Diagnostic and therapeutic management of cancer of an unknown primary

SEER Cancer Statistics Review, 1975-2003

2006 • 11,387 citations

Cancer Incidence in Five Continents

1970 • 8,763 citations

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Cancer Incidence in Five Continents

1966 • 5,960 citations

An Immunohistochemical Study

1989 • 1,928 citations

Meta-Analysis: Surgical Treatment of Obesity

2005 • 1,579 citations

Cancer: Principles and Practice of Oncology

1997 • 1,408 citations

Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. Evidence of major therapeutic activity in the anaplastic variants of these neoplasms

1991 • 843 citations

The management of brain metastases

2003 • 646 citations

Peritioneal carcinomatosis in nongynecologic malignancy. A prospective study of prognostic factors

1989 • 597 citations

Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients.

1994 • 349 citations

Cervical lymph node metastases from unknown primary tumours

2000 • 327 citations

Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin.

1995 • 319 citations

Cytokeratins 20 and 7 as biomarkers

2002 • 282 citations

Incidence of Cancer in the Netherlands 1998

2002 • 262 citations

Breast MR Imaging in Patients with Axillary Node Metastases and Unknown Primary Malignancy

1999 • 231 citations

Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984–1992

2002 • 217 citations

MALIGNANT MELANOMA OF UNKNOWN PRIMARY ORIGIN.

1963 • 215 citations

Metastatic and histologic presentations in unknown primary cancer.

1977 • 207 citations

Carboplatin Plus Paclitaxel in Unknown Primary Carcinoma: A Phase II Hellenic Cooperative Oncology Group Study

2000 • 203 citations

Metastatic Carcinomas from Occult Primary Tumors

1977 • 200 citations

Metastatic cancer of unknown primary site

1970 • 197 citations

Extraovarian peritoneal serous papillary carcinoma. A clinicopathologic study of 31 cases

1989 • 196 citations

FDG PET detection of unknown primary tumors.

2000 • 192 citations

Cancer incidence in five continents, vol. VI

1993 • 192 citations

Adenocarcinomas metastatic to the liver

1999 • 191 citations

Cervical lymph node metastases from occult squamous cell carcinoma: cut down a tree to get an apple?

2001 • 186 citations

Unknown primary adenocarcinoma: incidence of overinvestigation and natural history.

1979 • 184 citations

Advanced Poorly Differentiated Carcinoma of Unknown Primary Site: Recognition of a Treatable Syndrome

1986 • 182 citations

Early Metastatic Cancer of Unknown Primary Origin at Presentation

1988 • 176 citations

Occult Breast Cancer Presenting With Axillary Metastases

1990 • 175 citations

Management of brain metastases

2016 • 171 citations

Papillary serous carcinoma of the peritoneum

1990 • 167 citations

Poorly Differentiated Neuroendocrine Carcinoma of Unknown Primary Site

1988 • 166 citations

Treatment of the patient with adenocarcinoma of unknown origin

1972 • 164 citations

Treatment of patients with isolated axillary nodal metastases from an occult primary carcinoma consistent with breast origin

1990 • 161 citations

2[¹⁸F]‐Fluoro‐2‐Deoxy‐D‐Glucose Positron Emission Tomography is a Sensitive Tool for the Detection of Occult Primary Cancer (Carcinoma of Unknown Primary Syndrome) with Head and Neck Lymph Node Manifestation

2000 • 152 citations

Unknown Primary Head and Neck Squamous Cell Carcinoma: Molecular Identification of the Site of Origin

1999 • 149 citations

Metastatic Adenocarcinomas of Unknown Primary Site

1980 • 145 citations

Incidence of cancer in the Netherlands.

2001 • 144 citations

18F-FDG whole body positron emission tomography (PET) in patients with unknown primary tumours (UPT)

1999 • 140 citations

Papillary serous carcinoma of the peritoneum. A review of 33 cases treated with platin-based chemotherapy

1990 • 140 citations

Cancer of unknown primary site

1995 • 135 citations

Sites of primary malignancies in patients presenting with cerebral metastases.A review of 120 cases

1985 • 133 citations

Metastatic melanoma of unknown primary

1982 • 132 citations

Identifying the primary site in metastatic cancer of unknown origin. Inadequacy of roentgenographic procedures

1979 • 126 citations

Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site.

