Sing the mind electric – principles of deep brain stimulation

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

Deep Brain Stimulation for Treatment-Resistant Depression

2005 • 3,877 citations

Searching for a baseline: Functional imaging and the resting human brain

2001 • 3,327 citations

Toward discovery science of human brain function

2010 • 2,940 citations

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

The human orbitofrontal cortex: linking reward to hedonic experience

2005 • 2,077 citations

Which elements are excited in electrical stimulation of mammalian central nervous system: A review

1975 • 2,007 citations

Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus

1990 • 1,875 citations

Remembering the past and imagining the future: Common and distinct neural substrates during event construction and elaboration

2006 • 1,836 citations

Pathological synchronization in Parkinson's disease: networks, models and treatments

2007 • 1,564 citations

Interpreting the BOLD Signal

2004 • 1,518 citations

Optical Deconstruction of Parkinsonian Neural Circuitry

2009 • 1,467 citations

Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease<subtitle>A Randomized Controlled Trial</subtitle>

2009 • 1,387 citations

Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation

1995 • 1,340 citations

Normal and pathological oscillatory communication in the brain

2005 • 1,219 citations

Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease

2001 • 1,119 citations

DEEP BRAIN STIMULATION

2006 • 1,014 citations

Deep Brain Stimulation to Reward Circuitry Alleviates Anhedonia in Refractory Major Depression

2007 • 968 citations

Stimulation of the Subthalamic Nucleus Changes the Firing Pattern of Pallidal Neurons

2003 • 868 citations

Translational principles of deep brain stimulation

2007 • 815 citations

Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression

2009 • 806 citations

Cellular Effects of Deep Brain Stimulation: Model-Based Analysis of Activation and Inhibition

2004 • 794 citations

Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease

2007 • 777 citations

Pain Relief by Electrical Stimulation of the Central Gray Matter in Humans and Its Reversal by Naloxone

1977 • 740 citations

Uncovering the mechanism(s) of action of deep brain stimulation: activation, inhibition, or both

2004 • 721 citations

Transient Acute Depression Induced by High-Frequency Deep-Brain Stimulation

1999 • 656 citations

Reversal of Rigidity and Improvement in Motor Performance by Subthalamic High‐frequency Stimulation in MPTP‐treated Monkeys

1993 • 609 citations

Evidence on the emergence of the brain's default network from 2-week-old to 2-year-old healthy pediatric subjects

2009 • 564 citations

Pedunculopontine tegmental nucleus of the rat: Cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum

1987 • 537 citations

Lesion of the subthalamic nucleus for the alleviation of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐induced parkinsonism in the primate

1991 • 526 citations

High-Frequency Stimulation Produces a Transient Blockade of Voltage-Gated Currents in Subthalamic Neurons

2001 • 515 citations

Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter

1998 • 491 citations

Long-term Electrical Capsular Stimulation in Patients with Obsessive-Compulsive Disorder

2003 • 486 citations

Towards a functional neuroanatomy of pleasure and happiness

2009 • 482 citations

Microstimulation-Induced Inhibition of Neuronal Firing in Human Globus Pallidus

2000 • 456 citations

Disrupted Dopamine Transmission and the Emergence of Exaggerated Beta Oscillations in Subthalamic Nucleus and Cerebral Cortex

2008 • 453 citations

Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson's disease

2005 • 448 citations

Selection of stimulus parameters for deep brain stimulation

2004 • 432 citations

Pain reduction by electrical brain stimulation in man

1977 • 432 citations

Pain reduction by electrical brain stimulation in man

1977 • 432 citations

Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: A systematic review

2006 • 421 citations

Network perspectives on the mechanisms of deep brain stimulation

2009 • 421 citations

A Quantitative Assessment of the Sensitivity of Whole-Head MEG to Activity in the Adult Human Cortex

2002 • 414 citations

Implantation of human pedunculopontine nucleus: a safe and clinically relevant target in Parkinson's disease

2005 • 413 citations

MEG: An Introduction to Methods

2010 • 392 citations

Chronic Thalamic Stimulation for the Control of Facial Anesthesia Dolorosa

1973 • 366 citations

Introduction to the programming of deep brain stimulators

2002 • 354 citations

GABAergic neurons in the rat pontomesencephalic tegmentum: Codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus

1995 • 342 citations

Competition between Feedback Loops Underlies Normal and Pathological Dynamics in the Basal Ganglia

2006 • 340 citations

Pedunculopontine nucleus and basal ganglia: distant relatives or part of the same family?

