RecA protein filaments can juxtapose DNA ends: an activity that may reflect a function in DNA repair.
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References (37)
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
1976 • 225,752 citations
HOMOLOGOUS PAIRING AND STRAND EXCHANGE IN GENETIC RECOMBINATION
1982 • 443 citations
Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules
1982 • 417 citations
E. coli recA protein-directed cleavage of phage λ repressor requires polynucleotide
1980 • 352 citations
recA protein of Escherichia coli promotes branch migration, a kinetically distinct phase of DNA strand exchange.
1981 • 312 citations
Characteristics of Some Multiply Recombination-Deficient Strains of Escherichia coli
1969 • 278 citations
EcoRI endonuclease. Physical and catalytic properties of the homogenous enzyme.
1976 • 259 citations
Binding of the recA protein of Escherichia coli to single- and double-stranded DNA.
1981 • 248 citations
[26] Exonuclease III of Escherichia coli K-12, an AP endonuclease
1980 • 243 citations
Repair of DNA double-strand breaks in Escherichia coli, which requires recA function and the presence of a duplicate genome
1977 • 240 citations
ELECTRON MICROSCOPE VISUALIZATION OF CHROMATIN AND OTHER DNA-PROTEIN COMPLEXES
1978 • 230 citations
The helicity of DNA in complexes with RecA protein
1982 • 217 citations
The direction of RecA protein assembly onto single strand DNA is the same as the direction of strand assimilation during strand exchange.
1985 • 198 citations
Mechanisms of DNA replication and recombination
1984 • 187 citations
Elongation of duplex DNA by recA protein
1981 • 180 citations
Repair of DNA double-strand breaks in Escherichia coli K12 requires a functional recN product
1984 • 162 citations
Electron microscopic visualization of RecA-DNA filaments: Evidence for a cyclic extension of duplex DNA
1982 • 146 citations
Macromolecular crowding allows blunt-end ligation by DNA ligases from rat liver or Escherichia coli.
1983 • 140 citations
Visualization of RecA protein and its association with DNA: A priming effect of single-strand-binding protein
1982 • 135 citations
Isolation and visualization of active presynaptic filaments of recA protein and single-stranded DNA.
1984 • 135 citations
Visualization of SSB-ssDNA Complexes Active in the Assembly of Stable RecA-DNA Filaments
1984 • 134 citations
RecA protein rapidly crystallizes in the presence of spermidine: a valuable step in its purification and physical characterization
1985 • 108 citations
Amplification of single-strand DNA binding protein in Escherichis coli
1980 • 97 citations
The uvsX protein of bacteriophage T4 arranges single-stranded and double-stranded DNA into similar helical nucleoprotein filaments.
1985 • 74 citations
RecA protein-dependent proteolysis of bacteriophage lambda repressor Characterization of the reaction and stimulation by DNA-binding proteins.
1981 • 73 citations
Light scattering studies of the recA protein of Escherichia coli: relationship between free recA filaments and the recA.cntdot.ssDNA complex
1985 • 65 citations
Hexamine cobalt chloride promotes intermolecular ligation of blunt end DNA fragments by T4 DNA ligase
1985 • 58 citations
Degradation of Escherichia coli DNA: Evidence for limitation in vivo by protein X, the recA gene product
1979 • 56 citations
Escherichia coli recA protein protects single-stranded DNA or gapped duplex DNA from degradation by RecBC DNase.
1981 • 49 citations
Isolation of altered recA polypeptides and interaction with ATP and DNA.
1985 • 47 citations
Duplex-duplex interactions catalyzed by recA protein allow strand exchanges to pass double-strand breaks in DNA
1984 • 47 citations
Repair of DNA double-strand breaks in Escherichia coli cells requires synthesis of proteins that can be induced by UV light.
1981 • 42 citations
The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate).
1983 • 31 citations
DNA binding protein from ovaries of the frog, Xenopus laevis which promotes concatenation of linear DNA
1984 • 24 citations
10 nm RecA protein filaments formed in the presence of Mg2+ and ATPγS may contain RNA
1985 • 19 citations
Molecular Mechanisms of General Genetic Recombination: The DNA-binding Sites of RecA Protein
1984 • 18 citations
Effect of recA protein on the DNAse activities of the recBC enzyme.
1981 • 11 citations