Loss of single HLA Class I allospecificities in melanoma cells due to selective genomic abbreviations

Molecular classification of cutaneous malignant melanoma by gene expression profiling

2000 • 2,011 citations

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

Tumor antigens recognized by T cells

1997 • 552 citations

Enhanced Generation of Specific Tumor-Reactive CTL In Vitro by Selected Melan-A/MART-1 Immunodominant Peptide Analogues

1998 • 487 citations

Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinial relevance

1995 • 478 citations

Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptidesin vivo

1996 • 308 citations

Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

1995 • 296 citations

Sequencing of HLA class II genes based on the conserved diversity of the non‐coding regions: sequencing based typing of HLA‐DRB genes

1999 • 278 citations

Peptide antigen production by the proteasome: complexity provides efficiency

1996 • 228 citations

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

1993 • 176 citations

Frequency of down-regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression

1995 • 172 citations

Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes.

1995 • 166 citations

Heterogeneous expression of melanoma-associated antigens and HLA-A2 in metastatic melanoma in vivo

1998 • 166 citations

Loss of HLA haplotype and B locus down-regulation in melanoma cell lines.

1994 • 163 citations

Melan-A/MART-1_51–73represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4⁺T cells

2000 • 160 citations

Level of HLA antigens in locoregional metastases and clinical course of the disease in patients with melanoma.

1988 • 136 citations

Chromosome loss is the most frequent mechanism contributing to HLA haplotype loss in human tumors

1999 • 116 citations

MHC antigens in human melanomas.

1991 • 111 citations

Selective Histocompatibility Leukocyte Antigen (Hla)-A2 Loss Caused by Aberrant Pre-mRNA Splicing in 624mel28 Melanoma Cells

1999 • 104 citations

Lack of HLA class I antigen expression by melanoma cells SK-MEL-33 caused by a reading frameshift in beta 2-microglobulin messenger RNA.

1993 • 91 citations

Sequencing of HLA class I genes based on the conserved diversity of the noncoding regions: sequencing‐based typing of the HLA‐A gene

1997 • 89 citations

The sebaceous nevus: a nevus with deletions of the PTCH gene.

1999 • 78 citations

Induction of Potent Antitumor CTL Responses by Recombinant Vaccinia Encoding a Melan-A Peptide Analogue

2000 • 76 citations

Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.

2001 • 70 citations

Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1.

1995 • 68 citations

A comprehensive PCR‐SSP typing system for identification of HLA‐A locus alleles

1996 • 64 citations

Higher Frequency of Selective Losses of HLA-A and -B Allospecificities in Metastasis Than in Primary Melanoma Lesions

1998 • 62 citations

Chromosome loss with concomitant duplication and recombination both contribute most to loss of heterozygosity in vitro

1998 • 52 citations

Chromosomal Allele Loss in Primary Cutaneous Melanoma is Heterogeneous and Correlates with Proliferation

1998 • 50 citations

The eortc melanoma group exchange program: Evaluation of a multicenter monoclonal antibody study

1991 • 48 citations

HLA class I phenotype and genotype alterations in cervical carcinomas and derivative cell lines

1998 • 46 citations

Selective loss of human leukocyte antigen class I allele expression in advanced renal cell carcinoma.

1996 • 45 citations

Molecular analysis of the HLA-A2 antigen loss by melanoma cells SK-MEL-29.1.22 and SK-MEL-29.1.29.

1998 • 38 citations

Immune escape mechanisms in malignant melanoma.

1999 • 37 citations

Routine Karyotyping in Wilms Tumor

1997 • 35 citations

Expression of transporter associated with antigen processing 1 and 2 (TAP1/2) in malignant melanoma cell lines

1997 • 33 citations

Sequence analysis of the 2nd intron revealed common sequence motifs providing the means for a unique sequencing based typing protocol of the HLA‐A locus

1996 • 23 citations

Low prevalence of selective human leukocyte antigen (HLA)-A and HLA-B epitope losses in early-passage tumor cell lines.

1999 • 22 citations

Microsatellite instability analysis in tumors with different mechanisms for total loss of HLA expression

2000 • 20 citations

Inverse regulation of neuronal cellular adhesion molecule (NCAM) by IFN-? in melanoma cell cultures established from CNS lesions

1999 • 15 citations

C-Myc Represses Transiently Transfected HLA Class I Promoter Sequences not Locus-Specifically

1995 • 14 citations

Clinical significance of MART-1 and HLA-A2 expression and CD8+ T cell infiltration in melanocytic lesions in HLA-A2 phenotype patients

2001 • 12 citations

Unbalanced expression of HLA-A and -B antigens: A specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-?

2001 • 12 citations

Recognition of HLA‐A1 by murine monoclonal antibodies

1994 • 5 citations