Processing, Secretion, and Anti-HIV-1 Activity of IL-16 With or Without a Signal Peptide in CD4+ T Cells

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Making antibody fragments using phage display libraries

1991 • 1,195 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

Genetic and Pharmacological Suppression of Oncogenic Mutations in RAS Genes of Yeast and Humans

1989 • 535 citations

PDZ Proteins Organize Synaptic Signaling Pathways

1998 • 474 citations

PROTEIN GLYCOSYLATION IN YEAST

1987 • 437 citations

Protein glycosylation in yeast

1987 • 339 citations

Crystal structure of a PDZ domain

1996 • 315 citations

Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression.

1994 • 274 citations

Interleukin 16 and its function as a CD4 ligand

1996 • 261 citations

Modulation of lymphocyte migration by human lymphokines. I. Identification and characterization of chemoattractant activity for lymphocytes from mitogen-stimulated mononuclear cells.

1982 • 252 citations

Processing and Activation of Pro-Interleukin-16 by Caspase-3

1998 • 243 citations

Isolation and analysis of the C-terminal signal directing export of Escherichia coli hemolysin protein across both bacterial membranes.

1989 • 231 citations

Escherichia coli hemolysin is released extracellularly without cleavage of a signal peptide

1985 • 217 citations

CD4-mediated stimulation of human eosinophils: lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration.

1991 • 214 citations

Lymphokine activation of T4+ T lymphocytes and monocytes.

1987 • 195 citations

A novel family of variable region genes of the human immunoglobulin heavy chain

1987 • 187 citations

Modulation of lymphocyte migration by human lymphokines. II. Purification of a lymphotactic factor (LCF).

1982 • 165 citations

Secretion of IL-16 (lymphocyte chemoattractant factor) from serotonin-stimulated CD8+ T cells in vitro.

1996 • 150 citations

Molecular cloning, sequence, expression, and processing of the interleukin 16 precursor

1997 • 136 citations

Histamine-induced secretion of lymphocyte chemoattractant factor from CD8+ T cells is independent of transcription and translation. Evidence for constitutive protein synthesis and storage.

1995 • 132 citations

Human CD4+ cells transfected with IL-16 cDNA are resistant to HIV-1 infection: Inhibition of mRNA expression

1997 • 123 citations

IL-16 represses HIV-1 promoter activity.

1997 • 122 citations

Purification of a factor which provides a costimulatory signal for gamma interferon production

1993 • 118 citations

Lymphocyte chemoattractant factor induces CD4-dependent intracytoplasmic signaling in lymphocytes.

1991 • 112 citations

Modulation of lymphocyte migration by human lymphokines

1984 • 74 citations

Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site

1998 • 50 citations

Cells Transfected with a Non-Neutralizing Antibody Gene Are Resistant to HIV Infection: Targeting the Endoplasmic Reticulum and Trans-Golgi Network

1998 • 40 citations

A novel family of variable region genes of the human immunoglobulin heavy chain

1990 • 34 citations

Molecular basis of genetic polymorphism in major histocompatibility complex-linked proteasome gene (Lmp-2).

1993 • 31 citations