Effect of Deficiency of Tumor Necrosis Factor Alpha or Both of Its Receptors onStreptococcus pneumoniaeCentral Nervous System Infection and Peritonitis

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1996 • 947 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation

1998 • 715 citations

Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis.

1990 • 447 citations

Ischemic and Excitotoxic Brain Injury is Enhanced in Mice Lacking the p55 Tumor Necrosis Factor Receptor

1998 • 254 citations

Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice

1998 • 239 citations

C-reactive protein is protective against Streptococcus pneumoniae infection in mice.

1981 • 239 citations

Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice.

1995 • 206 citations

Immunopathologic Effects of Tumor Necrosis Factor Alpha in Murine Mycobacterial Infection Are Dose Dependent

2000 • 200 citations

Cytokine enhancement of complement‐dependent phagocytosis by macrophages: synergy of tumor necrosis factor‐α and granulocyte‐macrophage colony‐stimulating factor for phagocytosis of Cryptococcus neoformans

1992 • 173 citations

Relationship between Cell Surface Carbohydrates and Intrastrain Variation on Opsonophagocytosis ofStreptococcus pneumoniae

1999 • 170 citations

GRAM-POSITIVE SEPSIS

1999 • 166 citations

Blood-Brain Barrier Damage in Patients with Bacterial Meningitis: Association with Tumor Necrosis Factor- but not Interleukin-I

1992 • 157 citations

Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily

1996 • 125 citations

The Role of Antibody and Complement in the Reticuloendothelial Clearance of Pneumococci from the Bloodstream

1983 • 116 citations

Protective effect of recombinant tumor necrosis factor-alpha in murine salmonellosis.

1990 • 115 citations

Tumor Necrosis Factor‐α Contributes to Apoptosis in Hippocampal Neurons during Experimental Group B Streptococcal Meningitis

1997 • 112 citations

Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae

1996 • 110 citations

Rifampin Reduces Early Mortality in ExperimentalStreptococcus pneumoniaeMeningitis

1999 • 104 citations

A mouse model of Streptococcus pneumoniae meningitis mimicking several features of human disease

2001 • 103 citations

Microbiologic Findings and Correlations with Serum Tumor Necrosis Factor–α in Patients with Severe Sepsis and Septic Shock

1999 • 101 citations

Experimental pneumococcal meningitis: role of leukocytes in pathogenesis

1983 • 95 citations

Tumor Necrosis Factor and the p55TNF Receptor Are Required for Optimal Development of the Marginal Sinus and for Migration of Follicular Dendritic Cell Precursors into Splenic Follicles

2000 • 90 citations

Tumor Necrosis Factor Alpha Receptor I Is Important for Survival fromStreptococcus pneumoniaeInfections

1999 • 90 citations

Influence of Granulocytes on Brain Edema, Intracranial Pressure, and Cerebrospinal Fluid Concentrations of Lactate and Protein in Experimental Meningitis

1988 • 85 citations

Tumor Necrosis Factor-Alpha: Central Regulatory Cytokine in the Induction of Macrophage Antimicrobial Activities

1991 • 81 citations

Correction of Defective Host Response to Mycobacterium Bovis BCG Infection in TNF-Deficient Mice by Bone Marrow Transplantation

2000 • 52 citations

A fluorescent immunoassay for the quantification of C-reactive protein

1978 • 49 citations

The mouse peritonitis model: present and future use

1993 • 43 citations

The role of the spleen in the protective effect of C-reactive protein in Streptococcus pneumoniae infection.

1983 • 41 citations

Mouse C-Reactive Protein and Endotoxin-Induced Resistance

1965 • 39 citations

Synergism of Pseudomonas aeruginosa exotoxin A with endotoxin, superantigen, or TNF results in TNFR1- and TNFR2-dependent liver toxicity in mice

2000 • 36 citations

Organotypic hippocampal cultures A model of brain tissue damage in Streptococcus pneumoniae meningitis

2001 • 36 citations

The effects of cytokines, platelet activating factor, and arachidonate metabolites on C3B receptor (CR1, CD35) expression and phagocytosis by neutrophils

1990 • 30 citations

Quinupristin/dalfopristin attenuates the inflammatory response and reduces the concentration of neuron-specific enolase in the cerebrospinal fluid of rabbits with experimental Streptococcus pneumoniae meningitis

1999 • 25 citations

Granulocyte phagocytosis and killing virulent and avirulent serotypes of Streptococcus pneumoniae.

1982 • 25 citations

Rifabutin for Experimental Pneumococcal Meningitis

1997 • 23 citations

Tumour necrosis factor triggers granulocytes to internalize complement-coated virus particles.

1991 • 21 citations

Pneumococcal Meningitis-Therapeutic Studies in Mice

1975 • 17 citations

Die Pneumokokken

1905 • 7 citations