2004 • 340 citations

Mechanisms of action of deep brain stimulation (DBS)

2007 • 337 citations

Effects of high frequency stimulation of subthalamic nucleus on extracellular glutamate and GABA in substantia nigra and globus pallidus in the normal rat

2000 • 331 citations

Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter

1998 • 315 citations

Human reticular formation: Cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons

1989 • 301 citations

Computational Analysis of Subthalamic Nucleus and Lenticular Fasciculus Activation During Therapeutic Deep Brain Stimulation

2006 • 291 citations

A Patient with a Resistant Major Depression Disorder Treated with Deep Brain Stimulation in the Inferior Thalamic Peduncle

2005 • 291 citations

A15O-H2O PET study of meditation and the resting state of normal consciousness

1999 • 286 citations

Reading vascular changes in brain imaging: is dendritic calcium the key?

2004 • 274 citations

Chronic bilateral thalamic stimulation: a new therapeutic approach in intractable Tourette syndrome

2003 • 273 citations

Effects of High-Frequency Stimulation in the Internal Globus Pallidus on the Activity of Thalamic Neurons in the Awake Monkey

2003 • 273 citations

Resonant Antidromic Cortical Circuit Activation as a Consequence of High-Frequency Subthalamic Deep-Brain Stimulation

2007 • 269 citations

Mechanisms of deep brain stimulation and future technical developments

2000 • 268 citations

Effects of stimulation of the subthalamic area on oscillatory pallidal activity in Parkinson's disease

2004 • 267 citations

Stimulation of the Posterior Hypothalamus for Treatment of Chronic Intractable Cluster Headaches: First Reported Series

2003 • 252 citations

Neurobiological mechanisms of anhedonia

2008 • 247 citations

Dual Effect of High-Frequency Stimulation on Subthalamic Neuron Activity

2003 • 243 citations

High-frequency stimulation in Parkinson's disease: more or less?

2005 • 243 citations

Locomotion-inducing sites in the vicinity of the pedunculopontine nucleus

1987 • 224 citations

Deep brain stimulation for Parkinson's disease dissociates mood and motor circuits: A functional MRI case study

2003 • 210 citations

Glutamate-like immunoreactivity in neurons of the laterodorsal tegmental and pedunculopontine nuclei in the rat

1990 • 205 citations

Cortical and subcortical blood flow effects of subthalamic nucleus stimulation in PD

2003 • 205 citations

Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus

2002 • 200 citations

Cholinergic brainstem neurons modulate cortical gamma activity during slow oscillations

2008 • 199 citations

Pedunculopontine nucleus stimulation improves akinesia in a Parkinsonian monkey

2004 • 190 citations

Anatomy, physiology, and pathophysiology of the pedunculopontine nucleus

2008 • 184 citations

Deep brain stimulation in Tourette's syndrome: Two targets?

2006 • 183 citations

Hypothalamic Deep Brain Stimulation in Positron Emission Tomography

2006 • 174 citations

Blood flow responses to deep brain stimulation of thalamus

2002 • 174 citations

Experimental and theoretical characterization of the voltage distribution generated by deep brain stimulation

2008 • 173 citations

Balance of Monosynaptic Excitatory and Disynaptic Inhibitory Responses of the Globus Pallidus Induced after Stimulation of the Subthalamic Nucleus in the Monkey

2005 • 158 citations

Deep Brain Stimulation Devices: A Brief Technical History and Review

2008 • 158 citations

Excitotoxic lesions of the pedunculopontine tegmental nucleus produce contralateral hemiparkinsonism in the monkey

1997 • 156 citations

Deep brain stimulation for chronic pain

2015 • 155 citations

Late emergence of synchronized oscillatory activity in the pallidum during progressive parkinsonism

2007 • 154 citations

Long-term follow-up of bilateral hypothalamic stimulation for intractable cluster headache

2004 • 153 citations

Anatomy and physiology of the basal ganglia: Implications for DBS in psychiatry

2007 • 151 citations

Long term results of periventricular gray self-stimulation

1977 • 145 citations

Optimized beamforming for simultaneous MEG and intracranial local field potential recordings in deep brain stimulation patients

2010 • 131 citations

Deep brain stimulation of the pedunculopontine region in the normal non-human primate

2002 • 122 citations

Identification of the target neuronal elements in electrical deep brain stimulation