1995 • 125 citations

Feasibility of Breast Preservation in the Treatment of Occult Primary Carcinoma Presenting With Axillary Metastases

2001 • 125 citations

The Unrecognized Extragonadal Germ Cell Cancer Syndrome

1981 • 116 citations

Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma

1997 • 116 citations

Carcinoma of unknown primary site: Phase II trials with docetaxel plus cisplatin or carboplatin

2000 • 114 citations

Gemcitabine, Carboplatin, and Paclitaxel for Patients With Carcinoma of Unknown Primary Site: A Minnie Pearl Cancer Research Network Study

2002 • 112 citations

Localised disease in cancer of unknown primary (CUP): The value of positron emission tomography (PET) for individual therapeutic management

2001 • 111 citations

Cancer of Unknown Primary Origin

1997 • 110 citations

Computed tomography in the evaluation of metastatic adenocarcinoma from an unknown primary site. A retrospective study.

1982 • 93 citations

Metastatic inguinal nodes from an unknown primary neoplasm. A review of 56 cases

1987 • 86 citations

UNDIFFERENTIATED CARCINOMA IN YOUNG MEN: THE ATYPICAL TERATOMA SYNDROME

1979 • 86 citations

Brain metastases as the only manifestation of an undetected primary tumor

1998 • 86 citations

Computed tomography in search of cancer of unknown origin.

1982 • 85 citations

Unknown primary tumors metastatic to liver.

1998 • 84 citations

Carcinoma of unknown primary site

2000 • 84 citations

Identifying the Primary Site in Metastatic Cancer of Unknown Origin

1979 • 82 citations

Occult breast carcinoma presenting as axillary metastases

2000 • 81 citations

Overexpression of Her-2 in Patients With Poorly Differentiated Carcinoma or Poorly Differentiated Adenocarcinoma of Unknown Primary Site

2000 • 76 citations

Peritoneal papillary serous carcinoma with long-term survival

1986 • 71 citations

Prognostic factors in metastatic carcinoma of unknown primary.

1986 • 69 citations

Carcinoma of unknown primary: Identification of a treatable subset?

1990 • 68 citations

Management of patients with metastatic adenocarcinoma of unknown origin: a Southwest Oncology Group study.

1983 • 67 citations

Occult breast cancer presenting with axillary metastasis.

1993 • 66 citations

Metastatic cancer without a detectable primary site

1967 • 63 citations

Evaluation of six tumor markers in patients with carcinoma of unknown primary

1994 • 63 citations

Continuous infusion 5-fluorouracil, etoposide and cis-diamminedichloro platinum in patients with metastatic carcinoma of unknown primary origin

1991 • 63 citations

Axillary metastasis from occult breast carcinoma: diagnosis and management.

1995 • 60 citations

Metastatic adenocarcinoma of unknown primary site. A randomized study of two combination chemotherapy regimens

1987 • 58 citations

Computed Tomography in Search of Cancer of Unknown Origin

1982 • 58 citations

Overexpression of C-myc, Ras and C-erbB-2 oncoproteins in carcinoma of unknown primary origin.

1995 • 57 citations

A randomized Phase II trial in patients with carcinoma of an unknown primary site

2001 • 55 citations

Bcl2 and p53 protein expression in metastatic carcinoma of unknown primary origin: biological and clinical implications. A Hellenic Co-operative Oncology Group study.

1998 • 55 citations

Taxane-based chemotherapy for patients with carcinoma of unknown primary site.

2001 • 55 citations

Diagnostic persistence in working up metastatic cancer with an unknown primary site.

1980 • 54 citations

Atypical Metastasis From Prostate Cancer

1985 • 54 citations

Gemcitabine in the Second-Line Therapy of Patients with Carcinoma of Unknown Primary Site: A Phase II Trial of the Minnie Pearl Cancer Research Network

2001 • 50 citations

Pathological evaluation of neoplasms with unknown primary tumor site.

1993 • 49 citations

Carcinoma of an unknown primary site: A chemotherapy strategy based on histological differentiation – results of a prospective study

2001 • 48 citations

p53 gene mutation spectrum in human unknown primary tumors.

