Genomic Imprinting: Significance in Development and Diseases and the Molecular Mechanisms

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

Role for DNA methylation in genomic imprinting

1994 • 1,695 citations

Completion of mouse embryogenesis requires both the maternal and paternal genomes

1984 • 1,529 citations

Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis

1984 • 1,402 citations

Parental imprinting of the mouse H19 gene

1991 • 1,192 citations

Genomic imprinting in mammalian development: a parental tug-of-war

1991 • 1,178 citations

Relaxation of imprinted genes in human cancer

1993 • 792 citations

Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse

1975 • 783 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1993 • 710 citations

Differential activity of maternally and paternally derived chromosome regions in mice

1985 • 708 citations

Role of paternal and maternal genomes in mouse development

1984 • 704 citations

Inherited microdeletions in the Angelman and Prader–Willi syndromes define an imprinting centre on human chromosome 15

1995 • 606 citations

Uniparental disomy as a mechanism for human genetic disease.

1988 • 477 citations

Gametic Imprinting in Mammals

1995 • 444 citations

Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

1994 • 430 citations

Parental-origin-specific epigenetic modification of the mouse H19 gene

1993 • 419 citations

Uniparental disomy in humans: development of an imprinting map and its implications for prenatal diagnosis

1995 • 410 citations

An enhancer deletion affects both H19 and Igf2 expression.

1995 • 398 citations

Allele-specific replication timing of imprinted gene regions

1993 • 385 citations

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

1992 • 279 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader–Willi syndrome critical region

1992 • 265 citations

Homologous Association of Oppositely Imprinted Chromosomal Domains

1996 • 238 citations

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1993 • 228 citations

Imprinting mutations suggested by abnormal DNA methylation patterns in familial Angelman and Prader-Willi syndromes.

1994 • 219 citations

Parental imprinting of autosomal mammalian genes

1994 • 208 citations

Allele specificity of DNA replication timing in the Angelman/Prader–Willi syndrome imprinted chromosomal region

1994 • 195 citations

Autosomal and X-chromosome imprinting

1990 • 176 citations

Mosaic and polymorphic imprinting of the WT1 gene in humans

1994 • 172 citations

HAIRPIN-TAIL: A CASE OF POST-REDUCTIONAL GENE ACTION IN THE MOUSE EGG?

1974 • 163 citations

Imprinting analysis of three genes in the Prader — Willi/Angelman region: SNRPN, E6-associated protein, and PAR-2 (D15S225E)

1994 • 123 citations

Promoter-specific IGF2 imprinting status and its plasticity during human liver development

1995 • 117 citations

A complete YAC contig of the Prader-Willi/Angelman chromosome region (15q11–q13) and refined localization of the SNRPN gene

1993 • 94 citations

Genetic imprinting map.

1990 • 84 citations

Parental origin of chromosomes involved in the translocation t(9;22)

1992 • 83 citations

Tissue-specific and allele-specific replication timing control in the imprinted human Prader-Willi syndrome region.

1995 • 74 citations

Genomic imprinting: control of gene expression by epigenetic inheritance

1994 • 45 citations

DNA methylation and genomic imprinting in mammals

1993 • 43 citations

A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues

1995 • 40 citations

Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7

1992 • 39 citations

Parental genomic imprinting

1995 • 16 citations