CLINICAL, IMMUNOLOGICAL, AND VIROLOGICAL EFFECTS OF AMPLIGEN, A MISMATCHED DOUBLE-STRANDED RNA, IN PATIENTS WITH AIDS OR AIDS-RELATED COMPLEX

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

ADMINISTRATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE, AN INHIBITOR OF HTLV-III/LAV REPLICATION, TO PATIENTS WITH AIDS OR AIDS-RELATED COMPLEX

1986 • 806 citations

Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells

1985 • 263 citations

Defective interfering particles with covalently linked [±]RNA induce interferon

1977 • 169 citations

Viral Infection and Host Defense

1974 • 136 citations

Structural requirements of the rIn·rCn complex for Induction of human interferon

1972 • 130 citations

Antiviral activity of mismatched double-stranded RNA against human immunodeficiency virus in vitro.

1987 • 84 citations

Current issues in developing a strategy for dealing with the acquired immunodeficiency syndrome.

1986 • 48 citations

MISMATCHED DOUBLE-STRANDED RNA (AMPLIGEN) REDUCES CONCENTRATION OF ZIDOVUDINE (AZIDOTHYMIDINE) REQUIRED FOR IN-VITRO INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS

1987 • 46 citations

Loss of (2'-5')oligoadenylate synthetase activity by production of antisense RNA results in lack of protection by interferon from viral infections.

1987 • 45 citations

Clinical studies with ampligen (mismatched double-stranded RNA).

1985 • 39 citations

Antiproliferative and immunomodulatory actions of beta-interferon and double-stranded RNA, individually and in combination, on human bladder tumor xenografts in nude mice.

1985 • 28 citations

n-Decyl-NHpppA2′p5′A2′p5′A a phosphatase-resistant, active pppA2′p5′A2′p5′A analog

1985 • 26 citations

Synergistic antiproliferative effect of human interferons in combination with mismatched double‐stranded RNA on human tumor cells

1986 • 21 citations

Preclinical studies with Ampligen (mismatched double-stranded RNA).

1985 • 20 citations

Treatment of HTLV-III/LAV-infected patients with D-penicillamine.

1986 • 17 citations

A misaligned double-stranded RNA, poly(I)·poly(C12,U), induces accumulation of 2′,5′-oligoadenylates in mouse tissues

1986 • 16 citations

Comparative studies of ampligen (mismatched double-stranded RNA) and interferons.

1985 • 13 citations

2',5'-Oligoadenylate synthetase from cutaneous T-cell lymphoma: biosynthesis, identification, quantitation, molecular size of the 2',5'-oligoadenylates, and inhibition of protein synthesis

1983 • 10 citations

Utilization of Stabilized Forms of Polynucleotides

1984 • 2 citations

Deleted Work

1955 • 0 citations