Transduction Diversity in Olfaction

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

1988 • 1,777 citations

Carbon Monoxide: a Putative Neural Messenger

1993 • 1,519 citations

A cyclic nucleotide-gated conductance in olfactory receptor cilia

1987 • 1,134 citations

A zonal organization of odorant receptor gene expression in the olfactory epithelium

1993 • 1,050 citations

Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium

1993 • 870 citations

G _olf : an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction

1989 • 863 citations

Neurobiology of Taste and Smell

1988 • 790 citations

Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons

1990 • 650 citations

Ion Channel Reconstitution

1986 • 605 citations

Odorant-sensitive adenylate cyclase may mediate olfactory reception

1985 • 583 citations

Rapid kinetics of second messenger formation in olfactory transduction

1990 • 438 citations

The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.

1986 • 433 citations

The family of genes encoding odorant receptors in the channel catfish

1993 • 402 citations

Analysis of the electrical activity of the olfactory epithelium.

1955 • 391 citations

A new subunit of the cyclic nucleotide-gated cation channel in retinal rods

1993 • 370 citations

Coding of olfactory information: Topography of odorant receptor expression in the catfish olfactory epithelium

1993 • 353 citations

Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells

1993 • 330 citations

Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells

1993 • 315 citations

Rapid activation of alternative second messenger pathways in olfactory cilia from rats by different odorants.

1990 • 292 citations

Calcium-activated chloride conductance in frog olfactory cilia

1991 • 288 citations

Odor Stimuli Trigger Influx of Calcium Into Olfactory Neurons of the Channel Catfish

1990 • 287 citations

Cloning and expression of odorant receptors

1993 • 277 citations

Cell biology of olfaction

1992 • 276 citations

Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons

1992 • 264 citations

Primary structure of cAMP‐gated channel from bovine olfactory epithelium

1990 • 260 citations

Receptor cell responses to odorants: Similarities and differences among odorants

1984 • 250 citations

Olfactory sensitivity to bile acids in salmonid fishes

1980 • 246 citations

Implications of the NO/cGMP system for olfaction

1993 • 245 citations

Plasma membrane inositol 1,4,5-Trisphosphate-Activated channels mediate signal transduction in lobster olfactory receptor neurons

1992 • 235 citations

The relation between stimulus and response in olfactory receptor cells of the tiger salamander.

1993 • 232 citations

Functional properties of vertebrate olfactory receptor neurons

1986 • 229 citations

Origin of the chloride current in olfactory transduction

1993 • 227 citations

The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium

1991 • 224 citations

Signaling pathways in odorant detection

1992 • 218 citations

Contributions of topography and parallel processing to odor coding in the vertebrate olfactory pathway

1991 • 210 citations

Olfaction and taste in the channel catfish: An electrophysiological study of the responses to amino acids and derivatives

1978 • 200 citations

Chemical transmission in the nose of the frog.

1965 • 198 citations

Responses of olfactory bulb neurones to odour stimulation of small nasal areas in the salamander

1974 • 195 citations

Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage.

1992 • 193 citations

Odor-Induced Membrane Currents in Vertebrate-Olfactory Receptor Neurons

1989 • 191 citations

Ca2+-dependent adaptive properties in the solitary olfactory receptor cell of the newt

1990 • 187 citations

Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system

1991 • 185 citations

Expression of odorant receptors in spatially restricted subsets of chemosensory neurones

1992 • 181 citations

Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.

1991 • 179 citations

Mechanotransduction

1992 • 179 citations

Activation by odorants of cation‐selective conductance in the olfactory receptor cell isolated from the newt.

1989 • 165 citations

Intracellular Ca2+ regulates the sensitivity of cyclic nucleotide-gated channels in olfactory receptor neurons

1992 • 163 citations

Single odor-sensitive channels in olfactory receptor neurons are also gated by cyclic nucleotides

1991 • 162 citations

Spatial pattern of receptor expression in the olfactory epithelium.

1992 • 160 citations

Electrical Responses of the Olfactory Epithelium of Atlantic Salmon (Salmo salar)

1971 • 152 citations

The spatial distributions of odorant sensitivity and odorant‐induced currents in salamander olfactory receptor cells.

1991 • 150 citations

A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination.

1993 • 146 citations

Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf.

1990 • 145 citations

Molecular messengers of olfaction

1992 • 144 citations

The response induced by intracellular cyclic AMP in isolated olfactory receptor cells of the newt.

1990 • 141 citations

Chemosensory Transduction Mechanisms in Taste

1992 • 141 citations

Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurones.

1990 • 138 citations

Olfactory receptors

1993 • 135 citations

Topographic coding of olfactory quality: odorant-specific patterns of epithelial responsivity in the salamander

1982 • 133 citations

Responses of olfactory receptor cells to step pulses of odour at different concentrations in the salamander.

1978 • 133 citations

Patch-clamp studies of isolated mouse olfactory receptor neurons.

