Molecular Characterization of Recombinant Human Acidic Fibroblast Growth Factor Produced inE. coli: Comparative Studies with Human Basic Fibroblast Growth Factor

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Heparin protects basic and acidic FGF from inactivation

1986 • 856 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Interaction of heparin with human basic fibroblast growth factor: Protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan

1989 • 304 citations

Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition.

1985 • 301 citations

Purification of heparin-binding growth factors

1986 • 279 citations

Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cells.

1988 • 276 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

Stabilizing basic fibroblast growth factor using protein engineering

1988 • 153 citations

Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA.

1988 • 150 citations

Human brain-derived acidic and basic fibroblast growth factors: Amino terminal sequences and specific mitogenic activities

1986 • 112 citations

Production, biological activity, and structure of recombinant basic fibroblast growth factor and an analog with cysteine replaced by serine.

1988 • 100 citations

Effect of heparin on the stimulation of non-vascular cells by human acidic and basic FGF

1986 • 83 citations

Expression of cDNA encoding human basic fibroblast growth factor in E.coli

1987 • 81 citations

Carboxyl‐terminal structure of basic fibroblast growth factor significantly contributes to its affinity for heparin

1990 • 79 citations

Stabilization by heparin of acidic fibroblast growth factor mitogenicity for human endothelial cells in vitro

1989 • 79 citations

Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor

1988 • 77 citations

Production and characterization of human basic fibroblast growth factor from Escherichia coli.

1988 • 76 citations

Expression in Escherichia coli of a Chemically Synthesized Gene for Biologically Active Bovine Acidic Fibroblast Growth Factor

1987 • 70 citations

Biological equivalence of natural bovine and recombinant human alpha-endothelial cell growth factors.

1987 • 63 citations

An evaluation of methods to quantitate the chick chorioallantoic membrane assay in angiogenesis.

1985 • 60 citations

Fibroblast Growth Factor Release by Bovine Endothelial Cells and Human Astrocytoma Cells in Culture is Density Dependent

1989 • 59 citations

Monoclonal Antibodies Against Human Basic Fibroblast Growth Factor

1989 • 50 citations

Purification and characterization of an endothelial cell growth factor from serum-free culture medium of human diploid fibroblast cells

1986 • 10 citations