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Species Variation in the Metabolism of R-(+)- and S-(-)-Nicotine by α-C- andN-Oxidationin vitro

Data up to Jan 2025

Published1973
Citations39
References15

Total Citations Per Year

Abstract

References (15)

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

Biochemical and pharmacological changes in the rat following chronic administration of morphine nalorphine and normorphine.

1959 • 734 citations

Enzymatic pathway for the formation of cotinine, a major metabolite of nicotine in rabbit liver.

1960 • 131 citations

The analysis of nicotine-1‘-N-oxide in urine, in the presence of nicotine and cotinine, and its application to the study of in vivo nicotine metabolism in man

1971 • 83 citations

A possible relation between pKa1 and lipid solubility and the amounts excreted in urine of some tobacco alkaloids given to man

1972 • 71 citations

Enzymic oxidation of (—)-nicotine by guinea-pig tissues in vitro

1971 • 67 citations

The metabolism of nicotine into two optically-active stereoisomers of nicotine-1′-oxide by animal tissues in vitro and by cigarette smokers

1970 • 59 citations

Tertiary Amine Oxide Rearrangements. III. The Mechanism of the Demethylation of Nicotine

1964 • 41 citations

Selective inhibition of alternative oxidative pathways of nicotine metabolism in vitro

1971 • 39 citations

Factors Affecting thein vitroMetabolism of R-(+)-and S-(-)-Nicotine by Guinea-pig Liver Preparations

1973 • 31 citations

Notes- Pyridine-1-oxides. IV. Nicotine-1-oxide, Nicotine-1'-oxide, and Nicotine-1,1'-dioxide

1959 • 31 citations

Metabolism in Vitro of 14C‐Nicotine in Livers of Foetal, Newborn and Young Mice

1969 • 26 citations

Sex and Strain Differences in Basal and Induced Aniline Hydroxylase and Ethylmorphine N-Demethylase Activities from Domestic and Wild Rats

1969 • 24 citations

Characterization of the Diastereoisomers of Nicotine-1′-N-Oxide, a Metabolite of Nicotine, and Other Possible Oxidation Products by Nuclear Magnetic Resonance Spectroscopy

1973 • 17 citations

Demonstration of n-epimers in the salt of a piperidine derivative in solution

1965 • 14 citations

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Species Variation in the Metabolism of R-(+)- and S-(-)-Nicotine by α-C- andN-Oxidationin… (1973) – Xenobiotica | Metascience Observatory Explorer