(AGCTG) (AGCTG) (AGCTG) (GGGTG) as the Primordial Sequence of Intergenic Spacers: The Role in Immunoglobulin Class Switch

Mathematical model for studying genetic variation in terms of restriction endonucleases.

1979 • 10,442 citations

Selfish DNA: the ultimate parasite

1980 • 2,095 citations

Selfish genes, the phenotype paradigm and genome evolution

1980 • 1,779 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

So much "junk" DNA in our genome.

1972 • 501 citations

Organization of immunoglobulin heavy chain genes and allelic deletion model.

1978 • 297 citations

DNA Sequences Mediating Class Switching in α-Immunoglobulins

1980 • 243 citations

Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene

1979 • 230 citations

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

1980 • 213 citations

Exon shuffling generates an immunoglobulin heavy chain gene.

1980 • 146 citations

The organization of repetitive sequences in a cluster of rabbit β-like globin genes

1980 • 140 citations

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing

1980 • 121 citations

The Evolution of the Immune Response

1970 • 71 citations

Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.

1979 • 54 citations

The evolution of the immune response. XI. The immunoglobulins of the horned shark, Heterodontus francisci: purification, characterization and structural requirement for antibody activity.

1971 • 38 citations

The Evolution of the Immune Response

1971 • 24 citations

Origin of Intervening Sequences Within Mammalian Genes and the Universal Signal for Their Removal

1980 • 14 citations