Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck.

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

Interaction of the IL-2 Receptor with thesrc-Family Kinase p56^lck: Identification of Novel Intermolecular Association

1991 • 576 citations

Evidence for function of Ia molecules on gut epithelial cells in man.

1987 • 521 citations

Isolation and functional characterization of human intestinal mucosal lymphoid cells.

1977 • 403 citations

Immunologic suppression after oral administration of antigen. I. Specific suppressor cells formed in rat Peyer's patches after oral administration of sheep erythrocytes and their systemic migration.

1978 • 263 citations

Antigen presentation by epithelial cells of the rat small intestine. II. Selective induction of suppressor T cells.

1986 • 252 citations

Antigenic variants of rabies virus

1980 • 212 citations

Expression and function of CD4 in a murine T-cell hybridoma

1987 • 208 citations

Murine enterocytes can present soluble antigen to specific class II‐restricted CD4⁺ T cells

1989 • 203 citations

T lymphocyte subsets in human intestinal mucosa: the distribution and relationship to MHC-derived antigens.

1981 • 194 citations

Production of immunity and unresponsiveness in the mouse by feeding contact sensitizing agents and the role of suppressor cells in the Peyer's patches, mesenteric lymph nodes and other lymphoid tissues

1977 • 173 citations

Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor

1988 • 166 citations

Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation

1988 • 163 citations

Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

1989 • 140 citations

Expression of the adhesion molecule ICAM-1 and major histocompatibility complex class I antigens on human tumor cells is required for their interaction with autologous lymphocytes in vitro

1990 • 139 citations

Proliferative responses of human intraepithelial lymphocytes to various T-cell stimuli

1989 • 138 citations

Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates

1988 • 124 citations

Cross‐linking of the T cell receptor complex with the subset‐specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells

1987 • 117 citations

Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies.

1989 • 103 citations

CD4⁺ CD8⁺ murine intestinal intraepithelial Iymphocytes

1990 • 90 citations

Human malignant T cells capable of inducing an immunoglobulin class switch.

1985 • 80 citations

Interferon ? production by human intestinal mucosal mononuclear cells

1988 • 71 citations

Expression and function of CD8 in a murine T cell hybridoma.

1987 • 63 citations

Association of Src-Like Protein Tyrosine Kinases with the CD2 Cell Surface Molecule in Rat T Lymphocytes and Natural Killer Cells

1992 • 62 citations

Blocking of human T lymphocyte functions by anti-Leu-2 and anti-Leu-3 antibodies: differential inhibition of proliferation and suppression.

1983 • 55 citations

Evidence for a regulatory role of the T8 (CD8) antigen in antigen‐specific and anti‐T3‐(CD3)‐induced lytic activity of allospecific cytotoxic T lymphocyte clones

1986 • 37 citations

Regulation of CD3-induced phospholipase C-gamma 1 (PLC gamma 1) tyrosine phosphorylation by CD4 and CD45 receptors.

1992 • 33 citations

Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells.

1980 • 24 citations

Antigen handling in the intestine mediated by normal enterocytes

1990 • 20 citations

Characterization of lymphokines mediating B cell growth and differentiation from monoclonal anti-CD3 antibody-stimulated T cells.

1989 • 16 citations