Aphidicolin inhibits DNA synthesis by DNA polymerase α and isolated nuclei by a similar mechanism

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-α

1978 • 904 citations

Errors in DNA replication as a basis of malignant changes.

1974 • 527 citations

EUKARYOTIC CHROMOSOME REPLICATION

1975 • 455 citations

Replication of Eukaryotic Chromosomes: A Close-up of the Replication Fork

1980 • 330 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1969 • 272 citations

Uracil DNA-glycosylase from HeLa cells: general properties, substrate specificity and effect of uracil analogs

1981 • 171 citations

Involvement of eucaryotic deoxyribonucleic acid polymerases .alpha. and .gamma. in the replication of cellular and viral deoxyribonucleic acid

1979 • 171 citations

The Mode of Inhibitory Action by Aphidicolin on Eukaryotic DNA Polymerase α

1979 • 146 citations

Effect of 2′, 3′-dideoxythymidine-5′-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase α is the only polymerase required for cellular DNA replication

1978 • 145 citations

HeLa Cell R-Deoxyribonucleic Acid Polymerases

1974 • 136 citations

Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes

1980 • 100 citations

Further characterization of a cell-free system for measuring replicative and repair DNA synthesis with cultured human fibroblasts and evidence for the involvement of DNA polymeraseain DNA repair

1979 • 96 citations

The effect of aphidicolin on adenovirus DNA synthesis

1979 • 84 citations

The effect of aphidicolin on DNA synthesis in isolated HeLa cell nuclei

1979 • 82 citations

DNA synthesis in isolated HeLa cell nuclei. Optimalization of the system and characterization of the product

1975 • 81 citations

Isolation and characterization of a UV-sensitive hypermutable aphidicolin-resistant Chinese hamster cell line

1982 • 72 citations

DNA polymerase alpha mutants from a Drosophila melanogaster cell line.

1980 • 56 citations

The mode of action of aphidicolin on DNA synthesis in isolated nuclei

1980 • 52 citations

DNA synthesis in isolated HeLa cell nuclei. Evidence for in vitro initiation of synthesis of small pieces of DNA and their subsequent ligation

1975 • 44 citations

Differential effect of aphidicolin on adenovirus DNA synthesis and cellular DNA synthesis

1980 • 39 citations

Increase in dATP pool in aphidicolin-resistant mutants of mouse FM3A cells

1979 • 38 citations

Studies on the inhibition of highly purified calf thymus 8S and 7.3S DNA polymeiase α by aphidicolin

1981 • 26 citations

Aphidicolin resistant mutant of which DNA polymerase α is induced by this drug

1979 • 23 citations

Inhibition of DNA synthesis in the adenovirus DNA replication complex by aphidicolin and 2′,3′-dideoxythymidine triphosphate

1980 • 22 citations

Effect of aphidicolin and 2′,3′-dideoxythymidine on mitochondrial DNA replication

1980 • 12 citations

Preservation by glycerol of DNA synthetic capacity of isolated HeLa S3 cell nuclei during long term storage at low temperature

1978 • 9 citations