1993 • 47 citations

Mitomycin C, Epirubicin and Cisplatin versus Mitomycin C Alone as Therapy for Carcinoma of Unknown Primary Origin

1998 • 46 citations

Gemcitabine, Carboplatin, and Paclitaxel for Patients With Carcinoma of Unknown Primary Site: A Minnie Pearl Cancer Research Network Study

2002 • 45 citations

Genetic analysis in the diagnosis of neoplasms of unknown primary tumor site.

1993 • 42 citations

Carcinoma of Unknown Primary

2014 • 38 citations

Poorly differentiated carcinoma of unknown primary site: correlation of light microscopic findings with response to cisplatin-based combination chemotherapy.

1987 • 37 citations

Adenocarcinoma of unknown primary site. The brooke army medical center experience

1985 • 35 citations

High serum thyroglobulin levels: Diagnostic indicators in patients with metastases from unknown primary sites

1987 • 34 citations

Tumor markers in metastatic disease from cancer of unknown primary origin.

2002 • 34 citations

Metastases from Unknown Primary Tumor PET-FDG as Initial Diagnostic Procedure?

2000 • 34 citations

Fluorouracil, doxorubicin, cisplatin and altretamine in the treatment of metastatic carcinoma of unknown primary

1989 • 33 citations

A multicentre phase II study of carboplatin and prolonged oral etoposide in the treatment of cancer of unknown primary site (CUPS)

1998 • 33 citations

Multicentric Phase II Study of Cisplatin and Etoposide in Patients With Metastatic Carcinoma of Unknown Primary

2000 • 33 citations

Disseminated prostatic carcinoma simulating primary lung cancer. Indications for immunodiagnostic studies

1988 • 32 citations

Cervical lymph node metastases from occult squamous cell carcinoma

2002 • 32 citations

Chemotherapy in carcinomas of unknown primary site: A high-dose intensity policy

1999 • 31 citations

Combination Regimen with Carboplatin, Epirubicin and Etoposide in Metastatic Carcinomas of Unknown Primary Site: A Hellenic Co-Operative Oncology Group Phase II Study

1998 • 29 citations

Original article: Subsets of tumors responsive to cisplatin or carboplatin combinations in patients with carcinoma of unknown primary site

1992 • 29 citations

Secondary carcinoma in cervical lymph nodes with an occult primary tumour. A review of 61 patients including their response to radiotherapy

1970 • 28 citations

Adenocarcinoma of unknown primary site: A clinico‐pathological study

1979 • 24 citations

A phase II study of mitomycin C, cisplatin and continuous infusion 5-fluorouracil (MCF) in the treatment of patients with carcinoma of unknown primary site

2002 • 24 citations

CERVICAL LYMPH NODE METASTASES FROM CARCINOMA OF UNDETERMINED ORIGIN

1971 • 22 citations

Poorly differentiated carcinoma or adenocarcinoma of unknown primary site: long-term results with cisplatin-based chemotherapy.

1994 • 21 citations

Combination of Cisplatin-Doxorubicin-Cyclophosphamide in Adenocarcinoma of Unknown Primary Site

2001 • 20 citations

5-fluorouracil and leucovorin as second-line chemotherapy in carcinomas of unknown primary site.

2001 • 19 citations

High dose intensity of cisplatin and etoposide in adenocarcinoma of unknown primary.

1991 • 19 citations

HPV 18 and cervical adenocarcinomas.

1991 • 17 citations

Adenocarcinoma of Unknown Primary Site

2002 • 17 citations

Chemotherapy in the Management of Metastatic Cancer of Unknown Primary Site

1972 • 17 citations

Detection of primary breast cancer presenting as metastatic carcinoma of unknown primary origin by 111In-pentetreotide scan

1998 • 16 citations

Management of adenocarcinoma of unknown primary with a 5-fluorouracil-cisplatin chemotherapy regimen (CFTam)

1999 • 14 citations

Phase II trial of cisplatin for adenocarcinoma of unknown primary site

1991 • 11 citations

The evolving role of paclitaxel for patients with carcinoma of unknown primary site.

1999 • 11 citations

Poorly Differentiated Carcinoma of Unknown Primary Site

2003 • 7 citations

Chemotherapy in carcinomas of unknown primary site.

2007 • 1 citations

Deleted Work

1955 • 0 citations