Vanadate stimulates system A amino acid transport activity in skeletal muscle. Evidence for the involvement of intracellular pH as a mediator of vanadate action.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

1977 • 835 citations

Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate

1982 • 699 citations

CALCULATION OF INTRACELLULAR pH FROM THE DISTRIBUTION OF 5,5-DIMETHYL-2,4-OXAZOLIDINEDIONE (DMO). APPLICATION TO SKELETAL MUSCLE OF THE DOG*

1959 • 686 citations

Effect of pH on the Kinetics of Frog Muscle Phosphofructokinase

1966 • 647 citations

The regulation of amino acid transport in animal cells

1978 • 467 citations

Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.

1980 • 429 citations

Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action.

1987 • 409 citations

Insulin-Mimetic Effects of Vanadate: Possible Implications for Future Treatment of Diabetes

1990 • 369 citations

A novel mechanism for the insulin-like effect of vanadate on glycogen synthase in rat adipocytes.

1984 • 351 citations

Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase

1989 • 317 citations

The fate of cytoplasmic vanadium. Implications on (NA,K)-ATPase inhibition.

1979 • 282 citations

Mechanisms of Action of Vanadium

1984 • 277 citations

Stimulation of amino acid transport by insulin in the isolated rat diaphragm

1958 • 262 citations

Neutral amino acid transport. Characterization of the A and L systems in isolated rat hepatocytes.

1977 • 216 citations

Electron paramagnetic resonance studies and insulin-like effects of vanadium in rat adipocytes

1981 • 203 citations

Phosphotyrosyl-protein phosphatase of TCRC-2 cells.

1982 • 195 citations

Micro‐electrode measurement of the intracellular pH and buffering power of mouse soleus muscle fibres.

1977 • 184 citations

Effect of acetoacetate on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat

1977 • 165 citations

Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor

1983 • 162 citations

Insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes. Synthesis of a high affinity component of transport.

1979 • 155 citations

The insulin-like effect of sodium vanadate on adipocyte glucose transport is mediated at a post-insulin-receptor level

1986 • 151 citations

Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle

1985 • 143 citations

Intracellular pH in human skeletal muscle by 1H NMR.

1988 • 141 citations

Skeletal muscle glycogenolysis, glycolysis, and pH during electrical stimulation in men

1987 • 130 citations

Glucose Metabolism in Rat Skeletal Muscle at Rest: Effect of Starvation, Diabetes, Ketone Bodies and Free Fatty Acids

1974 • 129 citations

Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle.

1989 • 117 citations

The Insulin-Mimetic Effect of Vanadate Is Not Correlated with Insulin Receptor Tyrosine Kinase Activity Nor Phosphorylation in Mouse Diaphragmin Vivo

1989 • 113 citations

The Insulin-Like Effect of Vanadate on Lipolysis in Rat Adipocytes Is Not Accompanied by an Insulin-Like Effect on Tyrosine Phosphorylation*

1989 • 98 citations

Intrinsic differences of insulin receptor kinase activity in red and white muscle.

1986 • 85 citations

Insulin-induced cytoplasmic alkalinization and glucose transport in muscle cells

1986 • 81 citations

The Na+-dependent regulation of the internal pH in chick skeletal muscle cells. The role of the Na+/H+ exchange system and its dependence on internal pH.

1984 • 67 citations

Adaptive regulation of amino acid transport across the cell membrane in avian and mammalian tissues

1975 • 66 citations

Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: Inhibition by amiloride and its derivatives

1985 • 63 citations

Amino Acid Transport in Plasma‐Membrane Vesicles from Rat Liver

1980 • 62 citations

Cis-inhibition, trans-inhibition, and repression of hepatic amino acid transport mediated by System A. Substrate specificity and other properties.

1986 • 58 citations

Insulin-stimulated α-(methyl)aminoisobutyric acid uptake in skeletal muscle. Evidence for a short-term activation of uptake independent of Na+ electrochemical gradient and protein synthesis

1988 • 57 citations

Vanadate stimulates Na+H+ exchange activity in A431 cells

1984 • 54 citations

Elevation of intracellular pH by insulin in frog skeletal muscle

1979 • 48 citations

Effects of chronic administration of vanadate to the rat on the sensitivity of glycolysis and glycogen synthesis in skeletal muscle to insulin

1987 • 40 citations

31P nuclear magnetic resonance analysis of frog skin

1982 • 30 citations

Cytosolic pH during a rest-to-work transition in red muscle: application of enzyme equilibria

1987 • 24 citations

Hormone-induced system A amino acid transport activity in rat liver plasma membrane and Golgi vesicles. Evidence for a differential sensitivity to inactivation by N-ethylmaleimide during carrier maturation.

1990 • 23 citations

Differential sensitivity of insulin- and adaptive-regulation-induced system A activation to microtubular function in skeletal muscle

1992 • 21 citations

Insulin and exercise stimulate muscle alpha-aminoisobutyric acid transport by a Na+K+-ATPase independent pathway

1986 • 20 citations

Effects of perturbation of the Na + electrochemical gradient on influx and efflux of alanine in isolated rat hepatocytes

1986 • 19 citations

Modification of system A amino acid carrier by diethyl pyrocarbonate.

1991 • 17 citations

Insulin Resistance of Skeletal Muscle during Pregnancy is not a Consequence of Intrinsic Modifications of Insulin Receptor Binding or Kinase Activities*

1990 • 15 citations