Abnormal regulation of DNA replication and increased lethality in ataxia telangiectasia cells exposed to carcinogenic agents.

On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other

1947 • 12,091 citations

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1975 • 984 citations

Radiosensitivity in ataxia-telangiectasia: a new explanation.

1980 • 784 citations

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1979 • 577 citations

ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA.

1980 • 378 citations

Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts

1976 • 365 citations

Survey of radiosensitivity in a variety of human cell strains.

1980 • 271 citations

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells

1980 • 260 citations

Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations

1978 • 209 citations

Repair of ultraviolet light damage in a variety of human fibroblast cell strains.

1977 • 209 citations

The production and repair of double strand breaks in cells from normal humans and from patients with ataxia telangiectasia

1977 • 203 citations

X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.

1980 • 201 citations

Is chromatid-type damage in ataxia telangiectasia after irradiation at G0 a consequence of defective repair?

1976 • 197 citations

Genes which increase chromosomal instability in somatic cells and predispose to cancer.

1972 • 189 citations

Ataxia telangiectasia: A cellular and molecular link between cancer, neuropathology, and immune deficiency

1982 • 183 citations

Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following γ-ray irradiation

1980 • 175 citations

Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells

1976 • 173 citations

A seventh complementation group in excision-deficient xeroderma pigmentosum

1979 • 163 citations

In vitro chromosomal radiosensitivity in “chromosomal breakage syndromes”

1973 • 149 citations

Unusual sensitivity of ataxia telangiectasia cells to bleomycin.

1979 • 148 citations

DNA chain growth during replication of asynchronous L1210 cells. Alkaline elution of large DNA segments from cells lysed on filters

1974 • 139 citations

The rate of DNA synthesis in normal human and ataxia telangiectasia cells after exposure to X-irradiation

1981 • 109 citations

Cytogenetic investigations in families with ataxia-telangiectasia

1975 • 99 citations

Ataxia telangiectasia. Evaluation of radiosensitivity in cultured skin fibroblasts as a diagnostic test.

1978 • 90 citations

Use of Purified Lesion-Recognizing Enzymes to Monitor DNA Repair in Vivo

1978 • 85 citations

The response of ataxia telangiectasia cells to bleomycin

1979 • 78 citations

Chemical mutagen hypersensitivity in ataxia telangiectasia

1976 • 77 citations

Decreased DNA repair synthesis and defective colony-forming ability of ataxia telangiectasia fibroblast cell strains treated with N-methyl-N'-nitro-N-nitrosoguanidine.

1980 • 69 citations

Distribution within chromatin of deoxyribonucleic acid repair synthesis occurring at different times after ultraviolet radiation

1980 • 63 citations

Normal repair of DNA single-strand breaks in patients with ataxia telangiectasia

1980 • 62 citations

DNA strand breakage repair in ataxia telangiectasia fibroblast-like cells

1975 • 61 citations

Ataxia Telangiectasia: An Inherited Human Disease Involving Radiosensitivity, Malignancy and Defective DNA Repair

1977 • 49 citations

Defective DNA repair and increased lethality in ataxia telangiectasia cells exposed to 4-nitroquinoline-1-oxide

1980 • 45 citations

Repair of DNA damage induced by benzo(a)pyrene diol-epoxides I and II in human alveolar tumor cells.

1978 • 44 citations

ATAXIA TELANGIECTASIA: A MODEL INHERITED DISEASE LINKING DEFICIENT DNA REPAIR WITH RADIOSENSITIVITY AND CANCER PRONENESS

1978 • 38 citations

A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia

1975 • 27 citations

Metabolism of 4-nitroquinoline 1-oxide and related compounds.

1981 • 17 citations

Unscheduled DNA synthesis in cultured ataxia telangiectasia fibroblast-like cells

1980 • 15 citations

Studies on the Repair Defects of Ataxia Telangiectasia Cells

1981 • 8 citations