1987 • 131 citations

Odorant‐ and Guanine Nucleotide‐Stimulated Phosphoinositide Turnover in Olfactory Cilia^a

1987 • 128 citations

Inhibition of the olfactory cyclic nucleotide gated ion channel by intracellular calcium

1991 • 121 citations

Synaptic circuitry of the retina and olfactory bulb

1993 • 116 citations

Contribution of the ciliary cyclic nucleotide‐gated conductance to olfactory transduction in the salamander.

1993 • 114 citations

Gated currents in isolated olfactory receptor neurons of the larval tiger salamander.

1987 • 113 citations

Olfactory responses to amino acids in rainbow trout, Salmo gairdneri

1973 • 111 citations

Dual activation of a sex pheromone-dependent ion channel from insect olfactory dendrites by protein kinase C activators and cyclic GMP.

1991 • 108 citations

Divalent cations block the cyclic nucleotide-gated channel of olfactory receptor neurons

1993 • 106 citations

A patch-clamp analysis of membrane currents in salamander olfactory receptor cells

1986 • 105 citations

Histamine directly gates a chloride channel in lobster olfactory receptor neurons.

1989 • 104 citations

Cyclic nucleotides mediate an odor-evoked potassium conductance in lobster olfactory receptor cells

1992 • 103 citations

Quantitative stimulation of frog olfactory receptors.

1969 • 102 citations

Amino acids as olfactory stimuli in fresh-water catfish, Ictalurus catus (Linn.)

1971 • 100 citations

Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides.

1991 • 99 citations

Adaptive properties of olfactory receptors analysed with odour pulses of varying durations.

1978 • 98 citations

Towards a common strategy for transducing olfactory information

1994 • 96 citations

ODOR DISCRIMINATION BY FROG OLFACTORY RECEPTORS

1974 • 90 citations

Inhibition of lobster olfactory receptor cells by an odor-activated potassium conductance

1991 • 90 citations

Synaptic transmission and modulation in the olfactory bulb

1993 • 90 citations

Nitric oxide mediated formation of cyclic GMP in the olfactory system

1992 • 87 citations

Liposomes as a model for olfactory cells: changes in membrane potential in response to various odorants

1987 • 85 citations

A Rapid Quantitative Bioassay for Evaluating the Effects of Ligands Upon Receptors That Modulate cAMP Levels in a Melanophore Cell Line

1992 • 81 citations

Chemosensory responses in isolated olfactory receptor neurons from Necturus maculosus.

1992 • 81 citations

IP3-and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish

1992 • 81 citations

Molecular neurobiology of olfaction.

1993 • 79 citations

Whole-cell currents in olfactory receptor cells of Xenopus laevis

1989 • 79 citations

Olfactory adenylate cyclase of the rat Stimulation by odorants and inhibition by Ca2+

1986 • 78 citations

Behavioral Responses to Chemical Stimulation of the Olfactory Organ in the Squid Loligo Opalescens

1992 • 78 citations

Cell biology of olfaction

1993 • 78 citations

Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish

1993 • 77 citations

Odorant response of isolated olfactory receptor cells is blocked by amiloride

1988 • 75 citations

High density cAMP-gated channels at the ciliary membrane in the olfactory receptor cell

1991 • 74 citations

Odor psychophysics in vertebrates

1985 • 67 citations

Electrical Responses to Chemical Stimulation of Squid Olfactory Receptor Cells

1992 • 67 citations

SELECTED AND STANDARDIZED VALUES OF SUPRATHRESHOLD ODOR INTENSITIES FOR 110 SUBSTANCES

1975 • 64 citations

Voltage-dependent and odorant-regulated currents in isolated olfactory receptor neurons of the channel catfish.

1992 • 64 citations

The recording of odorant-induced mucosal activity patterns with a voltage-sensitive dye

1992 • 63 citations

Cyclic nucleotide‐activated channels in the frog olfactory receptor plasma membrane

1990 • 61 citations

Hyperpolarizing receptor potentials in lobster olfactory receptor cells: implications for transduction and mixture suppression

1989 • 60 citations

Action potentials and chemosensitive conductances in the dendrites of olfactory neurons suggest new features for odor transduction.

1994 • 56 citations

Single-Channel Fluctuations in Bimolecular Lipid Membranes Induced by Rat Olfactory Epithelial Homogenates

1983 • 55 citations

Spatial Distribution of Receptor‐Responses to Stimulation with Different Odours

1971 • 55 citations

Structure-activity relationships of amino acids in fish olfaction

1976 • 54 citations

Interaction of GTP-binding regulatory proteins with chemosensory receptors.

1987 • 53 citations

Degeneration and Regeneration of the Olfactory Epithelium

1971 • 51 citations

Voltage-Sensitive Dyes and Functional Activity in the Olfactory Pathway

1992 • 51 citations

Olfactory thresholds in unilaterally bulbectomized rats

1984 • 51 citations

Odor Theory and Odor Classification

1982 • 51 citations

Unitary Responses in Frog Olfactory Epithelium to Sterically Related Molecules at Low Concentrations

1974 • 51 citations

Electrophysiological responses from the peripheral olfactory system of the American eel,Anguilla rostrata

1982 • 50 citations

Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences

1992 • 49 citations

Activation by odorants of a multistate cation channel from olfactory cilia.