2000 • 121 citations

Regional brain uptake of 2-deoxyglucose in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)—induced parkinsonism in the macaque monkey

1985 • 121 citations

The role of descending basal ganglia connections to the brain stem in Parkinsonian akinesia

1998 • 116 citations

GABAergic neuron distribution in the pedunculopontine nucleus defines functional subterritories

2009 • 108 citations

Treatment resistant depression as a failure of brain homeostatic mechanisms: Implications for deep brain stimulation

2009 • 107 citations

Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: Focus on sleep and cognitive domains

2009 • 107 citations

Cerebral blood flow changes induced by pedunculopontine nucleus stimulation in patients with advanced Parkinson's disease: A [¹⁵O] H₂O PET study

2009 • 106 citations

Deep brain stimulation for chronic pain investigated with magnetoencephalography

2007 • 104 citations

Subthalamic Stimulation-Induced Forelimb Dyskinesias Are Linked to an Increase in Glutamate Levels in the Substantia Nigra Pars Reticulata

2006 • 99 citations

Active deep brain stimulation during MRI: A feasibility study

2004 • 98 citations

Cortical activation patterns evoked by afferent axons stimuli at different frequencies: an in vitro voltage-sensitive dye imaging study

2002 • 97 citations

Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State

2009 • 91 citations

[Intermittent analgesic thalamic stimulation. Preliminary note].

1973 • 88 citations

Stereotactic neurosurgical planning, recording, and visualization for deep brain stimulation in non-human primates

2006 • 79 citations

Involvement of neuronal cell bodies of the mesencephalic locomotor region in the initiation of locomotor activity of freely behaving rats

1986 • 75 citations

Preoperative Clinical Predictors of Response to Bilateral Subthalamic Stimulation in Patients with Parkinson’s Disease

2005 • 74 citations

High frequency deep brain stimulation: What are the therapeutic mechanisms?

2006 • 73 citations

Changes in cerebral blood oxygenation of the frontal lobe induced by direct electrical stimulation of thalamus and globus pallidus: a near infrared spectroscopy study

1999 • 71 citations

Evolution of Deep Brain Stimulation: Human Electrometer and Smart Devices Supporting the Next Generation of Therapy

2009 • 66 citations

Deep Brain Stimulation for Treatment-Resistant

2008 • 56 citations

Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication

2009 • 55 citations

NEURAL SIGNATURES IN PATIENTS WITH NEUROPATHIC PAIN

2009 • 51 citations

Stimulation of the Posterior Hypothalamus for Treatment of Chronic Intractable Cluster Headaches: First Reported Series

2003 • 51 citations

Cortical activation patterns evoked by afferent axons stimuli at different frequencies: an in vitro voltage-sensitive dye imaging study

2002 • 50 citations

Differential effects on locomotor activity of injections of procaine into mediodorsal thalamus and pedunculopontine nucleus

1988 • 50 citations

PET Functional Imaging of Deep Brain Stimulation in Movement Disorders and Psychiatry

2009 • 46 citations

Effect of deep brain stimulation of GPI on neuronal activity of the thalamic nucleus ventralis oralis in a dystonic patient

2003 • 45 citations

Psychiatric symptoms following surgery for Parkinson's disease with an emphasis on subthalamic stimulation.

2005 • 44 citations

Deep Brain Stimulation of Pedunculopontine Tegmental Nucleus (PPTg) Promotes Cognitive and Metabolic Changes: A Target-Specific Effect or Response to a Low-Frequency Pattern of Stimulation?

2010 • 44 citations

Deep Brain Stimulation

2009 • 41 citations

Electric field effects in hyperexcitable neural tissue: A review

2003 • 39 citations

Kainate acid lesions of the pedunculopontine region in the normal behaving primate

2001 • 35 citations

Results of the stimulation of the spinothalamic fasciculus and their bearing on the physiopathology of pain

1960 • 32 citations

Deep Brain Stimulation for Chronic Pain

2015 • 32 citations

Deep brain stimulation for cluster headache

2009 • 32 citations

Using magnetoencephalography to investigate brain activity during high frequency deep brain stimulation in a cluster headache patient

2007 • 25 citations

Thalamic Stimulation Effects on Reactive Depression

1987 • 19 citations

Neurosurgical treatment of mood disorders: traditional psychosurgery and the advent of deep brain stimulation

2008 • 17 citations

Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State

2017 • 10 citations

Deep-brain stimulation

2007 • 3 citations