

Two types of transient outward currents in adult human atrial cells

1987 • 231 citations

Ionic basis of the different action potential configurations of single guinea‐pig atrial and ventricular myocytes.

1985 • 223 citations

Existence of two transient outward currents in sheep cardiac Purkinje fibers

1982 • 223 citations

Expression of a Cloned Rat Brain Potassium Channel in Xenopus Oocytes

1989 • 202 citations

Calcium‐sensitive and insensitive transient outward current in rabbit ventricular myocytes.

1989 • 176 citations

Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes

1988 • 174 citations

Potassium channels expressed from rat brain cDNA have delayed rectifier properties

1988 • 173 citations

A transient outward current in isolated cells from the crista terminalis of rabbit heart.

1985 • 166 citations

Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: Role of the transient outward current

1989 • 154 citations

Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library

1990 • 149 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel family.

1990 • 143 citations

Gating mechanism of a cloned potassium channel expressed in frog oocytes and mammalian cells

1990 • 132 citations

THE POTASSIUM CURRENT UNDERLYING DELAYED RECTIFICATION IN CAT VENTRICULAR MUSCLE

1978 • 132 citations

Oxygen requirements, morphology, cell coat and membrane permeability of calcium-tolerant myocytes from hearts of adult rats

1981 • 107 citations

Passive properties and membrane currents of canine ventricular myocytes.

1987 • 107 citations

Transient outward current carried by potassium and sodium in quiescent atrioventricular node cells of rabbits.

1985 • 96 citations

Age-related changes of action potential plateau shape in isolated human atrial fibers

1985 • 92 citations

Adrenergic modulation of the transient outward current in isolated canine Purkinje cells.

1988 • 87 citations

A novel type of depolarization-activated K+ current in isolated adult rat atrial myocytes

1991 • 85 citations

Properties of the transient outward current in rabbit atrial cells.

1988 • 83 citations

Cloning and expression of a rat cardiac delayed rectifier potassium channel.

1991 • 71 citations

A study of the effect of the rate of stimulation on the transient outward current in sheep cardiac Purkinje fibres.

1981 • 64 citations

Transient outward current and rate dependence of action potential duration in rabbit cardiac ventricular muscle

1983 • 63 citations

Calcium- and voltage-activated plateau currents of cardiac Purkinje fibers.

1987 • 61 citations

Strontium, nifedipine and 4‐aminopyridine modify the time course of the action potential in cells from rat ventricular muscle

1984 • 56 citations

State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells.

1990 • 52 citations

Potassium currents in cardiac cells

1987 • 39 citations

Effect of rate‐dependent changes in the transient outward current on the action potential in sheep Purkinje fibres.

1981 • 39 citations

Three types of single K channels contribute to the transient outward current in myocardial mouse cells.

1988 • 14 citations