Impact of postmenopausal hormone therapy on cardiovascular events and cancer: pooled data from clinical trials

A Simple Sequentially Rejective Multiple Test Procedure

1979 • 20,726 citations

BMPD statistical software manual

1988 • 2,605 citations

ASSESSMENT OF FRACTURE RISK AND ITS APPLICATION TO SCREENING FOR POSTMENOPAUSAL OSTEOPOROSIS

1994 • 2,556 citations

Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women

1992 • 2,379 citations

Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women

1995 • 2,281 citations

Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients

1994 • 2,186 citations

The Use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women

1995 • 1,532 citations

Single-Drug Therapy for Hypertension in Men -- A Comparison of Six Antihypertensive Agents with Placebo

1993 • 1,210 citations

Treatment of Postmenopausal Osteoporosis with Transdermal Estrogen

1992 • 824 citations

Estrogen Replacement Therapy II: A Prospective Study in the Relationship to Carcinoma and Cardiovascular and Metabolic Problems

1979 • 451 citations

The Minimum Effective Dose of Estrogen for Prevention of Postmenopausal Bone Loss

1985 • 399 citations

Late Assessment of Thrombolytic Efficacy (LATE) study with alteplase 6-24 hours after onset of acute myocardial infarction

1993 • 361 citations

Estrogen Replacement Therapy

1983 • 271 citations

The Comparative Effect on Bone Density, Endometrium, and Lipids of Continuous Hormones as Replacement Therapy (CHART Study)

1996 • 263 citations

Calcium Supplementation with and without Hormone Replacement Therapy To Prevent Postmenopausal Bone Loss

1994 • 249 citations

A communitywide perspective of sex differences and temporal trends in the incidence and survival rates after acute myocardial infarction and out-of-hospital deaths caused by coronary heart disease.

1993 • 243 citations

Impact of clinical trials on clinical practice: example of thrombolysis for acute myocardial infarction

1993 • 218 citations

Do women with acute myocardial infarction receive the same treatment as men?

1994 • 216 citations

The effect of percutaneous estradiol and natural progesterone on postmenopausal bone loss

1987 • 214 citations

Use of Menopausal Estrogens and Medroxyprogesterone in the United States, 1982-1992

1995 • 199 citations

Reversal of postmenopausal vertebral bone loss by oestrogen and progestogen: a double blind placebo controlled study

1988 • 167 citations

Short- and long-term clinical outcome after Q wave and non-Q wave myocardial infarction in a large patient population.

1989 • 147 citations

In-hospital prognosis of patients with first nontransmural and transmural infarctions.

1980 • 142 citations

Are women using postmenopausal estrogens? A community survey.

1990 • 138 citations

“Transmural” versus “Subendocardial” myocardial infarction: An electrocardiographic myth

1983 • 133 citations

Estrogen Replacement Therapy and Fatal Ovarian Cancer

1995 • 126 citations

The long-term effect of oral and percutaneous estradiol on plasma renin substrate and blood pressure.

1987 • 123 citations

Coronary heart disease and estrogen replacement therapy can compliance bias explain the results of observational studies?

1994 • 114 citations

Estrogen/gestagen therapy changes soft tissue body composition in postmenopausal women

1989 • 112 citations

Effect of progestin therapy on cortical and trabecular bone: comparison with estrogen

1991 • 105 citations

Dose-response evaluation of cyclic estrogen/gestagen in postmenopausal women: Placebo-controlled trial of its gynecologic and metabolic actions

1982 • 104 citations

The Trial of Antihypertensive Interventions and Management (TAIM) Study: Final Results With Regard to Blood Pressure, Cardiovascular Risk, and Quality of Life

1992 • 100 citations

Non-Q wave myocardial infarction: Recent changes in occurrence and prognosis—a community-wide perspective

1987 • 94 citations

The history of coronary care units.

1987 • 90 citations

Evidence that hospital care for acute myocardial infarction has not contributed to the decline in coronary mortality between 1973-1974 and 1978-1979.

1982 • 89 citations

Decline in the rate of hospital mortality from acute myocardial infarction: Impact of changing management strategies

1996 • 84 citations

Is oestrogen therapy effective in the treatment of menopausal depression?

1981 • 83 citations

Trends in survival of hospitalized myocardial infarction patients between 1970 and 1985. The Minnesota Heart Survey.