1988 • 48 citations

Neuroblastoma cell as model for olfactory cell: Mechanism of depolarization in response to various odorants

1984 • 48 citations

Evidence for non-receptor odor discrimination using neuroblastoma cells as a model for olfactory cells

1985 • 47 citations

Odour discrimination by frog olfactory receptors: a second study

1978 • 41 citations

Stimulation of olfactory receptors alters regulation of [Cai] in olfactory neurons of the catfish (Ictalurus punctatus)

1991 • 41 citations

Effects of nitric oxide upon olfactory receptor neurones in Xenopus laevis

1993 • 40 citations

Histamine-induced modulation of olfactory receptor neurones in two species of lobster, Panulirus argus and Homarus americanus

1989 • 39 citations

Cyclic nucleotide-gated channels of rat olfactory receptor cells: divalent cations control the sensitivity to cAMP.

1994 • 38 citations

Olfaction by melanophores: what does it mean?

1988 • 37 citations

Current recording from sensory cilia of olfactory receptor cells in situ. II. Role of mucosal Na+, K+, and Ca2+ ions.

1991 • 37 citations

Odour threshold determined by studies of the induced waves in the olfactory bulb of the char (Salmo alpinus L.)

1977 • 37 citations

Single unit recording from olfactory cilia

1990 • 37 citations

Whole cell recording from lobster olfactory receptor cells: responses to current and odor stimulation

1989 • 32 citations

Ionic currents and ion channels of lobster olfactory receptor neurons.

1989 • 31 citations

Modulation of Cl-, K+, and nonselective cation conductances by taurine in olfactory receptor neurons of the mudpuppy Necturus maculosus.

1993 • 31 citations

An Electrophysiological Characterization of Ciliated Olfactory Receptor Cells of the Coho Salmon Oncorhynchus Kisutch

1992 • 29 citations

Odor-induced metabolic activity in the olfactory bulb of rats trained to detect propionic acid vapor

1989 • 29 citations

Odor Sensitivity of Cultured Lobster Olfactory Receptor Neurons is Not Dependent on Process Formation

1993 • 28 citations

Differential Localization of G Proteins, G, and G<sub>o</sub>, in the Olfactory Epithelium and the Main Olfactory Bulb of the Rat

1992 • 27 citations

Immunohistochemical localization of guanine nucleotide-binding proteins in rat olfactory epithelium during development

1990 • 27 citations

Whole cell recording from lobster olfactory receptor cells: multiple ionic bases for the receptor potential

1990 • 24 citations

Simultaneous recording of [Ca2+]i increases in isolated olfactory receptor neurons retaining their original spatial relationship in intact tissue

1992 • 24 citations

Minimum Odorant Concentrations Detectable by the Dog and Their Implications for Olfactory Receptor Sensitivity

1977 • 24 citations

Sustained primary culture of lobster (Panulirus argus) olfactory receptor neurons

1991 • 23 citations

Membrane fluidity changes of liposomes in response to various odorants. Complexity of membrane composition and variety of adsorption sites for odorants

1990 • 23 citations

Expression of G-protein Subunits in Rat Olfactory Neuroepithelium: Candidates for Olfactory Signal Transduction

1988 • 23 citations

The cyclic nucleotide-activated conductance in olfactory cilia: Effects of cytoplasmic Mg2+ and Ca2+

1993 • 23 citations

ATP and GTP are essential for olfactory response

1987 • 22 citations

Sensitivity and transduction mechanisms of responses to general odorants in turtle vomeronasal system.

1991 • 22 citations

Intracellular injection of vital dyes into single cells in the salamander olfactory epithelium

1992 • 21 citations

Peripheral mechanisms of olfactory discrimination of complex mixtures by the spiny lobster: no cell types for mixtures but different contributions of the cells to the across neuron patterns

1990 • 19 citations

Physiology of chemoreceptor cells in the legs of the freshwater prawn, macrobrachium rosenbergii

1988 • 18 citations

Central processing of olfaction

1991 • 18 citations

Olfactory signalling in antennal receptor neurones of the locust (Locusta migratoria)

1993 • 18 citations

Cyclic nucleotide-activated channels in carp olfactory receptor cells

1993 • 18 citations

High resolution 2-deoxyglucose localization in olfactory epithelium

1981 • 18 citations

Cell suspensions from porcine olfactory mucosa. Changes in membrane potential and membrane fluidity in response to various odorants.

1987 • 14 citations

Early events in olfaction: diversity and spatial patterns of odorant receptors.

1993 • 12 citations

Similarity of ion dependence of odorant responses between lipid bilayer and olfactory system

1989 • 11 citations

Single cyclic nucleotide-activated ion channel activity in olfactory receptor cell soma membrane

1990 • 11 citations

Molecular mechanisms of reception and transduction in olfaction and taste.

1990 • 10 citations

Fifteenth Annual Meeting of the Association for Chemoreception Sciences (AChemS XV)

1993 • 9 citations

Differential ion dependence of frog olfactory responses to various odorants

1991 • 9 citations

Ligand and Ion Specificity of IP3-Gated Channels in Lobster Olfactory Receptor Cells

1994 • 4 citations

Olfaction

1992 • 4 citations