Differential Suppression of Thromboxane Biosynthesis by Indobufen and Aspirin in Patients With Unstable Angina

Nonparametric Statistics for the Behavioral Sciences

1958 • 36,277 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Unstable angina. A classification.

1989 • 1,391 citations

Platelet Activation in Unstable Coronary Disease

1986 • 1,161 citations

Platelet-Active Drugs

2001 • 993 citations

Selective Cumulative Inhibition of Platelet Thromboxane Production by Low-dose Aspirin in Healthy Subjects

1982 • 940 citations

The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein.

1975 • 856 citations

Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide.

1992 • 823 citations

Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.

1983 • 675 citations

Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects

1980 • 642 citations

Thromboxane Biosynthesis and Platelet Function in Type II Diabetes Mellitus

1990 • 600 citations

Release of Prostaglandins and Thromboxane into the Coronary Circulation in Patients with Ischemic Heart Disease

1981 • 597 citations

Unstable Angina

1990 • 508 citations

Coronary Arterial Smooth Muscle Contraction by a Substance Released from Platelets: Evidence That It Is Thromboxane A ₂

1976 • 504 citations

Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases.

1994 • 500 citations

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.

1990 • 484 citations

Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications.

1989 • 461 citations

Clinical pharmacology of platelet cyclooxygenase inhibition.

1985 • 432 citations

Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2.

1993 • 293 citations

Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs.

1995 • 291 citations

Antithrombotic agents in coronary artery disease

1989 • 264 citations

Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites.

1981 • 244 citations

Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury.

1989 • 241 citations

Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.

1992 • 212 citations

Biochemical evidence of platelet activation in patients with persistent unstable angina

1987 • 178 citations

Radioimmunoassay of 11-dehydrothromboxane B2 in human plasma and urine

1987 • 144 citations

Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages

1992 • 129 citations

Cyclooxygenases-1 and −2 of Endothelial Cells Utilize Exogenous or Endogenous Arachidonic Acid for Transcellular Production of Thromboxane

1996 • 129 citations

Dissociation of Platelet Activation and Spontaneous Myocardial Ischemia in Unstable Angina

1990 • 119 citations

Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in man

1989 • 106 citations

The excretion of enalapril and enalaprilat in human breast milk

1990 • 70 citations

Effects of antiplatelet therapy with indobufen or aspirin-dipyridamole on graft patency one year after coronary artery bypass grafting

1994 • 59 citations

Immunoquantitation of thromboxane synthase in human tissues.

1990 • 51 citations

Antithrombotic Agents in Coronary Artery Disease

1995 • 40 citations

Effects of racemic, S- and R-indobufen on cyclooxygenase and lipoxygenase activities in human whole Mood

1990 • 33 citations

Aspirin, but not heparin, suppresses the transient increase in thromboxane biosynthesis associated with cardiac catheterization or coronary angioplasty

1993 • 31 citations

Effects of Unfractionated and Low Molecular Weight Heparins on Platelet Thromboxane Biosynthesis “In Vivo”

1994 • 26 citations

Inhibition of thromboxane biosynthesis and platelet function by indobufen in type II diabetes mellitus.

1993 • 21 citations

Indobufen (K 3920), a new inhibitor of platelet aggregation: Effect of food on bioavailability, pharmacokinetic and pharmacodynamic study during repeated oral administration to man

1979 • 20 citations

Indobufen versus aspirin plus dipyridamole after coronary artery bypass surgery

1991 • 18 citations

Inhibition of thromboxane biosynthesis and platelet function by indobufen in type II diabetes mellitus.

1993 • 15 citations

Intracoronary Platelet Release in Patients with and without Coronary Artery Disease

1983 • 14 citations

Fractional conversion of thromboxane B2 to urinary 11-dehydro-thromboxane B2 in man

1988 • 14 citations

Effect of pacing-induced myocardial ischemia on platelet activation and fibrin formation in the coronary circulation

1987 • 12 citations

Platelet function and exercise-induced myocardial ischaemia in coronary heart disease patients

1989 • 9 citations

Pacing induced angina and plattelet reactivity

1982 • 9 citations

Pacing induced angina and plattelet reactivity

1982 • 8 citations