1992 • 80 citations

Trends in coronary heart disease mortality : the influence of medical care

1988 • 75 citations

Effect of oral oestriol on vaginal flora and cytology and urogenital symptoms in the post-menopause

1990 • 71 citations

Declining hospital mortality in acute myocardial infarction

1994 • 71 citations

Effect of placebo on 24-h non-invasive ambulatory blood pressure

1991 • 70 citations

Two new combinations of estrogen and progestogen for prevention of postmenopausal bone loss: Long‐term effects on bone, calcium and lipid metabolism, climacteric symptoms and bleeding

1992 • 66 citations

Utilisation of hormone replacement therapy by women doctors

1995 • 65 citations

A two-year double-blind controlled study of the clinical effect of combined and sequential postmenopausal replacement therapy and steroid metabolism during treatment

1993 • 64 citations

British Heart Foundation surveys (1987 and 1989) of United Kingdom treatment policies for acute myocardial infarction.

1991 • 63 citations

BENEFITS OBTAINED BY THE INTRODUCTION OF A CORONARY‐CARE UNIT

1971 • 62 citations

Comparison of clinical features of non-Q wave and Q wave myocardial infarction

1986 • 54 citations

Secular trends in Q wave and non-Q wave acute myocardial infarction. The Minnesota Heart Survey.

1991 • 54 citations

Trends in the use of climacteric and postclimacteric hormones in Nordic countries

1995 • 53 citations

The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART study). A randomized controlled trial

1996 • 53 citations

Impact of hospital thrombolysis policy on out-of-hospital response to suspected myocardial infarction

1993 • 51 citations

Effect of estrone sulfate on postmenopausal bone loss

1991 • 51 citations

Management of myocardial infarction: implications for current policy derived from the Nottingham Heart Attack Register.

1992 • 49 citations

Colorectal cancer and oestrogen replacement therapy: A meta‐analysis of epidemiological studies

1995 • 49 citations

Physicians' views on hormone therapy around and after menopause

1993 • 47 citations

Estrogen and progestin therapy to prevent osteoporosis

1990 • 41 citations

Continuous combined and sequential estradiol and norethindrone acetate treatment of postmenopausal women: Effect on plasma lipoproteins in a two-year placebo-controlled trial

1994 • 40 citations

Low and High Renin Essential Hypertension: A Comparison of Clinical and Biochemical Characteristics

1981 • 40 citations

Q wave, S-T segment, and T wave myocardial infarction. Useful clinical distinction

1985 • 39 citations

95143045 Quality of life during sequential hormone replacement therapy—A placebo-controlled study

1995 • 35 citations

Age and cardiovascular response adaptation. Determinants of an antihypertensive treatment concept primarily based on beta-blockers and calcium entry blockers.

1983 • 32 citations

Long-term and withdrawal effects of two different oestrogen-progestogen combinations on lipid and lipoprotein profiles in post-menopausal women

1989 • 29 citations

Postmenopausal estrogens--current prescribing patterns of San Diego gynecologists.

1986 • 28 citations

Reduced in-hospital mortality from acute myocardial infarction with general adoption of thrombolytic treatment in the North West Thames health region 1979-1991.

1995 • 26 citations

Prevention of early postmenopausal bone loss: controlled 2-year study in 315 normal females

1971 • 22 citations

Recurrent myocardial infarction. 1. Natural History of fatal and non-fatal events

1985 • 22 citations

95101234 The influence of menopause and hormonal replacement therapy on body cell mass and body fat mass

1995 • 21 citations

HOW MUCH OF THE CARDIOPROTECTIVE EFFECT OF POSTMENOPAUSAL ESTROGENS IS REAL?

1995 • 20 citations

Changes in calcanean bone mineral occurring spontaneously and during hormone replacement therapy in early post-menopausal women

1992 • 10 citations

Myocardial Infarction in Patients over 75 1982–1990

1992 • 9 citations

The increased use of diagnostic procedures in patients with acute myocardial infarction. A community-wide perspective

1987 • 8 citations

OESTROGEN REPLACEMENT THERAPY FOR PREVENTION OF OSTEOPOROSIS AFTER OOPHORECTOMY

1974 • 6 citations

90329215 Are women using postmenopausal estrogens? A community survey

1991 • 5 citations

95132782 Estrogen replacement therapy and fatal ovarian cancer

1995 • 5 citations