Application of a human tumor colony-forming assay to new drug screening.

Quantitation of Differential Sensitivity of Human-Tumor Stem Cells to Anticancer Drugs

1978 • 982 citations

Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy

1981 • 378 citations

A Critical Appraisal of the Human Tumor Stem-Cell Assay

1983 • 365 citations

Prospective clinical trial of a human tumor cloning system.

1983 • 340 citations

Multidrug-resistance phenotype in Chinese hamster ovary cells.

1983 • 194 citations

Growth of human tumour cell colonies from biopsies using two soft-agar techniques

1978 • 172 citations

Chemosensitivity testing of human solid tumors. A review of 1582 assays with 258 clinical correlations

1984 • 131 citations

Drug resistance in Chinese hamster lung and mouse tumor cells.

1983 • 105 citations

Preclinical drug development: rationale and methods.

1981 • 92 citations

Vinca alkaloid-resistant phenotype in cultured human leukemic lymphoblasts.

1983 • 91 citations

Inhibition of human ovarian cancer colony formation by adriamycin and its major metabolites.

1980 • 88 citations

Activity of mitoxantrone in a human tumor cloning system.

1981 • 87 citations

New drugs in ovarian cancer and malignant melanoma: in vitro phase II screening with the human tumor stem cell assay.

1981 • 78 citations

Evaluation of new-anthracycline analogs with the human tumor stem cell assay

1981 • 69 citations

The National Cancer Chemotherapy Program

1982 • 65 citations

Colony growth in soft agar of human melanoma, sarcoma, and lung carcinoma cells disaggregated by mechanical and enzymatic methods.

1980 • 58 citations

The National Cancer Institute antitumor drug discovery program, current and future perspectives: a commentary.

1983 • 51 citations

Colony growth and chemosensitivity in vitro of human melanoma biopsies. relationship to clinical parameters

1982 • 41 citations

Activity of 9–10 anthracenedicarboxaldehyde bis[(4,5-dihydro-1 H-imidazol-2-yl)hydrazone]dihydrochloride (CL216,942) in a human tumor cloning system

1981 • 39 citations

Evidence for multidrug-resistant cells in human tumor cell populations.

1983 • 39 citations

Cloning of human solid tumors in soft agar

1982 • 33 citations

In Vitro Chemosensitivity Assay Based on the Concept of Total Tumor Cell Kill

1984 • 31 citations

In vitro chemosensitivities of human tumor stem cells to the Phase II drug 4'-(9-acridinylamino)methanesulfon-m-anisidide and prospective in vivo correlations.

1982 • 25 citations

Potentials and drawbacks of the human tumor stem cell assay.

1984 • 23 citations

Soft agar colony formation assay for chemotherapy sensitivity testing of human solid tumors.

1982 • 19 citations

In vitro versus in vivo correlations of chemosensitivity of human medulloblastoma.

1984 • 11 citations