Infection with the carcinogenic human liver fluke, Opisthorchis viverrini

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Liver Fluke Induces Cholangiocarcinoma

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Food-Borne Trematodiases

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Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos

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Opisthorchis viverrini: an underestimated parasite in world health

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Cross‐sectional study of Opisthorchis viverrini infection and cholangiocarcinoma in communities within a high‐risk area in northeast thailand

1994 • 186 citations

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

2009 • 180 citations

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1999 • 179 citations

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2005 • 179 citations

Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase

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1995 • 173 citations

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1999 • 170 citations

Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6

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Unlocking the Transcriptomes of Two Carcinogenic Parasites, Clonorchis sinensis and Opisthorchis viverrini

2010 • 150 citations

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2000 • 145 citations

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Transmission of a Malignant New Growth by Means of a Cell-Free Filtrate

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The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini

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1994 • 137 citations

Proepithelin Promotes Migration and Invasion of 5637 Bladder Cancer Cells through the Activation of ERK1/2 and the Formation of a Paxillin/FAK/ERK Complex

2006 • 137 citations

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Helminths in human carcinogenesis

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PC cell-derived growth factor (PCDGF/GP88, progranulin) stimulates migration, invasiveness and VEGF expression in breast cancer cells

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Granulin–Epithelin Precursor Overexpression Promotes Growth and Invasion of Hepatocellular Carcinoma

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Opisthorchis viverrini infection and cholangiocarcinoma

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1989 • 104 citations

Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma

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opisthorchis viverrini infestation and endogenous nitrosamines as risk factors for cholangiocarcinoma in thailand

1991 • 100 citations

Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini

2007 • 99 citations

Increased nitrosamine and nitrate biosynthesis mediated by nitric oxide synthase induced in hamsters infected with liver fluke (Opisthorchis viverrini)

1994 • 89 citations

Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini

2004 • 80 citations

Relationship between parasite‐specific antibody responses and intensity of Opisthorchis viverrini infection in hamsters

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The Role of Helminth Infections in Carcinogenesis

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Opisthorchis viverrini: life cycle, intermediate hosts, transmission to man and geographical distribution in Thailand.

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Infection with liver flukes (Opisthorchis viverrini, Opisthorchis felineus and Clonorchis sinensis).

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The role of nitrogen oxides as effector molecules of parasite killing

1990 • 72 citations

Expression of progranulin and the epithelin/granulin precursor acrogranin correlates with neoplastic state in renal epithelium.

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Schistosoma haematobium total antigen induces increased proliferation, migration and invasion, and decreases apoptosis of normal epithelial cells

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Relationships between the synthesis of N-nitrosodimethylamine and immune responses to chronic infection with the carcinogenic parasite, Opisthorchis viverrini, in men

1998 • 64 citations

SHORT COMMUNICATION: Promotion of cholangiocarcinogenesis in the hamster liver by bile duct ligation after dimethylnitrosamine initiation

1993 • 64 citations

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1999 • 39 citations

Gene expression profiling defined pathways correlated with fibroblast cell proliferation induced by Opisthorchis viverrini excretory/secretory product

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Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

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Pathogenesis of Helicobacter pylori Infection

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Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)

2000 • 27 citations

Progress on the transcriptomics of carcinogenic liver flukes of humans—Unique biological and biotechnological prospects

2010 • 27 citations

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Cholangiocarcinoma in experimental hamsters with long-standing Opisthorchis viverrini infection.

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Cancer: the role of extracellular disease

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The Granulin-Epithelin Precursor Is a Steroid-Regulated Growth Factor in Endometrical Cancer

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1999 • 18 citations

Proteomic identification of peroxiredoxin 6 for host defence againstOpisthorchis viverriniinfection

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Cancer survival in Khon Kaen, Thailand.

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Hyperplasia of gastric mucosa in donor rats orally infected with Taenia taeniaeformis eggs and in recipient rats surgically implanted with the larvae in the abdominal cavity

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Human peripheral blood mononuclear cells stimulated by Schistosoma mansoni antigens: association between protein tyrosine kinases, mitogen-activated protein kinases and cytokine production

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Early lesions induced by DHPN in Syrian golden hamsters: influence of concomitant Opisthorchisinfestation, dehydroepiandrosterone or butylated hydroxyanisole administration

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