Immunochemical characterization of the distinct monocyte cyclic AMP-phosphodiesterase from patients with atopic dermatitis

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

Diagnostic Features of Atopic Dermatitis

1980 • 4,910 citations

Adenosine 3‘,5‘-Phosphate in Biological Materials

1962 • 2,102 citations

Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues.

1982 • 317 citations

Hydrolysis of Cyclic Guanosine and Adenosine 3',5'-Monophosphates by Rat and Bovine Tissues

1970 • 303 citations

Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme.

1979 • 244 citations

Multiple isozymes of cyclic nucleotide phosphodiesterase.

1988 • 239 citations

Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.

1983 • 238 citations

Elevated leukocyte cyclic AMP—phosphodiesterase in atopic disease: a possible mechanism for cyclic AMP—agonist hyporesponsiveness

1982 • 226 citations

Separation of human blood monocytes and lymphocytes on a continuous percoll gradient

1980 • 184 citations

Multiple isozymes of cyclic nucleotide phosphodiesterase.

1988 • 162 citations

Increased leukocyte histamine release with elevated cyclic AMP-phosphodiesterase activity in atopic dermatitis

1983 • 143 citations

Mechanism of activation of cyclic nucleotide phosphodiesterase: requirement of the binding of four Ca2+ to calmodulin for activation.

1981 • 123 citations

Cyclic nucleotide phosphodiesterases : structure, regulation and drug action

1990 • 112 citations

Phosphodiesterase Inhibition by Ro 20-1724 Reduces Hyper-IgE Synthesis by Atopic Dermatitis Cells In Vitro

1985 • 104 citations

Heterologous desensitization of leukocytes: a possible mechanism of beta adrenergic blockade in atopic dermatitis

1981 • 81 citations

Multiple Bovine Thrombin Components

1970 • 78 citations

Leukocyte and Lymphocyte Cyclic AMP Responses In Atopic Eczema

1977 • 73 citations

Differential inhibitor effects on cyclic adenosine monophosphate-phosphodiesterase isoforms in atopic and normal leukocytes.

1993 • 71 citations

Differential recognition of calmodulin-enzyme complexes by a conformation-specific anti-calmodulin monoclonal antibody.

1986 • 67 citations

Elevated umbilical cord blood leukocyte cyclic adenosine monophosphate-phosphodiesterase activity in children with atopic parents

1984 • 64 citations

Monocyte Localization of Elevated cAMP Phosphodiesterase Activity in Atopic Dermatitis

1986 • 48 citations

Impaired H2 Histamine Granulocyte Response in Active Atopic Eczema

1979 • 45 citations

Increased leukocyte sensitivity to phosphodiesterase inhibitors in atopic dermatitis: Tachyphylaxis after theophylline therapy

1984 • 33 citations

Response of mononuclear leukocyte cyclic adenosine monophosphate-phosphodiesterase activity to treatment with topical fluorinated steroid ointment in atopic dermatitis

1989 • 16 citations

Buchbesprechung

1991 • 14 citations

Characterization of cAMP‐phosphodiesterase as a possible laboratory marker of atopic dermatitis

1988 • 13 citations