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Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans

Data up to Jan 2025

Published1997
Citations117
References13

Total Citations Per Year

Abstract

References (13)

The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer

1992 • 321 citations

Pharmacokinetics of Citalopram in Relation to the Sparteine and the Mephenytoin Oxidation Polymorphisms

1993 • 214 citations

Racemization, enantiomerization, diastereomerization, and epimerization: Their meaning and pharmacological significance

1995 • 151 citations

Analysis of Enantiomers of Citalopram and Its Demethylated Metabolites in Plasma of Depressive Patients Using Chiral Reverse-Phase Liquid Chromatography

1995 • 126 citations

Identification of cytochrome P450 isoforms involved in citalopram N-demethylation by human liver microsomes.

1997 • 126 citations

SEROTONIN‐SELECTIVE ANTIDEPRESSANTS.

1985 • 83 citations

Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs.

1986 • 82 citations

Determination of the enantiomers of citalopram, its demethylated and propionic acid metabolites in human plasma by chiral HPLC

1995 • 72 citations

Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation

1996 • 67 citations

High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients

1984 • 67 citations

The Effect of Age and Concomitant Treatment with Other Psychoactive Drugs on Serum Concentrations of Citalopram Measured with a Nonenantioselective Method

1996 • 38 citations

Computation of Model-Independent Pharmacokinetic Parameters During Multiple Dosing

1984 • 20 citations

Molecular Asymmetry and Its Pharmacological Consequences

1991 • 12 citations

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Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in… (1997) – Chirality | Metascience Observatory Explorer